@KralJan

MD, PhD, MSc, MBA at @FnMotol | Interests in #IBD, #Endoscopy, #LiverDiseases, #BariatricEndo, #AI, #3DPrinting - https://xitter.cf/t.co/ROG5kRobku, #ESGE SoMe WG

 Prague, Czech Republic
linkedin.com/in/jan-král-6a61b91b
Joined September 2010
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That was #LUCID2026 in Chicago! 🔥 Great days of advanced endoscopy, hands-on training, inspiring discussions and amazing people. 🩺🔬🤝 Proud to be part of it and share our experience in therapeutic and bariatric endoscopy. 🌎 #Endoscopy #Gastroenterology #MedEd #GiTwitter
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🧩 Phenotype-driven management of #EoE at #UEGWeek2026 💊 PPI, topical steroids or diet 🔄 Switch therapy if needed 🎯 Dilatation for strictures 💉 Dupilumab for selected patients Treatment tailored to phenotype. 👌 @my_UEG #MedTwitter #MedEd
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🔍 Key updates in EoE diagnosis presented at #UEGWeek2026: 🧪 ≥15 eos/hpf + symptoms 🔬 At least 6 biopsies from ≥2 esophageal levels 🎯 Target visible abnormal. ❌ Routine gastric & duodenal biopsies no longer mandatory Simple rules, better diagnosis. @my_UEG #GiTwitter
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💊 Should corticosteroids be discontinued before surgery? 📊 Data presented at #UEGWeek2026 suggest fewer organ space SSIs after discontinuation, although study heterogeneity remains an important caveat. An interesting ✉️ for clinical practice! 🔬 #GiTwitter #MedEd @my_UEG
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🔥 What has changed in #diverticulitis management from 2018 → 2026? Less routine antibiotics, more individualized care, and important changes in recurrent disease and post-abscess management. 📚🔄 Great guideline update at #UEGWeek2026! 👏 @my_UEG #MedTwitter #Guidelines
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Jan Král retweeted
ESGE@ESGE_newsOct 19
Missed out on a chance for a HOT spot at #UEGWeek? Tomorrow (Tuesday) walk-in sessions are available at 10:00 and 12:30. Full details here: esge.com/api/live/resources/…
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🔥 Hands-on time at #UEGWeek2026! 🙌 From guidelines to real practice. Learning, testing and sharing the latest techniques in endoscopy at the ESGE Hands-On Area. 💪 @my_UEG @ESGE_news #MedTwitter #Endoscopy #GIEndoscopy
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🔥 Excellent session on Emergencies in Upper GI at #UEGWeek2026! Great practical insights on managing refractory and recurrent GI bleeding and where OTSC fits in the algorithm. 🩸📎 @my_UEG #MedTwitter #Endoscopy #GIbleeding
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🍽️ Nutrition remains the foundation of obesity treatment. Assess → 🎯 Set goals → 🥗 Individualise → 💊 Combine → 🔄 Maintain. Simple, pragmatic and long-term. 💪 #UEGWeek2026 #MedTwitter #Obesity @my_UEG
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💊🚀 The obesity pharmacotherapy pipeline is exploding! From GLP-1 ➡️ GIP/GLP-1 ➡️ GLP-1/glucagon ➡️ even triple agonists 🔥 The next generation of obesity drugs is already coming.📈 Exciting overview at #UEGWeek2026 🇪🇸 @my_UEG #MedTwitter #Obesity #GLP1
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🎯 BMI doesn’t tell the whole story! 📏 Fat distribution matters especially visceral and abdominal fat. 🔥 Visceral fat is strongly linked to metabolic and liver risk 🫀🩺, even in patients with a “normal” BMI. #UEGWeek2026 🇪🇸 in Barcelona! @my_UEG #MedTwitter #Obesity
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⚠️ Key message from #UEGWeek2026: TIPS at the right time can be lifesaving. 🩸 From pre-emptive TIPS in high-risk patients to rescue TIPS and secondary prophylaxis. ✅ Timing and patient selection are key. @my_UEG @LiverFellow #MedTwitter #PortalHypertension #Endoscopy
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⚠️ Surgical risk in cirrhosis is not only about liver function, the type of surgery matters. 🏥 From low-risk procedures to high-risk open abdominal and cardiothoracic surgery: choose wisely❗️ #UEGWeek2026 #MedTwitter #Cirrhosis #Hepatology @my_UEG @LiverFellow
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How good are we at predicting surgical risk in patients with cirrhosis? 🎯 From Mayo to VOCAL-Penn and S-RISC — models are getting better, but clinical judgement still matters. #UEGWeek2026 #Cirrhosis #Hepatology #MedTwitter @LiverFellow @my_ueg
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🌍 WHO issues its first global guidelines on child & adolescent obesity. 📈 170M aged 5–19 lived with obesity in 2024. 🧒 Lifestyle care is key; 💊 meds & 🏥 surgery may be considered for selected adolescents. 🔗 tinyurl.com/r776j63u #MedTwitter #GiTwitter #MedEd @WHO
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Jan Král retweeted
ESGE@ESGE_newsOct 9
Would you give a promotility agent to a patient when dealing with a foreign body? Host @iangralnek & guest Henriette Heinrich agree on their approach. For more practical tips & tricks from their podcast search... ➡️➡️ Endoscopy Unplugged ⬅️⬅️ ...wherever you get your podcasts!
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Jan Král retweeted
ESGE@ESGE_newsOct 2
✨In case you missed the October ESGE eNewsletter it features: 🔹Abstracts opening 🔹Applications for Research Camp & ESGE-PENTAX Research Grant close soon 🔹ESGE at UEG Week 🔹ESGE Academy Video Journal #6 🔹EU-ENDOHEP survey closing soon … & more! 👉shorturl.at/DtNTg
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GLP1 use may result in about 1 extra case of NAION for every 5,000 people treated for a year. I break down the numbers and more in this week's #substanceovernoise: read.michaelalbertmd.com/p/d….
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🔥 Can endoscopic #obesity therapy target both anatomy AND appetite hormones? 🧠 GFMA targets the ghrelin-producing fundus before ESG 🪡. First-in-human sequential GFMA→ESG trial 📚tinyurl.com/3hcyhz32 #GITwitter #Endoscopy #MedEd #MedTwitter @ESGE_news @ASGEendoscopy
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📉 GFMA alone achieved 7.7% TBWL at 6 mo. ✅After ESG 🪡, TBWL reached 20.0% at 12 mo and 22.5% at 18 mo 🔥. ✅Ghrelin fell 462→255 pg/mL 🧪 at 6 mo, while nutrient tolerance dropped 57% by 18 mo 🥤. No serious AEs 🛡️ #GITwitter #Endoscopy
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🎯 Sequential GFMA→ESG targets hormonal 🧪 + mechanical/visceroceptive pathways 🧠, with 22.5% TBWL at 18 mo 📉 and improved eating behavior 🍽️. Promising, but this was a 10-patient, single-arm pilot 🔬. Larger controlled trials needed 📊 #GITwitter #Endoscopy
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