@MachadoIsidrin

Pathology Department. Instituto Valenciano de Oncología and Pathology Department Hospital QuironSalud Valencia

 Valencia, España
Joined December 2016
  • Tweets2.5K
  • Following2.3K
  • Followers1.9K
171Media
Isidro Machado MDPhD retweeted
Michael Arnold, MD, PhD@MArnold_PedPathOct 25
H&E morphology matters! The @COGorg Rhabdomyosarcoma group identified 2 of ~300 cases in ARST1431 that were distinctive, with tingible body macrophages. Additional research testing found a common molecular thread - high amplification of MYCL onlinelibrary.wiley.com/doi/… #PediPath
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Isidro Machado MDPhD retweeted
Greg Charville@Greg_Charville17h
Finally, a histologic biomarker for USP6-associated tumors, led by Margarita Muñoz de Toro @StanfordPath: pubmed.ncbi.nlm.nih.gov/4285… A new technique also highlighted in the excellent recent work by Dinh et al: pubmed.ncbi.nlm.nih.gov/4250… #BSTpath
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See you in the upcoming N.O.D.E session, thanks
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Isidro Machado MDPhD retweeted
Isidro Machado MDPhD@MachadoIsidrinSep 30
See you there , if possible Thanks
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Isidro Machado MDPhD retweeted
Springer Pathology@SpringerPathOct 15
Virchows Archiv reports on four basaloid epithelial tumors with EWSR1 fusions, expanding the understanding of their relationship to syncytial myoepitheliomas and Ewing sarcoma. The study highlights diagnostic challenges in these cases. bit.ly/4imxUgL

Cutaneous basaloid neoplasms with epithelial differentiation and EWSR1-fusions: a series of four...

Virchows Archiv - EWSR1::FLI1 is an established oncogenic driver of Ewing sarcoma, a malignant round cell sarcoma, while EWSR1::PBX3 fusions have been associated with myoepithelioma, in particular...

link.springer.com
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Isidro Machado MDPhD retweeted
Histopathology@Histo_JournalOct 16
Alveolar soft part sarcoma of the female genital tract is very rare. This useful study reports the clinicopathological and molecular features of 26 cases. #gynpath #pathX doi.org/10.1111/his.70302

Alveolar soft part sarcoma of the female genital tract: a clinicopathological and molecular genetic...

We report 26 primary female genital tract ASPS cases, mostly affecting the uterus of young women. Tumours showed diffuse sheets/solid nests of large round cells with abundant eosinophilic-to-clear...

