@JiabeiLin
Joined August 2015
  • Tweets56
  • Following363
  • Followers93
JiaBei Lin retweeted
ShorterLab@ShorterLabAug 11
Biased stochastic motor dynamics drive bidirectional, processive translocation by the AAA+ disaggregase Hsp104: biorxiv.org/content/10.64898… – at Millbourne, PA
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AAA+ proteins: one motor, multiple ways to work, it was great to write this review for @BiochemSoc Trans @PPPublishing with @JiabeiLin & @LuciusLab: portlandpress.com/biochemsoc…
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The FDA should allow Moderna and Pfizer to update their #COVID vaccine to match the mRNA to Beta, Delta, and/or #Omnicron. It would be much more effective than boosting with the original Spike and would be comparable to the way we treat seasonal influenza virus vaccines each year
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Congratulations to our Dept. Chair, Kristen W. Lynch, PhD (@KristenWLynch1), recipient of the 2021 Michael P. Nusbaum Graduate Student Mentoring Award! This award is well-earned.
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An excellent defense lecture by @Ryan_Cupo!!! @PennPGG @pennbgs
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Daxx represents a new type of protein-folding enabler, excited that this work with Xiaolu Yang, @MarmorsteinLab, @JiabeiLin et al. is out in @Nature! nature.com/articles/s41586-0…
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Comparative analysis of the coordinated motion of Hsp70s from different organelles observed by single-molecule three-color FRET pnas.org/content/118/33/e202…

Comparative analysis of the coordinated motion of Hsp70s from different organelles observed by...

Cellular function depends on the correct folding of proteins inside the cell. Heat-shock proteins 70 (Hsp70s), being among the first molecular chap...

pnas.org
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Dr. Katalin Kariko, 66, is known to her colleagues as Kati. She's now also known as one of the heroes of coronavirus vaccine development. Alongside her collaborator, Dr. Drew Weissman, she laid the groundwork for the Pfizer-BioNTech and Moderna vaccines. nyti.ms/2OxWLDc
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Multi-scale 3D Cryo-Correlative Microscopy for Vitrified Cells sciencedirect.com/science/ar… "Our proof-of-concept benchmark revealed...the ultrastructure of protein inclusions that recruit fluorescently-labeled chaperone Hsp104." @Structure_CP
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Please retweet: reminder to register for the The 26th Annual Midwest Stress Response and Molecular Chaperone (Virtual) Meeting, to be held Saturday, January 16, 2021, 9:00am-2:00pm CDT by Zoom webinar. Please see: groups.molbiosci.northwester… #proteostasis #hsp70 #hsp90
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JiaBei Lin retweeted
Ryan Cupo@Ryan_Cupo28 Oct 2020
Very cool paper from James Berger Lab: The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader biorxiv.org/content/10.1101/…
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JiaBei Lin retweeted
Bede Portz@YSPTSPS1 Aug 2020
Anyone else with young school aged kids want to discuss what their plans are for fall, particularly if your children’s school is fully online? Feel free to DM. Floated ‘pod’ idea with other parents but got complicated fast.
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Allow International Students to Finish Their Degrees petitions.whitehouse.gov/pet…
JiaBei Lin retweeted
ShorterLab@ShorterLab7 Jul 2020
R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation: nature.com/articles/s41467-0…

R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation

Nature Communications - G-quadruplex (G4) forming sequences are highly enriched in the human genome and function as important regulators of diverse range of biological processes. Here the authors...

nature.com
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Congratulations to Justin on successfully defending his MS thesis today! He is the first graduate student to do so from my lab! He has worked hard to reach this day. @Justin_Marsee
Charles C. Chusuei@doctorCcubed6 Jul 2020
Congrats to Justin Marsee for successfully defending his Chem MS thesis today! 7-6-2020
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JiaBei Lin retweeted
Ryan Cupo@Ryan_Cupo23 Jun 2020
The full tweet thread from out preprint can be found here: xitter.cf/Ryan_Cupo/status/12188…
Ryan Cupo@Ryan_Cupo19 Jan 2020
Very excited to share some of my PhD work in the @ShorterLab Skd3 (human CLPB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations biorxiv.org/content/10.1101/… @biorxiv 1/n
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JiaBei Lin retweeted
ShorterLab@ShorterLab6 May 2020
Dedicated to Professor S. Walter Englander on the occasion of his 90th birthday :)
ShorterLab@ShorterLab6 May 2020
Membrane Proteins Have Distinct Fast Internal Motion and Residual Conformational Entropy: onlinelibrary.wiley.com/doi/…
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Rapid development of an inactivated vaccine candidate for SARS-CoV-2 science.sciencemag.org/conte…
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Wonderful new animation by @janetiwasa of the ClpAP nanomachine degrading polypeptide! @SouthworthLab @luciuslab @JiabeiLin @alex_rizo @KyleELopez95: youtube.com/watch?v=VrmhhhPn…

ClpAP: Disaggregation and Proteolytic Machine (NSMB. 2020)

Animation of the ClpAP complex in the process of degrading a GFP-Re...

youtube.com
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Hey everyone check out our paper that is finally out. Great work from everyone involved. @alex_rizo @HaraQQiri @JiabeiLin @LuciusLab @ShorterLab @ShorterLabGroup @SouthworthLab @NatureSMB nature.com/articles/s41594-0…
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