Post-Doc @mrccbu @Cambridge_Uni | Computational Neuroscience and stuff.
Joined October 2017
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🔥Our opinion piece with @DuncanAstle on “why we might be better off accepting and embracing the fact that the brain’s connectivity profile is in no way optimal” is now out on @TrendsCognSci. There, we discuss implications for Neuro-AI and psychopathology.
cell.com/trends/cognitive-sc…
Kayson Fakhar retweeted
Nature research paper: Functional architecture of the human insula
go.nature.com/47R8mm9
Kayson Fakhar retweeted
🚨 New preprint! 🧵
Brain regions 🧠 integrate information over different timescales ⏱️: short in sensorimotor cortex, long in association cortex. But do regions change their timescales when we engage in a task? And how does that flexibility develop? 👇
biorxiv.org/content/10.64898…
Kayson Fakhar retweeted
Do brain connections just carry information between regions, or do they transform it?
Lab's latest out in Nature Neuroscience, led by Lakshman Chakravarthula: "Network geometry shapes the transformation of task representations across the human cortex"
colelab.org/pubs/Chakravarth… 1/n
Kayson Fakhar retweeted
In 1934, we added a gender-neutral pronoun for a single third person.
‘Thon’ was short for “that one.”
It didn’t catch on.
ALT Definition of 'thon' thon | pronoun | a proposed genderless noun of the third person
Kayson Fakhar retweeted
'Resilience and vulnerability in the midbrain dopamine system during aging'
Review by Gary McMurtrie, Samuel Mabry, Jill Glausier, Emily Rocha & Zachary Freyberg
cell.com/trends/neuroscience…
Kayson Fakhar retweeted
Why We Systems Neuroscientists Should (Usually) Be Quietists: The Philosophical Logic of NeuroAI -- response to David Barack kording.substack.com/p/why-w…
It reminded me of this very annoying concept “causation by absence.” A house burns down, partially also because of all the things that didn’t happen like the fire brigade didn’t make it on time or someone didn’t check the stove.
academic.oup.com/book/39081/…
Neuroscientists Giulio Tononi, Christof Koch, et al. make a strong case for real free will (not an illusion) if Integrated Information Theory (IIT) is the correct explanation of consciousness:
"If IIT is right, we do have free will in a genuine sense: we have alternatives, reasons, and values, we make decisions, and we—not our neurons or atoms—are the cause of our willed actions and bear responsibility for them."
arxiv.org/abs/2206.02069
Kayson Fakhar retweeted
My paper on motor cortex during free flight in bats is online. The dynamics look quite different from the usual picture. Maybe because flight is a hard control problem: hand-like wings, many degrees of freedom, millisecond precision.
cell.com/cell/fulltext/S0092…
Kayson Fakhar retweeted
Limitations of pupil diameter as a proxy for modes of locus coeruleus activity: elifesciences.org/reviewed-p…
"baseline-evoked relationships of the pupil are not predictive of those in the LC, and vice versa."
Kayson Fakhar retweeted
𝗛𝗲𝘁𝗲𝗿𝗮𝗿𝗰𝗵𝘆 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻
New preprint with Andrea Gambarotto. Neuroscience often treats control as a hierarchy: the structures behind a behavior hold a stable rank. We argue this mistakes a configuration for an architecture. 🧵
arxiv.org/abs/2610.04643
Kayson Fakhar retweeted
Thanks to everyone sharing in this moment!
I’m so grateful to my trainees & collaborators…
dlab.stanford.edu/group-memb…
(pic: optogenetics conference chairs, Tuscany)
Reading for all those asking:
for technical details: dlab.stanford.edu
for everyone: deisseroth.org/projections
Kayson Fakhar retweeted
I had a feeling recently that seems to be corroborated by chats with colleagues, so I decided to share it here.
A lot of systems neuroscientists driven by algorithmic-level questions are going through what looks and feels like a research depression. 🧵
(1/n)
Kayson Fakhar retweeted
Does biological wiring make a better reservoir?
Our WIVACE 2026 paper benchmarks different C. Elegans connectomes. Randomized baselines often perform better; results depend on the task and configuration.
arxiv.org/abs/2609.30508
#ALIFE #NeuroAI
Kayson Fakhar retweeted
1/ 🚨 Just out in @NatureNeuro! 🧠
We profiled >6,000 features of brain dynamics across humans + monkeys, mice, fish and worms 🧑🐒🐒🐁🐟🪱 to find a shared neural endpoint of anaesthesia: spatiotemporal isolation of local activity 🧵
🔗 doi.org/10.1038/s41593-026-0…
Kayson Fakhar retweeted
What kinds of dynamical structures have scientists developed models for?
Introducing the 1000×1000 collection: 1000 simulated time series × 1000 samples from 133 dynamical processes, from noise and chaos to hearts, brains and climate.
Have a play? 🐛
dynamicsandneuralsystems.git…
Kayson Fakhar retweeted
𝗪𝗵𝘆 𝗶𝘀 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻 𝘀𝗼 𝗵𝗲𝘁𝗲𝗿𝗼𝗴𝗲𝗻𝗲𝗼𝘂𝘀 (𝗮𝗻𝗮𝘁𝗼𝗺𝘆, 𝗺𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿)?
Maybe it contributes to large scale dynamics.
doi.org/10.1073/pnas.2532072…
Kayson Fakhar retweeted
Thankful to be part of this fab collab led by @TrangCao2016, S Saha, & Z Tao showing that geometric eigenmodes facilitate identification of potential biomarkers for hereditary ataxias:
sciencedirect.com/science/ar…
Kayson Fakhar retweeted
Cambridge University announces a new Cambridge Mind and Brain Institute focused on understanding and improving brain health across our lifespan, from early childhood through to old age.
This autumn, it will welcome its first cohorts of postgraduate students and researchers, providing exceptional training in cutting-edge research topics and techniques.
Find out more 👉 bit.ly/3VzHOTj
ALT A large red-brick building with multiple windows and a glass conservatory is surrounded by greenery. A news headline reads, "Cambridge University announces a new Cambridge Mind and Brain institute."
Kayson Fakhar retweeted
Spatial organization of AQP4 water channel expression in the human brain | doi.org/10.1126/sciadv.aeg81…
Aquaporins are a key component of the glymphatic system. How are they distributed + how do they relate to brain function and dysfunction? @ScienceAdvances ⤵️
