Nuclear Receptors signaling group led by Mercedes Ricote at @CNB_CSIC. Transcriptional and epigenetic regulation of immune and cardiovascular systems!

Madrid, Spain
Joined October 2020
New! Online now: Weight loss during intermittent fasting, not Mediterranean diet quality alone, is associated with lower inflammation: A randomized controlled trial dlvr.​it/TW0rQh
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MRicoteLab retweeted
La menopausia no es una enfermedad. No es el fin de la feminidad. Y no debería vivirse en silencio. Muchas mujeres enfrentan esta etapa sin apoyo, sin información y con miedo a ser juzgadas —en casa, en el trabajo o incluso en el consultorio. En el #DíaMundialDeLaMenopausia, validemos la experiencia de cada mujer. Vía: @unfpa_lac
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MRicoteLab retweeted
Menopause is a natural stage in women’s lives, marking the end of their reproductive years. On Sunday’s #WorldMenopauseDay, @WHO highlights the importance of understanding this stage and its impact on women's health. who.int/news-room/fact-sheet…
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Groups from @cabimer were also well represented!
✨ Varios grupos del #IIBM participan en el simposio «Advances in Prevention, Early Detection and Treatment of Metabolic Diseases», organizado por la Conexión en Enfermedades Metabólicas (COMETA) - CSIC 🧬 L. Bosca, M. Monsalve, A. Martínez Valverde y S. Martín-Puig, entre otros
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On #InternationalMenopasueDay here is a brief overview of our recent review publication on how #Fats and other #Metabolites in blood change with menopause and how #HormonalTherapies can modulate some of these changes towards a better #cardiovascular profile
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Integrating RNA-seq, metabolomics & proteomics, @GeraldineMaier mapped how exercise rewires metabolism across tissues: • Glycolysis • Fat oxidation • Ketone use • BCAA metabolism @WuTsaiAlliance cell.com/cell/abstract/S0092…
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Gracias a los organizadores. Varios grupos del #CNB #CSIC @CNB_CSIC han participado en el simposio. @MRicoteLab ; Thierry Fischer
✨ Varios grupos del #IIBM participan en el simposio «Advances in Prevention, Early Detection and Treatment of Metabolic Diseases», organizado por la Conexión en Enfermedades Metabólicas (COMETA) - CSIC 🧬 L. Bosca, M. Monsalve, A. Martínez Valverde y S. Martín-Puig, entre otros
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MRicoteLab retweeted
✨ Varios grupos del #IIBM participan en el simposio «Advances in Prevention, Early Detection and Treatment of Metabolic Diseases», organizado por la Conexión en Enfermedades Metabólicas (COMETA) - CSIC 🧬 L. Bosca, M. Monsalve, A. Martínez Valverde y S. Martín-Puig, entre otros
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Held to higher standards. Left off invitations. Pointed to as “diversity” but ignored. These are just some of the hundreds of examples of devaluation women faculty in the United States shared with computational social scientist Katie Spoon. These experiences, more common for women than men, are to blame for the higher rate of attrition for women faculty, Spoon and colleagues report in a new analysis. Learn more: scim.ag/4hOhcH1 @NewsfromScience
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MRicoteLab retweeted
What comes after M1/M2? In our Perspective with @FGinhoux in @ImmunityCP we explore how single-cell technologies and AI can decode the gene programs macrophages use across tissues & microenvironments, and how this modular view could transform immunotherapy cell.com/immunity/abstract/S…
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Such an important paper for the field! Multi-omics atlas of chronic exercise: Cell A comprehensive analysis across scale. Multi-organ responses to exercise training, multimodal integration, and notably, impact of exercise timing! WOW! Well-done!! cell.com/cell/fulltext/S0092…
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MRicoteLab retweeted
We’re delighted to be at the COMETA International Workshop in El Escorial! 🇪🇸 Two days of exciting science, inspiring discussions and new connections around metabolic diseases. Looking forward to sharing our research and learning from this fantastic community! 🔬✨ @IIBmCSICUAM
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MRicoteLab retweeted
We recently introduced DISCO-seq 🤩: scRNA-seq after tissue clearing 🧬 biorxiv.org/content/10.64898… First, image whole organs or bodies in 3D at cellular resolution. Then select regions for unbiased scRNA-seq. From glioblastoma to whole-body SARS-CoV-2 spike mapping 👇🏻 #DISCOseq
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The relationship between obesity and low testosterone. Weigh gain and resulting excess adiposity suppresses testosterone production: 🔹 Increased leptin -> decreased gonadotropin releasing hormone (GnRH), resistance to gonadotropin mediated testosterone production 🔹 Increased estrogen production -> negative feedback onto hypothalamic neurons to produce LH, FSH In those with low testosterone and obesity, the solution isn't testosterone supplementation rather effectively treating the underlying weight gain .
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