Research lab of Dr. Stephen Waggoner. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer. @labwaggoner.bsky.social
Cincinnati, OH
Joined August 2018
- Tweets39.2K
- Following8.3K
- Followers13.5K
- Likes7.6K
Ridiculous: USG Policy for the use of Super Intelligence
Notice Number: NOT-OD-27-011
grants.nih.gov/grants/guide/…
Antigen-independent IgM BCR signaling intrinsically limits human IgM plasma cell differentiation, survival, and in vivo persistence by elevating basal calcium flux and restraining IRF4 and BLIMP1 induction
rupress.org/jem/article-abst… @JExpMed @seattlechildren
Multi-omics profiling of primary human B cells activated via distinct stimuli
nature.com/articles/s41467-0…
@NatureComms @BostonChildrens
Review @NatImmunol
Cytokine circuits in CNS homeostasis and disease
nature.com/articles/s41590-0…
Hydrogel for sustained and localized delivery of a regulatory T cell-inducing agent promotes bone regeneration @natBME @Harvard
nature.com/articles/s41551-0…
Microparticles released from ultraviolet-irradiated erythrocytes enhance anti-tumoural T cell immunity via TH1 cell adjuvant activity @natBME
nature.com/articles/s41551-0…
nature.com/articles/s41551-0…
Determinants of response to CAR T cell therapy in a multicenter, multi-trial cohort analysis of patients with lymphoma @NatureMedicine @DBedognetti
nature.com/articles/s41591-0…
Serine protease inhibitor A3 is a soluble SIRPα ligand that suppresses inflammation and antitumor immunity @NatImmunol
nature.com/articles/s41590-0…
NF-κB responses are functionally partitioned by enhancer architecture: phos-sensitive sites define a NF-κB-dominated latent enhancer compartment, whereas primed sites are embedded in broader networks of lineage-determining factors @ImmunityCP
cell.com/immunity/fulltext/S…
Taurine lowers inflammaging by regulating the NLRP3 inflammasome in macrophages @CellCellPress
cell.com/cell/fulltext/S0092… @VishwaDeepDixi1 @Yale
A granzyme-independent function of perforin as a direct executioner of cancer cell death through ferroptosis @CellCellPress
cell.com/cell/fulltext/S0092… @umichmedicine @harvardmed
@barrosolab @AlbanyMed #Zou #Lieberman
Lung neuroendocrine cancer induces immunosuppressive macrophages via serotonin to drive resistance to the T cell engager tarlatamab @Cancer_Cell
cell.com/cancer-cell/fulltex… 🇯🇵
Lifestyle-induced regulatory T cell fragility primes adverse events after immune checkpoint blockade @CellCellPress @OveracreLab @UPMCHillmanCC @ItzDipyama
cell.com/cell/fulltext/S0092…
Very excited to share our latest paper, out today in Cell, led by @ItzDipyaman! This project started out with a curiosity as to how and why irAEs happen. Even more peculiar is that WT mice never develop irAEs…and why was that?
cell.com/cell/fulltext/S0092…
Lifestyle-induced regulatory T cell fragility primes adverse events after immune checkpoint blockade @CellCellPress @OveracreLab @UPMCHillmanCC @ItzDipyama
cell.com/cell/fulltext/S0092…
Intron retention regulates STAT2 function and associates with immunotherapy response in lung cancer @ScienceMagazine @jacksonlab
science.org/doi/10.1126/scie…
Two proteins that permeabilize mitochondria promote cell death through distinct mechanisms @ScienceMagazine @MSKCancerCenter
science.org/doi/10.1126/scie…
science.org/doi/10.1126/scie…
The TCF-1-E-protein axis preserves stem-like Th17 identity and prevents autoimmune pathology @CellReports 🇨🇳
cell.com/cell-reports/fullte…
Review @CellRepMed
CNS targeted AAV gene therapies: Recent advances and clinical insights
cell.com/cell-reports-medici…
Deletion of Ctps1 in T cells prevents GVHD and reduces skin rejection @CellRepMed @Inserm 🇫🇷
cell.com/cell-reports-medici…
