@LabPace

Group working on the development of tactics for chemical synthesis - through the use of organometallic reagents - with vistas to medicines synthesis.

 Turin, Piedmont
drugsynthesis.univie.ac.at
Joined August 2018
  • Tweets90
  • Following547
  • Followers1.2K
7Media
New research: 'Chemoselective homologative preparation of trisubstituted alkenyl halides from carbonyls and carbenoids' by Laura Castoldi, Vittorio Pace & Margherita Miele @LabPace #openaccess Included in ChemComm's 60th Anniversary Collection buff.ly/4j47Ll8
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Vittorio Pace (@LabPace) gives exclusive insights into “Designing New #SyntheticConcepts for Imparting Molecular Complexity with C-1 Sources” in our #Cheminar on Oct 14 (2 PM, CEST). Register here 👉 brnw.ch/21wNDrn (chaired by @Silicon_Martin) #metalchemistry @unito
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👩‍🔬👨‍🔬 In this Thieme #Cheminar, we will discover the path from #processchemistry to methodology development in metal-mediated chemistry and catalysis with @FleischerLab, @MatthewHorwitz1 and @LabPace. Join us on Oct 14, at 2 PM (CEST) 👉 brnw.ch/21wNj6L @TUB_Chem
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After the coffee break, Vittorio Pace is giving a presentation on the modification of sulfur platforms using nucleophilic C-1 releasing agents @LabPace #ISOCS30
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PaceLab retweeted
ICIQ@ICIQchem4 Jul 2024
#ICIQSeminar 🙌Thank you Prof. Dr. Vittorio Pace @LabPace from @unito for delivering a seminar about novel homologation reactions, complex architecture synthesis, and innovative fluoromethylation techniques 🔵Also thanks to our seminar sponsor @BASF_ES 🧵About the seminar 👇
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Homologation reactions for olefin synthesis (@GBD_Lab, @pengliu_group, @UChiChemistry, @Pitt_Chemistry, @LabPace): nature.com/articles/s44160-0… and nature.com/articles/s44160-0… (@NatureSynthesis).
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Now online: News & Views on the Article by @GBD_Lab @pengliu_group @UChiChemistry @Pitt_Chemistry nature.com/articles/s44160-0… ($) Homologation reactions for olefin synthesis by Laura Castoldi and Vittorio Pace @LabPace nature.com/articles/s44160-0… ($)
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Amazing Chemistry! cen.acs.org/synthesis/Hook-s…

Hook-and-slide strategy extends amides

A new homologation method can lengthen carbon chains by multiple atoms at a time

cen.acs.org
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Today we report a tunable amide homologation. Led by Rui @zhangrchem and Tingting (undergraduate), we demonstrate a "hook-and-slide" strategy. science.org/doi/10.1126/scie…
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Here's the full panel of the invited and keynote speaker @RSEQUIMICA @SCIorganica @SciGiovani @SocChimIta sisoc2024.unito.it/speakers
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Wittig/B─H insertion reaction: A unique access to trisubstituted Z-alkenes (@ScienceAdvances): science.org/doi/full/10.1126….
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Explore our 2023 Pioneering Investigators and HOT Articles collections. Now including 'Highly chemoselective homologative assembly of the α-substituted methylsulfinamide motif from N-sulfinylamines' by @LabPace #openaccess buff.ly/3rkxsrC
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Finally printed out @Wiley_Chemistry! A big thank to all the Authors of the 24 chapters who depicted the current state-of-the-art of Homologations in Synthesis. onlinelibrary.wiley.com/doi/…
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A unified strategy for the synthesis of aldohexoses by boronate assisted assembly of CH2X2 derived C1-building blocks by Hirschhäuser and colleagues from U. of Duisburg pubs.rsc.org/en/content/arti…

A unified strategy for the synthesis of aldohexoses by boronate assisted assembly of CH2X2 derived...

A synthetic strategy for all aldohexoses with individually addressable protecting groups from dihalomethane C1-units is reported. The underlying synthesis

pubs.rsc.org
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Our new study on the homologation of N-O bonds is now out in Chemical Science Base-mediated homologative rearrangement of nitrogen–oxygen bonds of N-methyl-N-oxyamides - pubs.rsc.org/en/content/arti… Thanks to @unito @dipchim @univienna

Base-mediated homologative rearrangement of nitrogen–oxygen bonds of N-methyl-N-oxyamides†

Due to the well known reactivity of C(O)–N functionalities towards canonical C1-homologating agents (e.g. carbenoids, diazomethane, ylides), resulting in t

pubs.rsc.org
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OMCOS dinner @OMCOSBoard Awesome conference, organization, and dinner! @ArtOxiZymes @LabPace @EvaHeviaGroup @BessetTatiana @CornellaLab @yorimitsu_lab #peterkündig #omcos21
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Attending to Vittorio pace @LabPace interesting conference just before @prsalamanc thesis defense, good luck!
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Very happy to share our recent (and my first 🙂) book chapter on "Transition‐Metal‐Free Reactions of Amides by Tetrahedral Intermediates" just published in Amide Bond Activation. Thanks @LabPace and the Editor (M. Szostak) for this opportunity! onlinelibrary.wiley.com/doi/…

Transition‐Metal‐Free Reactions of Amides by Tetrahedral Intermediates

Although conceptually intuitive, adding carbon nucleophiles to amides en route to carbonyls and amines remained elusive for ...

onlinelibrary.wiley.com
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Check out this Communication Article... #openacess 🔓 By Vittorio Pace and first author Margherita Miele @LabPace Read their article here ⬇ 🔗 rsc.li/39swvnP
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2-methylene in one shot. Nice job Raf and Malik. Thanks @dipchim @unito @univienna
Angewandte Chemie@angew_chem14 Oct 2021
Consecutive and Selective Double Methylene Insertion of Lithium Carbenoids to Isothiocyanates: A Direct Assembly of Four-Membered Sulfur-Containing Cycles (Pace) @LabPace @univienna #openaccess onlinelibrary.wiley.com/doi/…
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