@MansfeldLab

PTM and cell proliferation lab at the @ICR_London. Tweets are from anyone in the lab :-)

 ICR London
mansfeldlab.com
Joined July 2021
  • Tweets29
  • Following139
  • Followers202
3Media
UK REDOX NETWORK 2025 Meeting at Institute of Cancer Research, London SW7 3RP28 April 2025. Excellent programme coordinated by Olena Rudyk (KCL) and Joerg Mansfeld (ICR). @SFRR_Europe @kingscardio @elsbiomedchem
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UK REDOX NETWORK Meeting Session 2: Helena Cocheme (Imperial College) introduces Joerg Mansfeld (Institute of Cancer Research) (intranet.sfrr-europe.org/doc……; @SFRR_Europe @SFRRAustralasia @SFRBM @CochemeLab @JuliaVorhauser
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Mansfeld Lab retweeted
Anna Poetsch@APoetsch13 Dec 2022
We have several postdoc openings! tu-dresden.de/cmcb/biotec/fo… Our interdisciplinary group works on the #Genomics of #DNAdamage and #Mutagenesis using #ComputationalBiology, #MachineLearning and #AI. (details in following tweets)
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Mansfeld Lab retweeted
Michael Yaffe@mbyaffe25 Nov 2022
An extraordinary paper showing an unexpected redox role for BCAT1 in accurate chromosome segregation. There is clearly something important about how redox changes modulate the cell cycle, especially in mitosis. doi.org/10.1016/j.celrep.202…
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How does polymerisation activate the ADP-ribosyltransferase tankyrase? We are a few steps closer to the answer: rdcu.be/c0hLX. Congratulations to the team, and thank you to our funders, especially @CRUKresearch @wellcometrust @ICR_London @ListerInstitute!
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I am thrilled and honoured to be one of the #ERCStG recipients! So grateful to @ERC_Research, my mentors, colleagues at the @ICR and my family. We will explore the roles of histone acetylation in cancer and will be recruiting soon. erc.europa.eu/news-events/ne…

ERC awards €636m to emerging science talent across Europe

Four hundred eight researchers have won this year’s European Research Council (ERC) Starting Grants. The funding is worth in total €636 million and is part of the Horizon Europe programme.

erc.europa.eu
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Mansfeld Lab retweeted
Pines lab@PinesLab22 Nov 2022
Many congratulations to Alex Radzishueskaya in our Division who has been awarded an ERC Starting Grant!
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Interesting @biorxivpreprint by the group of Ben Cravatt @scrippsresearch with the group of @davidrliu. They use base-editing to assign essentiality to >10,000 cysteines in cancer cell lines. Full post on @joinmastodon @[email protected]. doi.org/10.1101/2022.11.17.5…
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Mansfeld Lab retweeted
Negar Afshar@NegAfshar11 Sep 2022
If you're interested in telomeres and DNA replication, check out this amazing postdoc opportunity in Max Douglas's lab ! linkedin.com/posts/max-dougl…

#hiring | Max Douglas

We are currently looking for a postdoc to join my team in London working on DNA replication and telomeres. If you like biochemistry, biophysics and/or chromosome biology, please take a look! Feel...

linkedin.com
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Mansfeld Lab retweeted
NordenLab@NordenLab11 Aug 2022
The @NerliElisa strikes again! Deterministic and probabilistic fate decisions exist in the same retinal lineage! A tour de force and amazing team effort led and guided by Elisa. She will discuss in more detail, I go on conference and vacation :-). biorxiv.org/content/10.1101/…

Deterministic and probabilistic fate decisions co-exist in a single retinal lineage

Correct nervous system development depends on the timely differentiation of progenitor cells into neurons. While the output of progenitor differentiation is well investigated at the population and...

biorxiv.org
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Mansfeld Lab retweeted
The ICR@ICR_London12 Aug 2022
Professor Chris Bakal's lab (@BakalLabICR) show that #Melanoma #SkinCancer cells harness ARHGEF9 - a gene usually used by growing nerves - to drill through surrounding tissues and escape from their immediate area. Read more: icr.ac.uk/news-archive/skin-…
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Mansfeld Lab retweeted
The ICR@ICR_London27 Jul 2022
📢 NEWS: ICR scientists (@MansfeldLab) have discovered how naturally occurring, unstable molecules, known as free radicals, can directly regulate a key protein for cell division called CDK2, opening up a potential new way to target #Cancer 👇 icr.ac.uk/news-features/news…
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📢 Hot off the press 📢 🧬 Ever wonder why some DNA sequences are difficult to replicate? Using reconstituted replisomes we revealed that structure-forming repeats induce robust replication stalling and uncovered structure-specific recovery mechanisms: nature.com/articles/s41467-0…
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Dr Alexis Barr is a Cancer Research UK Career Development Fellow in the Institute of Clinical Sciences! Find out about Alexis' research on quiescence and interests outside of work on the social media card below and in our profile series booklet: buff.ly/3vQ5fJm
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If you are a PhD student or a postdoc at a Ukrainian university/institute on a topic related to computational or experimental proteomics and you would be interested in a paid internship in my lab @ICR (for ~up to 6 months or more if possible), please email me.
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Great way to start the year! 🧬✂️ Our work on recombinases to correct an inversion in Hemophilia A has just been published in @NatureComms 🥳🎉💃 Congratulations @felix_lansing and all the team! nature.com/articles/s41467-0…

Correction of a Factor VIII genomic inversion with designer-recombinases

Nature Communications - Correction of disease-causing large genomic inversions remains challenging. Here, the authors developed a dual designer-recombinase system (RecF8) that efficiently corrects...

nature.com
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Mansfeld Lab retweeted
The ICR@ICR_London2 Nov 2021
ICR #PhD available in #CancerBiology! Join Dr. Max Douglas' team for the studentship: 'Examining the mechanism of chromatin replication and assembly at telomeres', funded by @The_MRC. Find out more (deadline 14th Nov): icr.ac.uk/studying-and-train… #PhDApplication #PhDProject
Chromosomes and their telomeres (visualised in red). Credit: Thomas Ried, NCI Center for Cancer Research

ALT Chromosomes and their telomeres (visualised in red). Credit: Thomas Ried, NCI Center for Cancer Research

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