Research Scientist @ Stanford & Palo Alto VA | Doing research on noninvasive neuromodulation & psychedelics for depression and TBI
San Francisco, CA
Joined March 2009
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John P. Coetzee retweeted
Enjoyed presenting in the symposium today around TMS induced Heart Brain Coupling including a HBC-based grid search procedure for prefrontal TMS by Jessica Jacobs, the role of inflammation in HBC's role in mediating TMS response by Bruno Pedraz, and new data on HBC as a predictor for TMS response across different datasets. Roberto Goya-Maldonado and Soili Lehto as moderators, thanks for organizing! #ECBS2026 – at Naples, Campania
John P. Coetzee retweeted
Do you live in the San Francisco Bay Area? Are you planning a psychedelic experience? Willing to have an MRI before and a few weeks after? Maybe you're eligible for our study here: carhartharrislab.com/studies…
🤖 Made with AI
John P. Coetzee retweeted
Thank you to everyone who joined us for the 6th Annual Precision Mental Health Symposium! 🧠
It was an energizing day of scientific exchange, meaningful discussions, and new connections across the precision mental health community.
🎥 Symposium recordings are now available! Revisit your favorite talks or catch up on sessions you may have missed.
🔗 Watch on our website: med.stanford.edu/pmhw/2026-p…
▶️ Explore the recordings on YouTube: youtube.com/playlist?list=PL…
Together, we are advancing research, innovation, and collaboration to change the trajectory of mental illness.
A big thank you to all of our speakers and panel chairs! Thank you for being part of this important work! 👏
#PrecisionMentalHealth #StanfordCPMH #MentalHealthResearch #Neuroscience
@teddyjakiki @NeirEshel @CRodriguezMDPhD @BStaglin @AliaCrum @manishsaggar @AnissaAbi @jorsmo @jaytucc @AlikWidge @razmm @UmaRChatterjee @LMWilliams_PhD
John P. Coetzee retweeted
#JNeurosci: Findings from Li et al. suggest that targeted disruption of the TLR4–lipid raft, the membrane platform that organizes many nociceptive channels and receptors into functional complexes, may offer a novel approach to treating neuropathic pain.
doi.org/10.1523/JNEUROSCI.12…
John P. Coetzee retweeted
🚨 NEW: Dynamic Substates of the Default Mode Network Are Associated with Mystical Experiences and Clinical Outcomes after Magnesium-Ibogaine Treatment
pre-print: medrxiv.org/content/10.64898…
we add nuance to some key themes in the DMN narrative on psychedelics (1/n)
John P. Coetzee retweeted
Congratulations to @pineurosci and the P50 team, including Stanford PMH co-authors @LMWilliams_PhD, @warmxue, @teddyjakiki, and @divyardotdotn, on this new PNAS paper. The study, led by Adam Pines during his postdoctoral work, examines how rapid-acting therapeutics, including MDMA, psilocybin, and LSD, affect cortical hierarchy and propagation across substances and species, with implications for precision psychiatry.
New work on the effects of psychedelics on hierarchical cortical propagations out in PNAS! pnas.org/doi/10.1073/pnas.25…
Counter to our expectations, psychedelics attenuated bottom-up propagations into the Default Mode Network across substances and species. Thread below:
John P. Coetzee retweeted
Excited to share this from my lab. Aging brains are an untapped resource for the AI community: biology has been stress-testing neural circuits since time began. What breaks, what holds & why? The answers could reshape how we build robust AI. 🧠
The #AI field is obsessed with making neural networks more efficient and robust. Biology ran this experiment over millions of years & we call it aging. A new perspective paper argues that aging brains, far from being just a story of decline, are a powerful testbed for theories of neural computation. How does a decision-making circuit stay flexible when its biological substrate is changing? Answering that question matters for longevity science, AI robustness, & understanding what makes brains so different from the networks we build. The tools are finally ready. 🧠 sciencedirect.com/science/ar…
John P. Coetzee retweeted
Excited to see this out in PNAS. A fabulous project by Adam Pines and the Williams lab: across psychedelics (LSD, Psilo, MDMA), species, and datasets, a very consistent story—reduced propagation of activity into the default mode network (DMN). Congrats Adam! 🧠🍄
Psychedelics may weaken the normal flow of information into higher-order systems that support abstract self-referential processing, allowing perception and cognition to become less constrained. An interesting systems neuroscience account of psychedelic action.
pnas.org/doi/10.1073/pnas.25…
John P. Coetzee retweeted
Half of mental health problems begin before 18.
