@LinahuertaM

#PedsEndo, #T1D #diabetesresearch | #ClinicalTrials @PennStHershey #psu @penn_state, #NutritionScience #researcher #T1Dstaging. Tweets are my own

 Hershey, PA
pennstate.pure.elsevier.com/en/persons/lina-huerta-saenz
Joined January 2019
  • Tweets1.1K
  • Following953
  • Followers530
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Lina Huerta-Saenz, MD, FAAP retweeted
Eric Topol
@EricTopolOct 25
What is "medical superintelligence" and why are we so far away from the concept? open-access bmjdigitalhealth.bmj.com/con…
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Lina Huerta-Saenz, MD, FAAP retweeted
Berci Meskó, MD, PhD
@BerciOct 22
I really admire figures that can describe a concept better than long manuscripts. This image is from an excellent paper in Nature by Vivek Subbiah about the future of evidence-based medicine and the design of clinical trials, all inspired by the rise of artificial intelligence. This is the era of the next generation of 'deep' medicine. "Current paradigms must be continuously challenged by emerging technology and by all stakeholders (the new generations of scientists, physicians, the pharma industry, regulatory authorities and, most importantly, patients). Disruptive innovation should lead to every clinical site being a research site, with all necessary quality checks and research as part of the standard of care. My personal view is that every major disease needs a ‘Moonshot’ program and every rare disease should have an ‘Operation Warp Speed’—both with clearly identified, sustainable goals to improve population health and address equity, diversity and global access to therapies. Methodological advances and future AI-based analyses of all data will provide deep evidence to realize the goal of personalized medicine— that is, to offer the right treatment to the right patient at the right time." The paper: nature.com/articles/s41591-0…
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Lina Huerta-Saenz, MD, FAAP retweeted
Diabetologia@DiabetologiaJnlOct 14
BAF60A preserves beta cell identity and insulin secretion via ISL1. BAF60A loss promotes dedifferentiation, while overexpression improves beta cell function #Diabetes #BetaCells #Epigenetics #DiabetesResearch link.springer.com/article/10…
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#BreakthroughT1D #Espanol Amigos y #Latinx community con #T1D Compartan Esta informacion con la #ComunidadHispana afectada por #type1diabetes #Spanish
Breakthrough T1D
@BreakthroughT1DSep 16
De la Detección Temprana a la Investigación Clínica: Avances en Diabetes Tipo 1 xitter.cf/i/broadcasts/1RKZzBnDw…
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Breakthrough T1D

De la Detección Temprana a la Investigación Clínica: Avances en Diabetes Tipo 1

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Lina Huerta-Saenz, MD, FAAP retweeted
Breakthrough T1D
@BreakthroughT1DSep 16
De la Detección Temprana a la Investigación Clínica: Avances en Diabetes Tipo 1 xitter.cf/i/broadcasts/1RKZzBnDw…
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Breakthrough T1D

De la Detección Temprana a la Investigación Clínica: Avances en Diabetes Tipo 1

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#T1Dscreening
Helmsley Charitable Trust
@HelmsleyTrustOct 7
Type 1 diabetes is too often only caught once it’s an emergency, when life-threatening diabetic ketoacidosis has developed. Catching T1D in early stages can prevent these emergencies, but to find people at risk we need to implement screening on a much larger scale. Read more about the progress being made in general population screening for T1D in our latest insight post: helmsleytrust.org/news-and-i…
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Lina Huerta-Saenz, MD, FAAP retweeted
Stephen Stone, MD@DiabetesNinjaOct 4
Is the alpha cell a passive bystander in HI? Dr. Diva De León-Crutchlow: islets from HI pancreatectomies show reduced glucagon secretion in KATP and GCK HI. Direct, indirect, or both? And could glucagon replacement be a future therapy? #PedsEndo @ChildrensPhila
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Lina Huerta-Saenz, MD, FAAP retweeted
Lilia Cervantes@Cervantes_Lily1Sep 29
Today @the_asci published an open letter to NIH leadership on proposed changes to K awards, co-signed by 30 professional societies and foundations. Thank you to the ASCI working group and every society and foundation that signed. beta.the-asci.org/news/advoc…

Open letter to the NIH regarding proposed changes to K awards - The American Society for Clinical...

