CRISPR-Cas applications in plants. Go Hawks.
Des Moines, IA
Joined September 2011
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Excited to share our work on Programmable Transcriptional Activators (PTAs) for plants! We started by screening a library of activation domains in monocots&dicots, culminating in using these PTAs to activate enhancers in protoplasts. onlinelibrary.wiley.com/doi/…
Massive thanks to @Armandomics for all the day to day work in the lab. And of course @Smanski_Lab for the guidance and lessons in perseverance. Congrats to the entire team!
Matt Zinselmeier retweeted
We did not set out to develop new #SynBio tools for plants, but when the existing tools weren't cutting it (or more specifically weren't expressing it), postdoc Armando Casas-Mollano decided we needed improved CRISPRa for plants. [1/2]academic.oup.com/nar/article…
Excited this pre-print is finally up! Big kudos to Ryan for all the hard work. Lots of conversation at Minnesota, to the final experiments at Berkeley. Who would’ve thought messing with Wuschel could be so fun? biorxiv.org/content/10.1101/…
Matt Zinselmeier retweeted
Roots are hard but this is cool. Massive in field root phenotyping->GWAS/selection scans->gene candidates->transgenic validation in a single paper! Seven years of work (2015-2022) and tens of thousands of dug and imaged roots. Respect. (h/t @MZinselmeier) nature.com/articles/s41477-0…
Matt Zinselmeier retweeted
Deep learning based genomic prediction methods can start outperforming conventional GP once you get into the thousands of samples. Tested using data from 1,404 maize lines evaluated in five locations, plus wheat and tomato datasets (h/t @MZinselmeier): pubmed.ncbi.nlm.nih.gov/3636…
Matt Zinselmeier retweeted
Optimized dCas9 Transcription Activators for Plants biorxiv.org/cgi/content/shor… #biorxiv_plants
Matt Zinselmeier retweeted
Our review paper on CRISPR-Cas activators is finally out in @CRISPRjournal. Many thanks to all authors @MZinselmeier, Samuel E. Erickson and @Smanski_Lab for their great work.
CRISPR-Cas Activators for Engineering Gene Expression in Higher Eukaryotes liebertpub.com/doi/abs/10.10…
Matt Zinselmeier retweeted
I’ve had the privilege of meeting Karl and I'm deeply sorry for the loss in his family.
Minnesota has lost 79 of our grandparents, brothers, parents and loved ones to this virus. Each one is heartbreaking. We need to keep working to contain this–it will save lives. #StayHomeMN
Matt Zinselmeier retweeted
WE CAN BEAT THIS, BUT THIS IS SERIOUS AND WE NEED TO TAKE EVERY PRECAUTIONS. youtu.be/0kwI3Pl85Vc via @YouTube
COVID-19: 3995 deaths / 113579 cases worldwide = ~3.5% death rate
Flu: 468500 deaths / 1000000000 cases worldwide = ~0.05% death rate
hopkinsmedicine.org/health/c…
I will be canceling my subscription on Feb 29 and switching to @hulu for the same reason I canceled @Sling and switched to @YouTubeTV months ago. This is so frustrating as a consumer. I now expect Hulu to conveniently drop local sports coverage in 6-12 months time
Matt Zinselmeier retweeted
'What's the harm in giving Gwyneth Paltrow a health show on @Netflix?'
This morning I put two of my children on the school bus. The third is a box of ashes. Health information should come from experts, not celebrities. Stop giving them platforms. 1/5
nbcnews.com/think/opinion/ce…
For all my baseball friends:
“Studies using computed tomography scans revealed that there is a drastic 56.7% difference in the density of the core of the baseballs used during the 2014 and pre-All-Star Game 2015 versus 2017 season in the Major League.”
pubs.acs.org/doi/full/10.102…
Matt Zinselmeier retweeted
Love it when we can harness the knowledge of experts in their field. @MZinselmeier speaking to students today @BlaineHS about GMO’s in agriculture. #ahschools #edchat
Matt Zinselmeier retweeted
Reminder! Our new TV schedule starts on July 14.
@ESPN will broadcast 14 games on ESPNEWS and ESPN2, beginning with #PORvORL on July 14. Every game of the #NWSLPlayoffs and the #NWSLChampionship will be on ESPN2.
Full 📺 schedule, details: nwsl.us/2XpfvTJ
Matt Zinselmeier retweeted
.@BudLight America’s corn farmers are disappointed in you. Our office is right down the road! We would love to discuss with you the many benefits of corn! Thanks @MillerLight and @CoorsLite for supporting our industry.
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