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Puhar Lab

@LabPuhar

We study infection and inflammation in the gut with focus on the endogenous danger signal extracellular ATP.

 Belfast, UK and Umeå, Sweden
mims.umu.se/groups/andrea-puhar.html
Joined February 2020
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  • Followers409
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Photo by Puhar Lab (@LabPuhar)Photo by Puhar Lab (@LabPuhar)Photo by Puhar Lab (@LabPuhar)Photo by Puhar Lab (@LabPuhar)Photo by Puhar Lab (@LabPuhar)Photo by Puhar Lab (@LabPuhar)Photo by Puhar Lab (@LabPuhar)Photo by Puhar Lab (@LabPuhar)Photo by Puhar Lab (@LabPuhar)Photo by Puhar Lab (@LabPuhar)
📣 Job Alert: Exciting Career Opportunities at MIMS! 🌟 Join us at the Swedish node of @NordicEMBL , @mims_umea, @umeauniversity! We're hiring: Group Leader in Infection Medicine, several Postdoctoral Researchers, and Project Administrator (event focus). umu.se/en/mims/career-and-ed…

Work With Us

umu.se
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We're looking for an Assitant Professor in Microbiology to join us @tcdgenmicro! Come and join our growing team. tcd.ie/microbiology/research… tcd.ie/hr/vacancies/ Job ID: 037876. Closes 31st January
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1/8 Publication Alert! Delighted to share the publication of a collaboration by Gerben Marsman (@zychlinsky lab @mpiib_berlin) and @xuhui_zheng (former PhD student in my lab) et al detailing how Histone H1 kills MRSA (cell.com/cell-reports/fullte…).
Histone H1 kills MRSA

Histone H1 kills MRSA

Marsman et al. detect histone H1 in MRSA in human abscesses and demonstrate that it kills MRSA under physiological conditions. They identify through selective evolution and a genome-wide screen that...

cell.com
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Puhar Lab retweeted
Abcam (@abcam) profile picture
Abcam
@abcam12 Nov 2024
Replying to @InflammaZoom
@InflammaZoom, the free webinar series for #innateimmunity and #inflammasomebiology researchers, returns November 21 with talks from Serge Mostowy @LSHTM @mostowylab and @PrajwalGurung @uiowa. Register here to join us: events.abcam.com/AnYVL?rt=Ql…
Image from Abcam (@abcam)
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Antibacterial compounds against non-growing Uropathogenic Escherichia coli identified via an HTS by the Chemical Biology Consortium Sweden, @umeauniversity. Led by the Tenson lab @unitartu, contributions from @LabPuhar and us at @lunduniversity. biorxiv.org/content/10.1101/…
Antibacterial Compounds Against Non-Growing and Intracellular Bacteria

Antibacterial Compounds Against Non-Growing and Intracellular Bacteria

Slow- and non-growing bacterial populations, along with intracellular pathogens, often evade standard antibacterial treatments and are linked to persistent and recurrent infections. This necessitates...

biorxiv.org
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📢 #EESMicrobiology is now open for registrations! Explore cutting-edge topics in #microbiology and discover the new approaches and technologies that can revolutionise the field's future. Submit your abstract and register to participate!

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A great review on the "Loss of tolerance to dietary proteins: From mouse models to human model diseases" from SMI member Nadine Cerf-Bensussan: onlinelibrary.wiley.com/doi/…
Image from Society for Mucosal Immunology (@socmucimm)
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It is out! 🚨 Phosphorous-free bacterial lipids can switch between pro- and anti-inflammatory depending on context!🔬 #Immunology #LipidBiology @PelegrinPablo @inflammasomelab A big thanks to the reviewers and editors. It was a laborious but smooth process🥳
Cell Reports (@CellReports) profile pictureCell Reports@CellReports27 Sep 2024
Ornithine lipid is a partial TLR4 agonist and NLRP3 activator dlvr.it/TDlKJF
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Come join our fun community! Reach out to us with any question on this exciting project
This Post is from an account that no longer exists. Learn more
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Online now - the Review "The #InositolPhosphate signalling network in physiology and disease" from Seyun Kim, Rashna Bhandari, Charles Brearley, and Adolfo Saiardi. #InsP #PPInsP #kinase #phosphatase #cofactor #bridge Read it here 👉 authors.elsevier.com/sd/arti…
Image from Trends in Biochemical Sciences (@TrendsBiochem)
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Job Alert! The Aramburu Lab @mims_umea @NordicEMBL is looking for a postdoc. If you are interested in discovering new #microproteins in innate immune cells and have a background in computational or proteomics, Apply or contact me. umu.varbi.com/what:job/jobID…
Postdoktor i proteinforskning i medfödda immunceller

