@KevinHaigisLab

Integrating Cancer Biology and Systems Biology to Identify New Therapeutic Opportunities, focusing on the RAS oncoproteins.

 Dana Farber Cancer Institute
haigislab.org
Joined August 2018
  • Tweets222
  • Following256
  • Followers1.4K
19Media
Drumroll please...🥁 Our February 2025 meetings are now LIVE on our website! We're super excited to be heading to a BRAND NEW location, the Dominican Republic! 🇩🇴 We have some amazing conferences scheduled, head to our conference website for more info➡️fusion-conferences.com/confe…
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Congrats Kevin Haigis, PhD, @DanaFarber's Chief Scientific Officer - recognized as a Fellow of the American Association for the Advancement of Science (@aaas) for distinguished contributions within biological sciences. @KevinHaigisLab Press release: ms.spr.ly/6019Y6Whf
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Fay Nicolson@NicolsonFay5 Jan 2024
Hard launch! First week as a #NewPI @DanaFarber 👩‍🔬 Interested in molecular imaging, chemistry or radiobiology? Postdoc and research tech positions to follow soon! Eternally grateful to @KevinHaigisLab and the lab for their support over the last 3.5 years 🧬🧫🧪☢️⭐️🔬
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Anirban Maitra@Aiims174210 Nov 2023
In @CEBP_AACR Effects of KRAS genetic interactions on outcomes in #LungCancer, #PancreaticCancer & #ColorectalCancer aacrjournals.org/cebp/articl… Mining the massive @AACR GENIE database, this study identifies the prognostic impact of KRAS mutations on survival (across all three cancers, harboring a KRAS mutation has a deleterious impact on survival versus wild type alleles), although there are clear specific effects of individual variants. @KevinHaigisLab @KenLauLab @skopetz
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A new leader of @NIH! Congratulations Dr. Bertagnolli!
Dana-Farber
@DanaFarber8 Nov 2023
Congratulations to Monica Bertagnolli, MD, on being confirmed by the U.S. Senate to lead the @NIH. As leader of the @theNCI, she demonstrated she has the talent to advance the mission of the agency. We’re excited to witness her impact on the health of our nation.
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Cancer Research@CR_AACR24 Oct 2023
From the newest issue— Allosteric Regulation of Switch-II Domain Controls #KRAS Oncogenicity, by @simanshu, @FredNatLab, @KevinHaigisLab et al. bit.ly/3SbUOuB @DanaFarberNews
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NEW! On the RAS Dialogue Blog, Drs. Olesja Popow and Kevin Haigis share their insights into the persistent question of why #KRAS mutations drive cancers in some tissues and not in others. spr.ly/6010PUzzG

RAS Initiative | Frederick National Laboratory

The National Cancer Institute RAS Initiative endeavors to better understand the RAS oncogene and discover its vulnerabilities to treat RAS-related cancers. About one-third of all human cancers are...

frederick.cancer.gov
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A special thank you to Clint Stalnecker and Channing Der @derlabunc for writing an excellent preview for our Molecular Cell paper out this week. cell.com/molecular-cell/full…

KRAS regulation of miRNA: Stepping on the brake to go faster

In this issue of Molecular Cell, Shui et al.1 use a systems biology approach to unravel a paradoxical role of microRNA in oncogenic KrasG12D regulation of gene and protein expression.

cell.com
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Next up, our very own conference chair @KevinHaigisLab takes the stage with a talk on TISSUE-SPECIFIC ONCOGENICITY OF K-RAS #AMC23
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Julien Sage@SageJulien18 Jul 2023
⁦@KevinHaigisLab⁩ opening remarks for the first Fusion conference ⁦@Fusion_Conf⁩ on animal models of cancer #AMC23
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What a group! Some fantastic research shared so far, and even more to come, including our Poster Session, Gala Dinner and a Wine Tour at a local vineyard🐭🍷 #AMC23
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Congratulations to the newly minted Dr. Bing Shui on his paper describing the global regulation of miRNA function by oncogenic K-Ras. Another piece of the puzzle. cell.com/molecular-cell/full…

Oncogenic K-Ras suppresses global miRNA function

Shui et al. report the in vivo de-repression of global miRNA targets induced by the oncogenic K-Ras (K-RasG12D) that is paradoxically accompanied by the enhanced Ago2:mRNA binding. Integrating...

cell.com
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Cancer Discovery@CD_AACR29 Jun 2023
Check out the Cancer Discovery papers highlighted in the new @AACR Journals collection, Targeting KRAS. bit.ly/435Ncvm @norbertkraut1 @KevinHaigisLab @AnnaFaragoMD
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What's to blame for certain cancer outcomes? A pair of studies shows the Y chromosome plays a key role in colon and bladder cancers. @DanaFarber's Chief Scientific Officer Kevin Haigis (@KevinHaigisLab) talks with @USATODAY about the findings: usatoday.com/story/news/heal…

What's to blame for certain cancer outcomes? New studies confirm: sex matters

A pair of studies shows the Y chromosome, which characterizes males, plays a key role in some cancers.

usatoday.com
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Don't forget to register before Friday! #AMC23 is shaping up to be a fantastic meeting, with an incredible line up of speakers & opportunities for poster presentation across the programme. 📌Poster submission: 19 May 2023 📆Registration: 19 May 2023 🌐fusion-conferences.com/confe…
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Andrea Ventura@aventura714 Apr 2023
We are recruiting a research tech with some experience in handling a mouse colony. Location: MSKCC, Manhattan. Competitive pay and benefits. Email: [email protected] if interested. Please RT
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The Jimmy Fund
@TheJimmyFund22 Mar 2023
Register today for @DanaFarber’s CSO Forum on 3/28 to learn how scientific collaborations with researchers and physicians worldwide help advance revolutionary science and extraordinary care for patients with cancer. Sign-up today for this virtual event: dfci.zoom.us/webinar/registe…
A photo of Dana-Farber with a photo of a scientific beaker behind it overlayed in blue with an orange rectangle over the image that reads: “CSO Forum: A Conversation with our Chief Scientific Officer”.

ALT A photo of Dana-Farber with a photo of a scientific beaker behind it overlayed in blue with an orange rectangle over the image that reads: “CSO Forum: A Conversation with our Chief Scientific Officer”.

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Tali Lev@TaliLev1236 Mar 2023
🌟At #AACRras23: @KevinHaigisLab speaks about K-RAS hyperexchange mutants in colorectal cancer. See his Review article published in @CD_AACR last year: Classification of KRAS-Activating Mutations and the Implications for Therapeutic Intervention 👇 aacrjournals.org/cancerdisco…

Classification of KRAS-Activating Mutations and the Implications for Therapeutic Intervention

AbstractMembers of the family of RAS proto-oncogenes, discovered just over 40 years ago, were among the first cancer-initiating genes to be discovered. Of the three RAS family members, KRAS is the...

aacrjournals.org
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Kevin Haigis Lab retweeted
Tali Lev@TaliLev1236 Mar 2023
🌟🌟🌟@KevinHaigisLab speaks today at #AACRras23. Find his review about Classification of KRAS-Activating Mutations and the Implications for Therapeutic Intervention published last year in @CD_AACR for the 40 years anniversary 👇 aacrjournals.org/cancerdisco…
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Deadline Extended! There's just one more week to secure discounted registration & submit an abstract for talk consideration at #AMC23. With an incredible speaker line up, this is not one to miss! 📆Talk submission: 03 Mar 2023 🌐fusion-conferences.com/confe… @KevinHaigisLab @SageJulien
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