Bram Koster (@KosterLab) header
Bram Koster (@KosterLab) profile picture

Interested in electron microscopy in all its flavors, but lately especially in combining cryo electron tomography with artificial intelligence.

Leiden, The Netherlands
Joined February 2016
Photo by Bram Koster (@KosterLab)Photo by Bram Koster (@KosterLab)Photo by Bram Koster (@KosterLab)Photo by Bram Koster (@KosterLab)Photo by Bram Koster (@KosterLab)Photo by Bram Koster (@KosterLab)Photo by Bram Koster (@KosterLab)Photo by Bram Koster (@KosterLab)Photo by Bram Koster (@KosterLab)Photo by Bram Koster (@KosterLab)
Precision super-resolution cryo-correlative light and electron microscopy for rapid in situ structural analyses of optogenetically-positioned organelles biorxiv.org/cgi/content/shor…
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Today visiting the Francis Crick Institute in London! An amazing place where they perform awesome electron microscopy on such a wide variety of samples!
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napari-animation has had a much needed upgrade! 🥳 The @napari_imaging plugin now includes contributions from 10 people 😍🧑‍🤝‍🧑 Special thanks to @KA_Hutchings, a talented student from @cjrlab this summer, for many significant usability improvements! ⚒️ github.com/napari/napari-ani…
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Bram Koster retweeted
We optmized in situ cryoET to achieve 6 A reconstructions of mouse sperm doublets! The unique tertiary structures allow de novo protein identification of novel sperm proteins by computationally searching in the AlphaFold2 library of entire mouse proteome! biorxiv.org/content/10.1101/…
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📢The speaker of the next I2PC Seminar Series on #CryoET will be Jorge Jiménez de la Morena from @CNB_CSIC 📔Talk: ScipionTomo: a cryoET framework. ⏰ Sept29th 15:00 Madrid GMT+2 conectaha.csic.es/b/bla-rkh-…
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This newly published review by eBIC staff discusses recent examples on how cryoET can be used to study membrane remodelling processes. Find the paper here: doi.org/10.1016/j.sbi.2022.1…
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Seeking a postdoc to build super-resolution cryo-fluorescence microscope (#CLEM, #teamtomo) in collaboration with Huang group of #PurdueEngineering. Info and application at engineering.purdue.edu/Engr/…. Please RT!
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Correlative light electron microscopy using small gold nanoparticles as single probes. arxiv.org/abs/2209.07771
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HOPE-SIM, a cryo-structured illumination fluorescence microscopy system for accurately targeted cryo-electron tomography biorxiv.org/cgi/content/shor…
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Bram Koster retweeted
🐣 New feature 🐣 You can now download datasets in webKnossos using the Python library. Just follow the steps indicated in the UI and integrate it in your own scripts!
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Hello #teamtomo! Have you loved every FIB slice, tomogram & sub volume at #tomo2020? Great news! Andrew Leis & I will be co-chairing #tomo2024 & #tomo2026! We’ll be headed ‘down under’ to Melbourne, AUS in 2024 & ‘up North’ in Madison, WI USA in 2026! #koalas & #Badgers 🐨🦡❄️🔬
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Bram Koster retweeted
This recent paper in @Dev_Cell includes Serial Block Face Imaging on a @thermosciEMSpec Apreo Volume Scope followed by segmentation and visualization in Amira Software! Great study, and congrats to the authors.
New study by Ivan Bedzohv’s team @emselor published in @Dev_Cell identifies Rap1 as a central factor for orchestrating the morphogenetic program that reshapes the epiblast. Congratulations 🎉 to the entire team on this great work!
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How does the yeast nuclear pore complex ‘punch’ a hole in the nuclear envelope to create a functional transport channel? A recent collaborative study from the @KarstenWeisLab implicates the protein Brl1 in this membrane fusion event. More: biol.ethz.ch/en/news-and-eve…
On my way to #tomo2022! So much looking forward to it! I can't wait to meet old friends and make new ones with those I only know by name from papers or twitter! So many awesome developments! First,  I have to bicycle to catch my train to be on time for the 1st session in 5 hrs.
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Generation 3.3 laser phase plate in the microscope!
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Bram Koster retweeted
Fantastic work by PhD student @EmmaCouves! A real team effort from @scott_d_gardner @TomasVoisin @jasminebickel @pstansfeld @TateScience @imperialcollege @ICL_Receptors
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This week's release includes tomograms of #SARSCoV2 spike-bearing virus-like particles in an experiment which captures various #Covid #Spike #Protein intermediates! EMDB: ebi.ac.uk/emdb/EMD-24601 Paper: doi.org/10.1126/sciadv.abo31…
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No motion correction was applied yet. We further demonstrate effects of the probe size and much more. Manuscript: doi.org/10.1038/s41592-022-0… Raw data on EMPIAR will be available very soon e.g. EMPIAR-11034 4/4
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