onlinelibrary.wiley.com
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Isidro Machado MDPhD retweeted
Springer Pathology@SpringerPathOct 15
A review of 280 myxoid liposarcoma cases shows that nuclear grading outperforms traditional grading methods in assessing tumor behavior. This study highlights the need for improved prognostic criteria in MLPS management. bit.ly/4s8kWXi
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Isidro Machado MDPhD retweeted
GEIS@GrupoGeisOct 14
Socio de GEIS desde 2010, el Dr. César Serrano inicia su etapa como presidente con la apuesta por una ciencia más moderna, sin perder la esencia del grupo: la colaboración y el espíritu de comunidad. ¡Bienvenido, César! #GEIS #Sarcoma
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Isidro Machado MDPhD retweeted
IMPERAS@proyectoimperasOct 14
La Dra. Cleofé Romagosa y el Dr. Tulio Silva valoran muy positivamente el 3.º Curso IMPERAS de Sarcomas, destacando el alto nivel de los participantes y el compromiso del profesorado. Gracias a todos por compartir conocimiento y seguir impulsando la formación en sarcomas.
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Isidro Machado MDPhD retweeted
Greg Charville@Greg_CharvilleOct 13
Dedifferentiated and undifferentiated melanomas remain underrecognized with significant treatment implications - @aubre_gilbert shows that PD-L1 can provide a useful diagnostic hint (not just a predictive marker!). @StanfordPath @JHUPath
Human Pathology@Human_PathologySep 10
New in #HumPathol: Sarcomatoid malignancies with strong PD-L1 expression often represent dedifferentiated or undifferentiated melanomas. sciencedirect.com/science/ar… #pathology #PathTwitter #PathX #BSTpath
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Isidro Machado MDPhD retweeted
USCAP@TheUSCAPOct 13
Thank you to the Japanese Society of Pathology for organizing a great IAP 2026 meeting in Fukuoka, Japan! Looking forward to hosting the 2028 IAP in Toronto, Canada. @IAPCentral
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Isidro Machado MDPhD retweeted
Human Pathology@Human_PathologySep 10
New in #HumPathol: Sarcomatoid malignancies with strong PD-L1 expression often represent dedifferentiated or undifferentiated melanomas. sciencedirect.com/science/ar… #pathology #PathTwitter #PathX #BSTpath
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Isidro Machado MDPhD retweeted
César Serrano García@DrCeSarcomaOct 3
🚨New #sarcoma paper 📄 Inflammatory rhabdomyoblastic tumor (IRMT) has a very distinctive genomic progression: NF1 as the clonal driver > near-haploidy targeting typically CDKN2A/p16 > WGD progression to rhabdomyosarcoma 👇🏼👇🏼👇🏼
Tulio Silva, MD@TulioMSilvaSOct 3
New work on inflammatory rhabdomyoblastic tumor (IRMT) from a multicenter @proyectoimperas collaboration! NF1 association, near-haploidy, and CDKN2A/p16 loss & WGD in progression to rhabdomyosarcoma. doi.org/10.1016/j.prp.2026.1… #Pathology #Sarcoma #IRMT
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Isidro Machado MDPhD retweeted
IAP Central@IAPCentralSep 30
See the lineup of speakers for the short course and slide seminar programming on dermatopathology at the IAP International Congress, Fukuoka, Japan, October 2026. Register now at iap2026.com/index.html. #pathology #dermpath
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Isidro Machado MDPhD retweeted
Histopathology@Histo_JournalAug 26
An update on novel and emerging cutaneous soft tissue tumours, from two expert pathologists. Interesting reading, even if you do not practise dermatological or soft tissue pathology. #OpenAccess #PathX #dermpath #molpath doi.org/10.1111/his.70262

Novel and emerging cutaneous soft tissue tumours

This review outlines the defining histopathological, immunophenotypic and molecular features of novel and emerging cutaneous soft tissue tumours, including hybrid superficial ALK-rearranged myxoid...

onlinelibrary.wiley.com
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Isidro Machado MDPhD retweeted
Konstantinos LinosMD@KonstantinosLinSep 29
🔬 Excited to join Dermpedia Consults today at 3 PM EST for Cases Extraordinaires — and very happy to be joining Dermpedia as a Consultant going forward! Looking forward to discussing challenging dermpath cases.✨ #Dermpedia #Dermatopathology #Dermpath #Pathology
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Isidro Machado MDPhD retweeted
Jason L. Hornick, M.D., Ph.D.@JLHornickSep 28
Amazing sessions ! @MGBpathology
IAP Central@IAPCentralSep 28
See the lineup of speakers for the short course and slide seminar programming on bone and soft tissue pathology at the IAP International Congress, Fukuoka, Japan, October 2026. Register now at iap2026.com/index.html. #pathology #BSTpath
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Isidro Machado MDPhD retweeted
IMPERAS@proyectoimperasSep 23
La Dra.Romagosa y el Dr. Silva hacen balance del 5.º Workshop IMPERAS y destacan la valoración positiva de la jornada y el trabajo colaborativo. Gracias a patrocinadores, asociaciones de pacientes, entidades financiadoras, ponentes y asistentes ¡Nos vemos el próximo año!
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Isidro Machado MDPhD retweeted
Charlie Herndon@DrCycloPathApr 7
#PathQuiz 🔬🫁 #ThoracicPath A) Synovial Sarcoma B) SMARCA4-deficient undifferentiated tumor C) Epithelioid Hemangioendothelioma D) Primary Pulmonary Myxoid Sarcoma #Pathology Clue in caption 🧐
A 48-year-old male heavy smoker presents with superior vena cava syndrome and a large, invasive mediastinal mass on PET-CT. Discohesive growth of large round to epithelioid cells with prominent nucleoli @IARCWHO

ALT A 48-year-old male heavy smoker presents with superior vena cava syndrome and a large, invasive mediastinal mass on PET-CT. Discohesive growth of large round to epithelioid cells with prominent nucleoli @IARCWHO

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