A @CornellBME @weillinstitute research group studying cell structure, mechanics, and function. Tweets by Jan Lammerding & lab members. #nucleus #mechanobiology
Joined March 2022
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Hello! The Lammerding Lab @CornellBME and @weillinstitute is now on Twitter! Here is what you can expect from this account: highlights of our #mechanobiology work, pretty fluorescent images and videos, gushing over our team members, and more. Follow us!
Attending #BMEs2026 and want to learn more about nuclear #mechanobiology? Come and enjoy one of our lab‘s talks or posters, or visit us at the @CornellBME booth. See you in Orlando.
Mutations in the LMNA gene, encoding lamins A/C, cause severe dilated cardiomyopathy.
But what drives the disease?
Disrupted chromatin organization & gene regulation or mechanical damage to the nucleus?
Distinguishing these mechanisms is critical for developing new therapies.
Our findings suggest that targeting nuclear rupture and its downstream consequences could open new therapeutic avenues for LMNA cardiomyopathy!
THANK YOU to Noam Zuela-Sopilniak, Julien Morival, our collaborators & funders: @NIH (NHLBI, @NIH_NIAMS, NIGMS) & the Mills family.
6/7
Read the full article at:
ahajournals.org/doi/10.1161/…
Can protecting the cell nucleus prevent heart failure—even when the genetic defect remains?
Our new study in @CircRes suggests it can!
We identify nuclear envelope rupture as a key driver of LMNA-related cardiomyopathy.
doi.org/10.1161/CIRCRESAHA.1…
#Mechanobiology, #lamins, #LMNA
1/7
Looking for a faculty position combining research in fundamental cell and molecular biology with therapeutic discovery?
Join our amazing faculty at the @weillinstitute at @Cornell University in Ithaca, New York.
academicjobsonline.org/ajo/j…
Apply by Nov. 15!
Please share!
Lammerding Lab retweeted
Undergrads! - thinking about what’s next after your B.S.? Explore how @CornellEng ’s one-year Master of Engineering in biomedical engineering can help you turn engineering skills into real-world healthcare solutions. Register for an upcoming info session: duffield.cornell.edu/bme/men…
Lammerding Lab retweeted
Where can an M.Eng. take you? Just ask the Class of 2016. Ten years after graduation, alumni are leading in medical devices, pharma, robotics, consulting, bioinformatics, entrepreneurship and more, while staying connected and mentoring the next generation. news.cornell.edu/stories/202…
ALT Alumni from Cornell's 2016 cohort of biomedical engineering Master of Engineering program returned to Ithaca during for their 10-year reunion.
ALT Alumni from Cornell's 2016 cohort of biomedical engineering Master of Engineering program returned to campus during for their 10-year reunion.
ALT From left: Dae Hee Yun, M.Eng. ’16 with his wife and daughter; and Crystal Shuo Shan, M.Eng. ’16, and Gaurang Dimri, M.Eng. ’16, with their child.
ALT From left: Emily Christie, M.Eng. '16, Diana Rudz, M.Eng. '16, professor Jonathan Butcher, and Zachary Woods, M.Eng. '16.
Lammerding Lab retweeted
We have a new assistant professor position in the @weillinstitute on Biomedical and Translational Sciences. Come join us! apps.hr.cornell.edu/recruiti…
Lammerding Lab retweeted
How can engineering educators better teach teamwork? Professor Alexandra Werth has received a $499,999 @NSF grant to develop a framework for teaching collaboration, conflict management, and feedback. news.cornell.edu/stories/202…
Lammerding Lab retweeted
Advice for new PhD students: choose a mentor who is committed to your training, not just your project. The most important product of your PhD - even more important than the science - is you, a newly trained scientist.
Lammerding Lab retweeted
Forever grateful to Beckie ’82 and Neil Robertson ’82 for endowing the Michael Shuler Clinical Immersion Program in Biomedical Engineering, helping students connect classroom learning with firsthand experiences in patient care and clinical problem-solving.
news.cornell.edu/stories/202…
ALT Beckie Robertson, Michael Shuler, Neil Robertson
Lammerding Lab retweeted
🧵 What if one reason fertility declines with age isn’t just genetic-but mechanical?
Thrilled to share our new paper in @NatureCellBio:
Elevated contractility drives implantation failure in mouse embryos from aged females… here’s what we found 👇
1/11
nature.com/articles/s41556-0…
Interested in nuclear mechanobiology and want to know what some of the big open questions are in the field?
Read our recent editorial with input from >15 leading experts in the field, along with a list of review articles on nuclear #mechanobiology:
tandfonline.com/doi/full/10.…
Lammerding Lab retweeted
And finally—a bit of personal news:
🔬 I’m on the faculty job market this year!
I’m looking for tenure-track opportunities where I can build a lab at the intersection of developmental biology, mechanobiology, reproductive biology & aging.
🧵 What if one reason fertility declines with age isn’t just genetic-but mechanical?
Thrilled to share our new paper in @NatureCellBio:
Elevated contractility drives implantation failure in mouse embryos from aged females… here’s what we found 👇
1/11
nature.com/articles/s41556-0…
Lammerding Lab retweeted
I am happy to announce that I will be opening my own lab as a professor at @UQTR on September 1!
Follow the launch 🚀 of our lab at caillierlab.com 🔬, where we will study how cells sense, generate forces, and migrate through complex environments!
Lammerding Lab retweeted
The US National Science Foundation will award about 30% fewer new research grants this fiscal year than in the last one, Nature has learnt.
go.nature.com/4bVmnla