Postdoktor i proteinforskning i medfödda immunceller

Institutionen för molekylärbiologi söker en postdoktor för en tidsbegränsad anställning på två år motsvarande heltid med start 1 december 2024 eller enligt överenskommelse. Aramburu-laborato

umu.varbi.com
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#France2030 [SAVETHEDATE] Le Laboratoire d’Excellence en Biologie Intégrative des Maladies Infectieuses Émergentes @IbeidLabex organise la conférence internationale "Adapting to Change : Emerging Infectious Diseases in a Shifting Climate" du 16 au 18 octobre 2024 @institutpasteur
Image from ANR - Agence nationale de la recherche (@AgenceRecherche)
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Wow!
Ivan Ahel Lab (@IvanAhelLab) profile pictureIvan Ahel Lab@IvanAhelLab8 Sep 2024
Our new paper demonstrating reversible ubiquitylation of DNA and RNA: embopress.org/doi/full/10.10…
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Thrilled to announce that we have a postdoctoral position available to join the lab and investigate persistent Shigella infection! Do reach out if interested! Deadline: October 3rd Link: shorturl.at/Ndx6X Please retweet! @kingsmedicine @KCLImmunoMicro
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We are hiring! Together with @__jphilipp, we are looking for two motivated PhD candidates to investigate fundamental immune mechanisms of bacteria against bacteriophages in the framework of the DFG priority program @SPP2330! euraxess.ec.europa.eu/jobs/2…
Image from Marc Erhardt (@Salmo_Lab)
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Puhar Lab retweeted
T3SS (@T3SS2) profile picture
T3SS@T3SS230 Aug 2024
Gut bacterial type III secretion systems aggravate colitis in mice and serve as biomarkers of Crohn’s disease - eBioMedicine thelancet.com/journals/ebiom…
Gut bacterial type III secretion systems aggravate colitis in mice and serve as biomarkers of...

Gut bacterial type III secretion systems aggravate colitis in mice and serve as biomarkers of...

These findings highlight the pathogenic significance of T3SSs in the context of CD and identify specific T3SS genes that could potentially function as biomarkers for diagnosing and monitoring the...

thelancet.com
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Puhar Lab retweeted
GeroldLab (@GeroldLab) profile picture
GeroldLab@GeroldLab31 Aug 2024
Here is the ad for position 1
Image from GeroldLab (@GeroldLab)
Image from GeroldLab (@GeroldLab)
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Puhar Lab retweeted
GeroldLab (@GeroldLab) profile picture
GeroldLab@GeroldLab31 Aug 2024
And here the ad for position 2
Image from GeroldLab (@GeroldLab)
Image from GeroldLab (@GeroldLab)
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Obesity-enriched microbe promotes lipid absorption. Megamonas enterotype-like cluster is enriched in individuals w/obesity. M. rupellensis degrades myo-inositol, which inhibits fatty acid transport & promotes lipid absorption, causing obesity in mice cell.com/cell-host-microbe/a…
Image from Cell Host & Microbe (@cellhostmicrobe)
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Fishing for obesity-related gut microbiome enterotype. Highlight of work identifying an obesity-related enterotype-like cluster, Megamonas, and demonstrating its clinical relevance through cohort studies, mice, and cell experiments cell.com/cell-host-microbe/a…
Image from Cell Host & Microbe (@cellhostmicrobe)
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