Making biotech more legible. Hosted by @shmkdbr

Joined October 2025
Replying to @shmkdbr
@shmkdbr and I discuss the edges of biotech from DeSci to human evidence to where biotech is intersecting with culture with the emergence of looksmaxxing.
Ep 5: Creative Destruction in Biotech with @shelbynewsad from @CompoundVC Chapters 07:21 Platform vs Product 14:25 Creative Destruction in Biotech 23:54 Decentralized Science and Crypto 30:35 Careful with Gray Label Peptides 35:34 Accelerating Human Clinical Trials 45:36 The Role of Virtual Cell Models 50:01 The Evolution of Bio-Manufacturing 53:34 Consumer Biotech: The Next Frontier 58:51 Implications of Looksmaxxing
3
9
2,310
Being in SF this week has made me realize how underappreciated Biotech really is, two large events, Substack debate and Hamilton society have a Biotech focus yet very few founders and VCs I meet at all the parties and events working on/investing in Biotech. The technology is there and its in the zeitgeist and people care about it and it is obviously going to have a massive impact on our future There is so much alpha in Biotech right now, especially compared to AI, on the founder and VC side its insane how its not being exploited
17
15
3
193
15,643
Legible retweeted
anabology
@anabology10 Dec 2025
Lfg - learn about Gilbert Ling & Aion here!
Ep 4: Bioelectricity with @anabology Rethinking cell membranes, origins of MRI, building Med Beds, and more 00:00 - Background and Bioelectricity 10:19 - Gilbert Ling 28:27 - Raymond Damidian 45:23 - What is Structured Water? 49:32 - Are Small Molecule Approaches a Dead End? 59:30 - Building Aion Biosciences in St Louis. MO 01:05:12 - Consciousness and Origin of Life 01:11:46 - Cosmetics Sidequest (skin.food)
10
7
1
146
22,102
Unc has still got it Jake (@SynBio1) talks about the current state of biotech, and more importantly - where the hell AI really fits into biotech. Interesting listen
Ep 3: Read, Write, Grow with @SynBio1. We discuss the 100 year vision for synthetic biology, biotech's product problem, biomanufacturing, and more. 00:00 - Jake Wintermute鈥檚 Journey in Biotech 08:32 - The Vision for Synthetic Biology 15:59 - Bio-Manufacturing as a Gateway 18:48 - Platform vs Product Companies in Biotech 25:39 - The Role of AI in Drug Discovery 29:34 - Addressing Bottlenecks in Clinical Trials 31:25 - Communicating Synthetic Biology 38:35 - Consumer-Facing Biotechnologies
1
1
8
814