We need interventions designed for young people.
Apply now to our Mental Health Award:
🔬 Mechanistic trials
🏃 Physical activity + sleep interventions
🗓️ Deadline 14 July
wellcome.org/research-fundin…
John P. Coetzee retweeted
🔬New NIH-supported research published in @JamaNetworkOpen suggests that transcutaneous electrical nerve stimulation (TENS) is a safe and effective approach for managing movement-evoked pain in fibromyalgia patients.
TENS is a non-invasive treatment that uses electrical currents to block pain signals.
Read more ➡️ bit.ly/4x9b9Cs
ALT The image features a person massaging their upper back. Text overlays the image, stating, "NIH-supported research finds effective approach for treating pain in individuals with fibromyalgia," with details about transcutaneous electrical nerve stimulation (TENS) as a treatment. The NIH logo is at the bottom.
John P. Coetzee retweeted
We are seeking postdoctoral fellows interested in health psychology, sleep, psychedelic therapy responses, polycrisis resilience, and data science methods for frontiers in the biology of emotional well being.
John P. Coetzee retweeted
Development of Bioisosteres of Iboga Alkaloids: A Step-Economical Synthesis to Enhance the Antinociceptive and Anxiolytic Activity with Neuroprotective Effects | ACS Pharmacology & Translational Science pubs.acs.org/doi/10.1021/acs…
John P. Coetzee retweeted
AB 2489, the California Veterans’ Right to Try Act, is proposed legislation that would direct the state’s Research Advisory Panel to pursue FDA approval for veteran-focused clinical trials studying psychedelic-assisted therapies, including psilocybin and ibogaine.
The bill aims to help remove barriers that have long limited research participation for veterans living with complex conditions like PTSD, traumatic brain injury, depression, and substance use disorders.
VETS is proud to support AB 2489 and advocate for research that better reflects the realities veterans face.
Stay informed. Follow the conversation. Support veteran-focused research. See vets.today/43aGirf for more.
John P. Coetzee retweeted
🧠 How can personalized brain imaging help advance more targeted treatments for #BipolarDisorder?
Excited to share more about our work with @BD2Discoveries. Our team at @WeillCornell (@immanuel_elbau, Lindsay Victoria, @amykooz), in collaboration with @StanfordMed (Cammie Rolle, @DrCoreyKeller), is using individualized brain imaging to better understand brain circuits involved in mood regulation and to inform more precise stimulation-based interventions.
Grateful to be part of this broader effort to move toward more personalized approaches to bipolar disorder care.
A move toward precision psychiatry: Charles Lynch, PhD and his BD² Discovery team at @WeillCornell, in collaboration with @StanfordMed, are using personalized brain imaging to tailor targeted interventions for #bipolardisorder.
John P. Coetzee retweeted
Some good news: New research from Harvard Medical School has found that youth suicides were 11 percent lower than expected -- that's 4372 fewer deaths -- during the period after the rollout of the 988 hotline.
@LiuMichaelMD @vrpatel97 @AnupamBJena
nytimes.com/2026/04/22/scien…
John P. Coetzee retweeted
Our paper is out: By analysing health records from millions of real-world patients from the literature, we can now finally answer the questions about the long-term outcomes of ECT. What we found, consistently, across well-designed studies from the UK, Canada, US, Sweden, Denmark, and Taiwan, is that ECT does not increase the risk for dementia, heart attacks or stroke, and is associated with a significant reduction in overall mortality.
cambridge.org/core/journals/…
John P. Coetzee retweeted
Suicidal crisis: first regulatory approval of IV racemic ketamine - The Lancet thelancet.com/journals/lance…
John P. Coetzee retweeted
Scientists find that key aspects of ketamine’s antidepressant effects are preserved under anesthesia. This news and more in The Microdose's This Week in Psychedelics.
Read and subscribe: bit.ly/41Gs4Oc
John P. Coetzee retweeted
Our new viewpoint in @JAMAPsych discussing a new class of biomarkers: “targeting biomarkers”—biological signals that directly guide where, when, and how treatments are delivered.
jamanetwork.com/journals/jam…
@foxmdphd @AFornito @Arshiya_San
