Professor Emeritus & Clinician Educator in the Yale Nephrology Section. Former Nephrology TPD, Medical Director for YNHH Inpatient Dialysis & Yale PA Programs.

Joined December 2023
Excellent talk by Dr. Philipp Enghard @P_Enghard from Charité, Berlin, Germany, at ASN Kidney Week 2026 in Denver! 👏🩺 #KidneyWk @ASNKidney 🧪 “Cells in the Urine: What Can They Tell Us?” Part of the exciting session “Advances in Urinary Biomarkers and Their Use in Kidney Disease Management.” A fascinating discussion highlighting how urinary cells and emerging biomarker technologies may provide new insights into kidney disease mechanisms, improve noninvasive diagnostics, and advance precision kidney care. Great to see innovative translational research bridging laboratory discoveries and clinical nephrology! 👏 Congratulations to Dr. Enghard and the session organizers for an engaging and thought-provoking presentation! #KidneyWk #ASN2026 #Nephrology #KidneyResearch #UrinaryBiomarkers #PrecisionMedicine #KidneyHealth
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Congratulations to our program director Dr. Ursula Brewster, honored at #KidneyWk2026 for her year as Chair of the ASN Workforce and Training Committee. Growing the nephrology pipeline is slow work, and she has been at it for a long time. Could not be more proud!
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Renal Rounds this morning: first-year fellow Dr. Sandra Okoro walked through HD vs HF vs HDF, from diffusion and convection to which solutes each clears, and weighed the evidence for hemodiafiltration with a critical eye, in a talk residents and med students could follow too.
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Check out the outstanding series of articles on Women’s Health in Kidney Disease in Kidney360 edited by Menaka Sarav, Ladan Golestaneh, and Ursula C. Brewster.
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A particularly moving moment at the ASON Onconephrology Symposium today. For the first time, the Sajal Sahay Honorary Young Investigator Award was presented, an endowed award created by Dr. Jaya Kala @JayaKala11 an Onconephrologist, and her family in memory of her son.
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Strong peer review advances nephrology research and scientific rigor. This #PRW2026, Kidney360 recognizes its Top 5 reviewers of 2026: Drs. Sandesh Parajuli, Satoshi Minami, Keiichi Sumida, Luis Rafael Álvarez Velázquez, and Abinet Aklilu. #ASNKidney360
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Congratulations to my family @KidneydrChirag and my forebear leading @UTSWNephrology. Could not be prouder for them nor more assured for @ASNKidney’s future! Well done! And special thank you to all who voted!
The 2026 ASN Council Election results are here. Join ASN in congratulating @KidneydrChirag on his election as Executive Councilor and Orson W. Moe, MD, on his election as At-Large Councilor. Their terms begin Friday, January 1, 2027.
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P-CABs may offer a kidney-safe alternative to PPIs for people with CKD. A large study found P-CAB use was associated with a 37% lower risk of kidney replacement therapy initiation compared with PPIs. kidney.pub/KN1809-10 #ASNKidneyNews @MPerazella @NamrataKrishna3
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Mark Perazella retweeted
ASN Kidney News Sept 2026 Are P-CABs Associated With Nephrotoxicity in People With CKD? @NamrataKrishna3 @MPerazella kidneynews.org/view/journals… @asnpublications
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Replying to @MPerazella
Many thanks dear Mark for your kind post, it is much appreciated 🙏🏼🙏🏼😊
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Really elegant work on AIN by @meganlebaker who always makes hard work look easy! @YaleNephrology
Our study of acute interstitial nephritis is out in Nature Communications. We used imaging mass cytometry and single-cell spatial transcriptomics on 106 human kidney biopsies to ask what separates AIN from other causes of AKI at the tissue level. 🧵 nature.com/articles/s41467-0…
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Mark Perazella retweeted
Our study of acute interstitial nephritis is out in Nature Communications. We used imaging mass cytometry and single-cell spatial transcriptomics on 106 human kidney biopsies to ask what separates AIN from other causes of AKI at the tissue level. 🧵 nature.com/articles/s41467-0…
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AIN is under diagnosed and not everyone can get a biopsy. We need noninvasive biomarkers to become accessible for prompt diagnosis and management.
Acute tubular injury versus acute interstitial nephritis in the kidney precision medicine project: doi.org/10.1172/jci.insight.…
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1/ Excellent Renal Rounds this AM: Dr. Akshaya Ramaswami (@drakshayaram) on "Malignant Hypertension and Thrombotic Microangiopathy: Can they complement each other?" A patient presents with severe HTN, AKI, and TMA. Which one caused the other? The answer changes the treatment. 🧵
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Mark Perazella retweeted
How do B cells survive the hypertonic kidney in lupus nephritis? At Medical Grand Rounds, Dr. Irene Chernova took us from the γ subunit of the Na-K-ATPase to extracellular ATP signaling via P2RX4 and P2RX7. Genuinely surprising axis & terrific discussion. Excited for what's next!
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Renal Rounds this morning: 2nd year fellow Dr. Erica Marnet (@Erica_MarnetMD) on “Lupus Nephritis: Treatment Paradigm.” Dysregulated B cells, sustained interferon signaling & how the mechanisms map onto what we actually reach for in clinic. – at New Haven, CT
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Mark Perazella retweeted
Delighted to see my recent JASN perspective featured in ASN’s In the Loop! The PEER Network proposes an ASN-affiliated, centralized pool of external reviewers to address a common bottleneck in the promotion process for academic nephrologists. @ASNKidney @UFNephrology
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Mark Perazella retweeted
Faculty promotion is a defining milestone in academic medicine, yet advancement remains inconsistent and often inequitable across institutions. A new perspective in @JASN_News by Prof. @AmirKazory proposes a national Promotion Evaluation and External Review (PEER) network through @ASNKidney to create a centralized pool of volunteer external reviewers, improving access to independent, qualified promotion letters and making the process more equitable. 🔗 journals.lww.com/jasn/fullte…
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