@KT_Kindt

Investigator @NIDCD @NIH. Sensory cell neurotransmission & imaging lab. Using zebrafish to visualize how hearing and balance works! All opinions are my own.

 Bethesda, MD
neuroscience.nih.gov/Faculty/Profile/katie-kindt.aspx
Joined July 2018
  • Tweets55
  • Following52
  • Followers361
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Katie kindt retweeted
Saman H@Samanical13 Jul 2024
Excited to share that my latest work in @kt_kindt ‘s lab studying the role of microtubules in ribbon synapse formation is out as a reviewed preprint in @elife. We performed live microscopy in zebrafish hair cells and observed some very interesting events! elifesciences.org/reviewed-p…
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It’s moments like this that I’m glad I run a lab :) go zebrafish!
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Our latest preprint on how new synaptic vesicles reach ribbon synapses is out! biorxiv.org/content/10.1101/…
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Very excited that our new preprint visualizing ribbon synapse formation is out! biorxiv.org/content/10.1101/…

Microtubule networks in zebrafish hair cells facilitate presynapse transport and fusion during...

Sensory cells in the retina and inner ear rely on specialized ribbon synapses for neurotransmission. Disruption of these synapses is linked to visual and auditory dysfunction, but it is unclear how...

biorxiv.org
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Katie kindt retweeted
Juan Angueyra@Juanonyme1 Mar 2024
To add new members sign in (after making an account) and add them. If you or someone else has an entry in Neurotree (neurotree.org/neurotree) or other academic trees, you can fill this form (forms.gle/Yk7DwGcUpuwM2jfz9) and we will cross-list your profile to danioTree.
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Congrats to Keith Ameyaw (Weinstein lab) & Sandeep David (Kindt lab) for winning the Postbac/Undergrad Poster Prizes! #MARZ2023
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Now online @JARO_News Dexamethasone is used to treat sudden hearing loss 💊 It is thought that maintaining high levels of dex in the ear may lead to better clinical outcomes 💉👂 But too much dex may not be a good thing for sensory hair cells😳 link.springer.com/article/10…

Prolonged Dexamethasone Exposure Enhances Zebrafish Lateral-Line Regeneration But Disrupts Mitoch...

Journal of the Association for Research in Otolaryngology - The synthetic glucocorticoid dexamethasone is commonly used to treat inner ear disorders. Previous work in larval zebrafish has shown...

link.springer.com
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So glad to hang with like minded scientists at the Auditory GRC!
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I love the postbac training program at the NIH! But it is always bittersweet when these trainees move on. Farewell Alma Jukic and best of luck in Med school!
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Katie kindt retweeted
Dabdoub Lab@LabDabdoub9 Apr 2022
Apply by May 16 to Biology of the Inner Ear Course. Tuition, room and board provided. Please RT. mbl.edu/education/advanced-r…
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Congrats to Dr. Lukasz on her amazing PhD defense!! So proud!
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Our new preprint it out! Work by grad student Daria Lukasz reveals how neurotransmission is a key part of what makes sensory hair cells so fragile biorxiv.org/content/10.1101/…

Chronic neurotransmission increases the susceptibility of lateral-line hair cells to ototoxic...

Sensory hair cells receive near constant stimulation by omnipresent auditory and vestibular stimuli. To detect and encode these stimuli, hair cells require steady ATP production, which can be...

biorxiv.org
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YES! Apply to join us at BIE 2022! @KT_Kindt, @trapanilab & I will show you some of the amazing techniques we use in zebrafish to understand how hair cell organs develop, function, die, and regenerate 🐟👂😀
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Katie kindt retweeted
NIH NIDCD@NIH_NIDCD15 Dec 2021
The NIDCD Division of Intramural Research invites outstanding scientists to apply for a tenure-track position to join an extraordinary team of researchers in communication disorders! Learn more about applying: bit.ly/3D7gH32 #NIHjobs #NIDCDjobs
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Why I started my lab at the NIH- so many great collaborators-check out our preprint on photoreceptor cell fate. biorxiv.org/content/10.1101/… @NEI @NIDCD

Identification of transcription factors involved in the specification of photoreceptor subtypes

During development, retinal progenitors navigate a complex landscape of fate decisions that culminates with an array of unique cell types that are required for proper vision. Here, we aim to identify...

biorxiv.org
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Excited to share our imaging study exploring patterns of spontaneous activity in the developing lateral-line system, now in preprint! biorxiv.org/content/10.1101/…

Using light-sheet microscopy to study spontaneous activity in the developing lateral-line system

Hair cells are the sensory receptors in the auditory and vestibular systems of all vertebrates, and in the lateral-line system of aquatic vertebrates. During development, spontaneous activity in hair...

biorxiv.org
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FDA Issues Landmark Proposal to Improve Access to Hearing Aid Technology for Millions of Americans fda.gov/news-events/press-an… Good news :)
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Finally out! mouse @JAX + fish @NIDCD show that GPR156 plays a conserved role in reversing hair cell orientation nature.com/articles/s41467-0…

EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia

Nature Communications - Sensory hair cells develop an asymmetric architecture to restrict stimulus detection to a single axis. Here the authors identify GPR156 as directing a 180-degree reversal in...

nature.com
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