Akhilesh Pandey Lab

Significant decrease in N-glycopeptides was seen in haptoglobin, ceruloplasmin and albumin among others. These site-specific glycopeptide changes may provide new biomarkers and insights into SRD5A3-CDG pathophysiology. Led by Anu Jain @Dr_Anu_Jain from our team.

This method enables detection of multiple clinically relevant markers at once in a single #FFPE section. It is concordant with IHC and offers new possibilities for multiplexed spatial biomarker resolution. Led by Kiran K. Mangalaparthi @mkirankumar89 and Daigo Gunji from our team

These extra findings (IGH rearrangements, TP53 loss, 1q gain, chromothripsis) can alter risk stratification and treatment decisions. Proximity mapping may improve diagnosis and enable more precise, mutation-guided therapy. Led by Richard Kandasamy @richardKumaranK from our team

Using targeted mass spectrometry-based measurement of all hemoglobin chains, we discovered that the levels of #hemoglobin mu chain are increased in patients with alpha thalassemia where the HBM gene is spared from deletion, indicating a compensatory role and #biomarker potential

We present a targeted strategy combining tandem mass tag multiplexing with SureQuant-based triggered MS/MS using super heavy TMT-labeled peptides as triggers, enabling robust quantitation of histone PTMs with improved analytical throughput #Singlecellproteomics

Excited to share our new study published in Blood Cancer Journal @BloodCancerJnl! Using @OlinkProteomics we profiled bone marrow plasma from #MultipleMyeloma & monoclonal gammopathy of undetermined significance patients to uncover specific protein signatures #MyelomaResearch

Congratulations to Kishore for presenting our glycoproteomics work in congenital disorders of glycosylation at the Ehlers Symposium & BMB Research Retreat at Mayo Clinic — and for winning a Best Poster Award! 🏆 Exciting recognition for outstanding science! @kilroykishore

Shoutout to Joel-Sean Hsu from our team for presenting our ongoing research on IMiDs in multiple myeloma at the Ehlers Symposium & BMB Research Retreat at Mayo Clinic. Grateful for the opportunity to share our work and connect with the community 🧑‍🔬🧪

Check out Dong-Gi Mun’s poster in applying super heavy TMT to single cells 🧫

Proud to present our studies on human brain peptidomics and terminomics by Hiroshi Nishida 🧠 #ASMS2025