Read more about Open letter to the NIH regarding proposed changes to K awards at The American Society for Clinical Investigation

beta.the-asci.org
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Lina Huerta-Saenz, MD, FAAP retweeted
Helmsley Charitable Trust
@HelmsleyTrustSep 24
More than 5 trillion pieces of plastic litter the ocean, posing a threat to marine life, natural ecosystems, and human health. @TheOceanCleanup, @pmdphawaii, and @coasthuggers are working to clean our oceans, protect wildlife and habitats, and inspire communities to care for coastlines. #ClimateWeekNYC
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Peer-support in #T1D care is very important for #youth and #youngadults with #T1D. Role models can also inspire better #T1Dcare. Join us on 09/26/26 at 10:30AM to meet successful Y/YA with #T1D during our Round Table webinar @BreakthroughT1D #CentralPA
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Pre-register by zoom to attend this free Round Table webinar! @BreakthroughT1D @BT1D_Advocacy #CentralPA
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Lina Huerta-Saenz, MD, FAAP retweeted
NIH
@NIHSep 22
Join the NIH Stadtman Tenure-Track Investigator Program and build your independent research program in a collaborative environment where early-career scientists can think boldly, work across disciplines & tackle biomedical science’s biggest challenges. “What attracted me most to the Stadtman Program was the ability to develop and lead my own independent research program and to do that in a sustained and intentional way, making use of the research environment and trying to make use of the collaborations that are possible here.” - Dr. Tiarnán Keenan, Stadtman Investigator at the National Eye Institute. 🔗 Learn more and apply by 9/30/26: bit.ly/3V1XNcA
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Lina Huerta-Saenz, MD, FAAP retweeted
EASD@EASDnewsJul 23
🗣️🎤𝑺𝑷𝑬𝑨𝑲𝑬𝑹 𝑯𝑰𝑮𝑯𝑳𝑰𝑮𝑯𝑻: Exercise to prevent & treat #diabetes: Join Prof. Jørgen Wojtaszewski (@UCPH_Research) at #EASD2026: 🏃Molecular pathways of insulin resistance & exercise in muscle. 📅Thu, 1 Oct |🕧08:30 - 08:45 CEST|📍Milan Hall 👉easd.org/annual-meeting/easd…
Navy blue promotional graphic for the EASD 2026 Annual Meeting in Milan. A red banner at the top reads "Exercise in Diabetes." Below, white text reads "Uncovering molecular pathways of insulin resistance and exercise benefits in muscle," followed by session details: "1 October 2026 | 08:30 – 08:45 | Milan Hall." A circular headshot in the bottom right shows a smiling older man with gray hair. A red banner beside the photo displays his name, "Jørgen Wojtaszewski." The EASD 2026 Milan logo, styled as a row of cathedral spires, appears in the bottom left, with "easd.org" in the bottom right corner.

ALT Navy blue promotional graphic for the EASD 2026 Annual Meeting in Milan. A red banner at the top reads "Exercise in Diabetes." Below, white text reads "Uncovering molecular pathways of insulin resistance and exercise benefits in muscle," followed by session details: "1 October 2026 | 08:30 – 08:45 | Milan Hall." A circular headshot in the bottom right shows a smiling older man with gray hair. A red banner beside the photo displays his name, "Jørgen Wojtaszewski." The EASD 2026 Milan logo, styled as a row of cathedral spires, appears in the bottom left, with "easd.org" in the bottom right corner.

