Neuroscientist using brain signals to identify novel biomarkers of brain illnesses
Stanford, CA
Joined March 2020
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Happy to announce our latest paper out on Nat Mental Health, where we show that TMS restores functional connectivity and cognition in a cognitive biotype of depression!
nature.com/articles/s44220-0…
Thank you to all the co-authors: @AlisaMOlmsted, @divyardotdotn, @yossiberlow, @mmadore & others not on here🙏
Thank you to my mentor, @LMWilliams_PhD and @Stanford_PMHW who made this possible!
Leonardo Tozzi retweeted
New! Our study in @NatureMentalHealth reveals early functional brain & behavioral improvements in a cognitive biotype of depression after TMS, advancing precision mental health, with amazing @LeonardoTozzi1 @mmadore @NoahSPhilipMD Kelvin Lim Paul Holtzheimer
rdcu.be/dMQif
Happy to announce our latest paper out on Nat Medicine, where we use a small set of rest and task fMRI features to cluster participants w. anxiety/depression and relate these clusters to symptoms, behavior and treatment response!
nature.com/articles/s41591-0…
Thank you to all the co-authors: @warmxue, @pineurosci, @AlisaMOlmsted, @EmilyZhai2, @EstherAnene_, @BHoltGosselin, @Sarah_Chang_, @DrMKorgaonkar, @theAJNR_EIC , @GotlibLab & others not on here🙏
Thank you to my mentor, @LMWilliams_PhD and @Stanford_PMHW who made this possible!
Leonardo Tozzi retweeted
Thrilled to share our paper identifying a cognitive biotype of depression jamanetwork.com/journals/jam…. Results show the promise of precision psychiatry for expediting tailored treatments. Amazing authors @Stanford_PMHW @LeonardoTozzi1 @Rachel_Hilton1 @AlisaMOlmsted @DrMKorgaonkar
To all computational neuro people: I have a simple task where ppl navigate a hidden maze and have to "discover" the right path through trial and error. I want to do modeling of choices/trials. What would be a good model? Smth with reward learning? 🤔
@ArielleKeller , maybe you know? It's the webneuro maze task, we are trying to model it computationally, somehow.
Fantastic opportunity to work with a stellar mentor!
I am recruiting my first PhD student on the @ERC_Research funded research project DECOMPOSE at the @UniPadova. The focus of the project is identifying active ingredients of psychological interventions for severe mental disorders.
cordis.europa.eu/project/id/…
Fantastic study with a brilliant design!
SPIKED: Stanford Placebo vs Intraop Ketamine Evaluated for Depression. We masked ketamine with surgical anesthesia in depressed patients. Full details now published, peer review pending. Huge antidepressant response in both groups. @TheresaLii 1st auth
bit.ly/3LMAueK
Leonardo Tozzi retweeted
Got one into neuron! LMK if you don't have access, but here's the link sciencedirect.com/science/ar…, and I'll explain why I think we're onto something big below:
Leonardo Tozzi retweeted
Belated post – I’m excited to share my recently published first-authored manuscript in @BiologicalPsyc1 GOS that I worked on with wonderful co-authors @LeonardoTozzi1, Carolina Ramirez, Ian Gotlib (@GotlibLab), and Leanne Williams (@Stanford_PMHW) sciencedirect.com/science/ar…
I'm a causality newbie! I have 2 time series (A&B) and A causes B. My hypothesis is: in group 1 the causal link between A and B will be on avg lower vs group 2. Need to do a power analysis to detect this. Thinking of simulating but not sure how. Maybe @KordingLab has pointers? 😅
Leonardo Tozzi retweeted
🧠New article introducing several approaches to regularizing canonical correlation analysis (CCA) that take the underlying data structure into account, by Drs. Elena Tuzhilina, @LeonardoTozzi1 and Trevor Hastie
journals.sagepub.com/doi/10.…
#fMRIdata #neuroimaging #Mentalhealth
Happy to announce our new publication on NeuroImage!
Introducing group regularized canonical correlation analysis, an extension of CCA modeling properties of functional connectivity within brain networks to avoid overfitting and inflated results doi.org/10.1016/j.neuroimage…
Leonardo Tozzi retweeted
Learn more about the use of functional connectivity to map brain function to self-reports of negative emotion in a recent publication by Drs. @LeonardoTozzi1, Elena Tuzhilina, Matthew Glasser, Trevor Hastie & Leanne Williams 🧠
#MentalHealthAwarenessMonth sciencedirect.com/science/ar…
Our new paper is out! We did a meta-analysis (618 MDD vs 683 controls) of functional connectivity in and between DMN subsystems in MDD and tested its association with rumination in an independent sample 115 unmedicated anxiety/depression vs 48 controls).
doi.org/10.1016/j.nicl.2021.…