@LubanLab

Scientist/Professor/Physician/Musician

 NYC, Massachusetts
lubanlab.org
Joined June 2014
  • Tweets10.8K
  • Following4.3K
  • Followers3.7K
1.1KMedia
Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Rockefeller University@RockefellerUniv22 Dec 2023
LINE-1 is associated with disease and aging. The @RoutLab_RU has uncloaked the core of its key protein, pointing the way towards therapeutic targets. #RockefellerScience rockefeller.edu/news/35133-r…
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Rachael Tarlinton@RTarlinton21 Dec 2023
No fruit bats are not magic animals that do not suffer disease consequences of bacterial and viral infections (pathology studies like these are very painstaking to perform) sciencedirect.com/science/ar…
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Melissa AIT SAID@Melissa_AitSaid22 Dec 2023
I couldn't have ended the year with a better gift than to be able to broadly share the main story of my PhD work, recently published in @PNASNews. We found that #PCF11 associates with #WDR82 to silence HIV-1 in latently infected cells. Full article ➡️ doi.org/10.1073/pnas.2313356…
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Yorgo Modis@yorgomodis22 Dec 2023
The HUSH complex guards vertebrate genomes from retroelements. Our new structural/biochemical study on MPP8 reveals the interaction interface with TASOR required for HUSH assembly & suggests links between HUSH & SUMO doi.org/10.1101/2023.12.21.5… @daniilprigozhin @MedCambridge @MRC_LMB
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Yorgo Modis@yorgomodis19 Dec 2023
Looking for a motivated postdoctoral research scientist with cryo-EM and biochemistry experience to join our group to study virus-host interactions and coevolution. We benefit from a great environment @MRC_LMB @MedCambridge @Cambridge_Uni jobs.cam.ac.uk/job/43440/
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Nwosu Lab@NwosuLab19 Dec 2023
Cornell Molecular Biology and Genetics department @CornellMBG has an open call for faculty applicants. Interested candidates please apply. All others please RT. Without a shadow of doubt I have loved it here. academicjobsonline.org/ajo/j…
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Massimo
@Rainmaker197319 Dec 2023
How big is Africa, in reality.
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Cedric🧬➰🧬Feschotte@CedricFeschotte18 Dec 2023
“Transposable elements contribute to nearly 80% of human-specific candidate cis-regulatory elements in cortical cells” 🧠 …🤯 literally! Amazing dataset 🔥 Congrats to all involved! nature.com/articles/s41586-0…
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Suzannah Rihn@Lab_Rihn_th15 Dec 2023
🔔'Tis the season...to apply for a new job?! My group @MedCambridge is recruiting for 2 posts: Postdoc: jobs.cam.ac.uk/job/44181/ Research assistant: jobs.cam.ac.uk/job/44250/ Both roles will seek to improve our understanding of coronavirus cross-species transmission. #preparedness
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Akanksha Thawani, PhD
@AkankshaThawani14 Dec 2023
🔥🔥How does the LINE-1 retrotransposon jump around in the human genome? Super excited to present my postdoctoral work answering this published today @Nature together with twitterless Kathy Collins's lab and @NogalesLab @UCBerkeley nature.com/articles/s41586-0… A 🧵

Template and target-site recognition by human LINE-1 in retrotransposition

Nature - Human LINE-1 ORF2p relies on upstream single-stranded target DNA to position the adjacent duplex in the endonuclease active site for nicking of the longer DNA strand, with a single nick...

nature.com
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Mucosal antibodies in people with infection, not in vaccinated-only individuals. This is a correlate of protection from infection, although not fully validated thelancet.com/journals/ebiom… Great work, based on paired nasal and blood sampling

SARS-CoV-2 convalescence and hybrid immunity elicits mucosal immune responses

In summary, we demonstrate that currently available vaccines elicit strong systemic antibody responses, but SARS-CoV-2 infection generates higher titers of binding and neutralizing mucosal antibodi...

thelancet.com
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Miriam Merad, MD, PhD@MiriamMerad10 Dec 2023
Very excited by our results @Nature showing that IL4R signaling is strongly enriched in myeloid cells that infiltrate mice and lung cancer lesions nature.com/articles/s41586-0…
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Cedric🧬➰🧬Feschotte@CedricFeschotte7 Dec 2023
YES! 💯Thanks Massimo and all who helped organize #RetroPath. What a blast it was! A few intense days of amazing 🦠 science in a stunning spot. I’ve learned a ton and made a bunch of new friends! 🥰
International Workshop on Retroviral Pathogenesis@Retro_Path7 Dec 2023
A big thanks to our fabulous host Massimo Pizzato of @UniTrento for hosting this year's #RetroPath meeting, it was fabulous!
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
International Workshop on Retroviral Pathogenesis@Retro_Path7 Dec 2023
A big thanks to our fabulous host Massimo Pizzato of @UniTrento for hosting this year's #RetroPath meeting, it was fabulous!
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Baldauf Lab@Baldauf_Lab6 Dec 2023
New day, new sessions @Retro_Path @MUSE_Trento
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Cedric🧬➰🧬Feschotte@CedricFeschotte7 Dec 2023
Great talk by Hanna-Mari @Baldauf_Lab comparing antiviral activity of Guanyl-binding proteins of 🧒🐭 🐰! GBP2 & GBP5 are some of my fave restriction factors bc both are activated by retroviral LTRs as @SmithaBadarina2 showed nicely before #RetroPath academic.oup.com/nar/article…

HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression

Abstract. Although endogenous retroviruses (ERVs) are known to harbor cis-regulatory elements, their role in modulating cellular immune responses remains p

academic.oup.com
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Laila El-Haddad@gazamom1 Dec 2023
My family had to move 4 times in and outside of Gaza City after Israel destroyed their house and they ran out of water . They are now being carpet bombed in Rafah-the very area they were told was safe. When will this end?
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Sarafianos Lab
@SarafianosLab1 Dec 2023
Why HIV-2 infection reduces HIV-1 pathogenesis in dual-infected patients? HIV-2 blocks HIV-1 through a) an interferon response; b) an HIV1-specific block conferred by HIV-2 TAR, suppressing HIV-1 transcription by stalling RNApol II at the promoter journals.asm.org/doi/10.1128…

HIV-2 inhibits HIV-1 gene expression via two independent mechanisms during cellular co-infection |...

Twenty-five years after the first report that HIV-2 infection can reduce HIV-1-associated pathogenesis in dual-infected patients, the mechanisms are still not well understood. We explored these...

journals.asm.org
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
The Sato Lab (Kei Sato)@SystemsVirology30 Nov 2023
BREAKING🔔 A new study from G2P-Japan🇯🇵 is out! The preprint will be out so soon, but we first show our results on the efficacy of XBB.1.5 monovalent vaccine - comparison between infection-naïve and XBB-infected individuals. Please retweet/repost🔥 1/
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Jeremy Luban 🧬🦠🔬🩺🎸🎻 retweeted
Spyros Lytras@SpyrosLytras29 Nov 2023
🚨New paper alert! and it's one I'm really excited for! Resurrection of OAS1 from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication now out in @PLOSBiology Here's a 🧵on how we reconstructed an ancient 🦇anti-CoV protein doi.org/10.1371/journal.pbio…
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