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Lina Huerta-Saenz, MD, FAAP retweeted
Nature Reviews Endocrinology@NatureRevEndoJul 21
New content online: Diagnosis, staging and management of obesity: a synthesis of contemporary guidelines dlvr.it/TTdz6G
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Promising news for the #T1D community 🙌@HelmsleyTrust #islet cell therapies
Helmsley Charitable Trust
@HelmsleyTrustJul 23
Fourteen months after transplantation and without immunosuppressive drugs, gene-edited donor islet cells are still surviving and producing insulin in a person with type 1 diabetes. The cells remained responsive to meals, producing more insulin following eating. This new follow-up data, published in @NEJM, comes from a study led by Uppsala University Hospital. While this is still early evidence from one participant, and the low-dose study was not designed to eliminate or reduce the need for insulin therapy, this is meaningful progress toward cell therapies that could restore the body’s ability to produce insulin in people with type 1 diabetes. Read more about this Helmsley-supported study: bit.ly/4fEkpGW
Ben Williams is pictured above his quote: “Beta cell transplants are one of many promising therapies in development that could one day be transformative for people living with T1D, and we look forward to continued success of the future studies needed to bring these therapies to the people who are burdened daily by this disease.” Ben Williams is identified as a Type 1 Diabetes Program Officer. The background is a solid blue with a white capital "H" at the bottom.

ALT Ben Williams is pictured above his quote: “Beta cell transplants are one of many promising therapies in development that could one day be transformative for people living with T1D, and we look forward to continued success of the future studies needed to bring these therapies to the people who are burdened daily by this disease.” Ben Williams is identified as a Type 1 Diabetes Program Officer. The background is a solid blue with a white capital "H" at the bottom.

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Lina Huerta-Saenz, MD, FAAP retweeted
Diabetologia@DiabetologiaJnlJul 6
Autoantibody screening in children who are first-degree relatives of people with type 1 diabetes: multicentre prevalence, determinants and post-screening parent–child anxiety #T1D #DiabetesResearch link.springer.com/article/10… 🔓️
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Lina Huerta-Saenz, MD, FAAP retweeted
Stephen Stone, MD@DiabetesNinjaJun 13
“Who will you be when history calls?” Powerful opening from Carol Lange at #ENDO2026. @TheEndoSociety is working hard to advocate for research + clinical care. Find your people. Be your best selves. #ENDO2026 #Endocrinology #Advocacy – at Chicago, IL
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Lina Huerta-Saenz, MD, FAAP retweeted
Diabetologia@DiabetologiaJnlJun 8
#Obesity & #Type2Diabetes can alter the sense of smell and olfactory changes, in turn, influence metabolism. Using evidence from preclinical models🐁🔬, the authors discuss biological mechanisms linking metabolic dysregulation & olfactory impairment link.springer.com/article/10… 🔓
Bulk graphical abstract

ALT Bulk graphical abstract

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Lina Huerta-Saenz, MD, FAAP retweeted
The Lancet Diabetes & Endocrinology@TheLancetEndoJun 6
Dissection of type 2 #diabetes: a #genetic perspective thelancet.com/journals/landi… #ADA2026
The red balloon represents pathogenic variants that cause monogenic diabetes. These variants are typically rare (frequency <0·001) with a strong individual effect (OR >5). The green balloon represents variants that cause oligogenic diabetes. These variants are typically rare or low frequency, with an intermediate to strong effect as a burden (OR around 1·5–7). The yellow balloon represents SNPs associated with type 2 diabetes risk that are typically common (frequency >1%) and have a modest effect on type 2 diabetes risk (OR <1·5). GWAS=genome-wide association study. OR=odds ratio. SNP=single nucleotide polymorphism.

ALT The red balloon represents pathogenic variants that cause monogenic diabetes. These variants are typically rare (frequency <0·001) with a strong individual effect (OR >5). The green balloon represents variants that cause oligogenic diabetes. These variants are typically rare or low frequency, with an intermediate to strong effect as a burden (OR around 1·5–7). The yellow balloon represents SNPs associated with type 2 diabetes risk that are typically common (frequency >1%) and have a modest effect on type 2 diabetes risk (OR <1·5). GWAS=genome-wide association study. OR=odds ratio. SNP=single nucleotide polymorphism.

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Congratulations @DiabetesNinja 👏👏👏
Stephen Stone, MD@DiabetesNinjaJun 7
Come find me at the Late Breaking Poster Session today 12:30-1:30 PM at #ADASciSessions! Board 3007-LB: #RADIANT network data. @ADA_DiabetesPro #ADASciSessions #RADIANT #AtypicalDiabetes #GLUT4 #PrecisionMedicine
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