
ALT Histological and C5b-9 deposits evaluation in C3 glomerulpathy (a) Representative images of main glomerular patterns: membranoproliferative on the left (arrow indicates glomerular basement membrane duplication) and mesangioproliferative on the right (arrow indicates mesangial cell hypercellularity). Two kidney biopsies did not belong to either of this two patterns: one showed extensive mesangial and parietal deposits, and the other one displayed non significant glomerular lesions on light microscopy (b) C3 glomerulopathy histological index quantification in kidney biopsies: activity and chronicity scores. Violin plot, each individual value is represented by a point. (c) Representative images of glomerular C5b-9 in negative control and C3 glomerulopathy biopsies classified as no/low, intermediate and high. (d) Repartition of kidney biopsies among the 3 glomerular C5b-9 groups.




