@LabPetry

microtubule architects, cellular engineers, fireworks of life, biochemists, scientists, teamwork, 🌈

 Princeton, NJ
scholar.princeton.edu/petrylab/home
Joined May 2018
  • Tweets682
  • Following476
  • Followers1.8K
81Media
Harry Higgs and I want to hear from you! Submit your abstract by May 18 for one of many short talks and present your poster at our #FASEB #cytoskeleton conference in MA. Save your space: hubs.ly/Q03k9zp60#CSDSRC
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Interested in actin, intermediate filaments and microtubules? Then this FASEB conference is for you – the only one in North America focused on the cytoskeleton with fantastic speakers. July 13-17 2025 in Southbridge MA. #cytoskeleton #FASEB #CytoskeletalStructureDynamicsFunction
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Congratulations @meisam_zaferani and Ryungeun! We are proud of you.
Meisam Zaferani@meisam_zaferani17 Jan 2024
Our work is now online at @PNASNews! 🥳 pnas.org/doi/10.1073/pnas.23… This was a fantastic collaboration with my teammate, Ryungeun Song. A big shout-out to Howard Stone and @LabPetry for their superb mentorship throughout this journey. @omenndarlingbio @EPrinceton @PrincetonMolBio

Building on-chip cytoskeletal circuits via branched microtubule networks | PNAS

Controllable platforms to engineer robust cytoskeletal scaffolds have the potential to create novel on-chip nanotechnologies. Inspired by axons, we...

pnas.org
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Just when you think you have it all, Venecia Valdez and team from @RuiZhangWUSTL and @LabPetry prove us wrong: HURP facilitates spindle assembly by stabilizing microtubules and working synergistically with TPX2 biorxiv.org/content/10.1101/…
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Follow this thread to get the full story by @meisam_zaferani with Ryungeun Song from Howard STone's lab and @LabPetry on cytoskeletal circuits, our newest development:
Meisam Zaferani@meisam_zaferani3 Oct 2023
Have you ever seen a microtubule (MT) diode?🤯 Exciting news! 🎉 My first postdoc publication is out! With Ryungeun Song, Howard Stone, and @LabPetry, we combined microfluidic, nanofabrication, and branched MT networks to build cytoskeletal circuits. ift.tt/U8pt3hO
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Congrats to @JodiKraus1 and team @LabPetry! And thanks for @TrendsBiochem for the invitation!
Trends in Biochemical Sciences@TrendsBiochem24 Jul 2023
Available now - the Review "#Microtubule nucleation for spindle assembly: one molecule at a time" from @JodiKraus1, @AcoAlfaro, @BernieGouveia, and @LabPetry. #yTuRC #spindleassemblypathway #spindleassemblyfactors #MTnucleation Read it here 👉 authors.elsevier.com/a/1hSWP…
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Terrific work by Changmiao Guo and Ray Alfaro-Aco from @TatyanaPolenova and @LabPetry: Structural basis of protein condensation underlying branching microtubule nucleation nature.com/articles/s41467-0…

Structural basis of protein condensation on microtubules underlying branching microtubule nucleation

Nature Communications - TPX2 is a key factor stimulating branching microtubule (MT) nucleation. TPX2 forms condensates on MTs critical for branching. In this work, the authors report the...

nature.com
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Our article is featured here: nature.com/collections/hhfig…. Thank you @NatureComms !

Structural biology, biochemistry and biophysics

On this page, we highlight some of our most exciting recently published articles in the areas of biochemistry, biophysics, mass spectrometry and structural ...

nature.com
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Our paper on chromosomal branching nucleation and spindle assembly is now out! Many new results in the final version: doi.org/10.1038/s41467-023-3… Great work together with @SagarSetru, @shaevitz, @LabPetry, and Howard Stone.
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Opportunity pls #retweet: Josh @shaevitz and I are looking to hire a postdoc to work on an exciting new direction for us. A combination of wet lab, experimental design, and 3D image analysis to answer fundamental questions about the mitotic spindle. Interested? Shoot me an email!
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Farewell dinner with@LabPetry: Our two senior thesis students Haley Tran and Mike Ruttlen received straight A's - congrats! We wish Haley and Mike well in their next career stage and are awaiting Mike's #NFLDraft next year!!! <= 🏈 &🧪 !!!
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This paper is now officially out: Augmin is a Ran-regulated spindle assembly factor: jbc.org/article/S0021-9258(2… Congrats @JodiKraus1 and @sophiembtravis and alumni @MattKingLab from @LabPetry

Augmin is a Ran-regulated spindle assembly factor

Mitotic spindles are composed of microtubules (MTs) that must nucleate at the right place and time. Ran regulates this process by directly controlling the release of spindle assembly factors (SAFs)...

jbc.org
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We hope this will be useful for many! Venecia Valdez and@LilaNeahring outdid themselves with this review, in a fantastic collaboration between @DumontLab and @LabPetry nature.com/articles/s41580-0…

Mechanisms underlying spindle assembly and robustness

Nature Reviews Molecular Cell Biology - Spindle assembly during cell division requires self-organization of microtubules into a complex, bipolar structure that directs the movement of chromosomes....

nature.com
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Proud of Venecia!
Princeton MolBio@PrincetonMolBio17 Apr 2023
Congratulations 🎉 to Venecia Valdez, a fifth-year graduate student in the @LabPetry, on her selection to receive a Charlotte Elizabeth Procter Fellowship bit.ly/41ynQpD for the 2023-24 academic year!
Venecia Valdez, a fifth-year graduate student in the Petry lab in the Department of Molecular Biology of Princeton University.

ALT Venecia Valdez, a fifth-year graduate student in the Petry lab in the Department of Molecular Biology of Princeton University.

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Congrats to @sophiembtravis and team from @RuiZhangWUSTL and @LabPetry on the augmin structure! Also congrats to @PfefferCryoLab and @lchangpurduebio for their structural work!
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And very nice preview that summarizes the three works by S. Manka: nature.com/articles/s41467-0…

Structural insights into how augmin augments the mitotic spindle

Nature Communications - Cell division critically requires amplification of microtubules (MTs) in the bipolar mitotic spindle. This relies on the filamentous augmin complex that enables MT...

nature.com
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Here is the link to the paper: nature.com/articles/s41467-0…

Integrated model of the vertebrate augmin complex

Nature Communications - Many microtubules in the mitotic spindle are made through microtubule branching. Here, the authors report a structural model of the augmin complex and insights into its role...

nature.com
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Well done @JodiKraus1 and @sophiembtravis !
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Replying to @iaincheeseman
@iaincheeseman @centromellone @DivIDE_2023 @MCDB_Yale @YaleCellBio @ctmurphy1 @J_Cell_Sci @Spo11Rulz @LabPetry @FritzLaylin @LuskingL @JoeHowardd @LacefieldLab Please retweet and amplify 🙏🏿
Kabeche Lab@KabecheLab23 Mar 2023
#Celldivision fans: check out the 2023 BAMM meeting!! This awesome one day free conference will host an exciting set of speakers from the New England area! This year it will be hosted at @Yale University! Submit a short abstract by April 1st for an opportunity to give a talk.
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Quad-lab (!) review which connects capillarity/physics with condensates/biology by @BernieGouveia and Yoonji Kim, mentored by @brangwynnelab, Howard Stone's Lab, @shaevitz and @LabPetry. Capillary forces generated by biomolecular condensates pubmed.ncbi.nlm.nih.gov/3607…
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