Official account for Dr. Lynne Maquat's Lab at UR. Nonsense-mediated mRNA decay. Translational control. Transcriptional regulation. We love everything RNA!

University of Rochester
Joined May 2022
We’re thrilled to partner w/ @ualbany to form a NYS Center of Excellence in RNA research! Co-led by @MaquatLab @wagnerlab_rna, we'll team up to develop RNA-based therapies & train scientists. Huge thx to @HarryBBronson for his support #URochesterReesarch urmc.info/1yr
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Congrats, Elizabeth!
Congratulations goes out to @Dr_EAbshire, a postdoc in the @MaquatLab, who was recently awarded a K99/R00 for her project titled "Regulation of exon junction complex composition and assembly." #URochesterResearch (1/4)
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Katalin Karikó and Drew Weissman – awarded the 2023 #NobelPrize in Physiology or Medicine – discovered that base-modified mRNA can be used to block activation of inflammatory reactions and increase protein production when mRNA is delivered to cells.
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Cheers to RNA biologist Lynne Maquat for officially receiving the Gruber Genetics Prize @Genetics2023 in Australia for her work on nonsense-mediated mRNA decay. Proud to have you represent @UofR on an international stage! #URochesterResearch @MaquatLab urmc.info/15L
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Study in @Nature details a new algorithm to find the most stable, efficient mRNA sequence to use in vaccines. Dave Mathews + @lhuang3 show optimal mRNA sequences lead to ⬆️ protein production, improved immune response @UofR @OregonState #URochesterResearch urmc.info/Wa
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New #URochesterResearch in @ScienceMagazine upends the idea that #CRISPR mounts its defense only by cutting RNA/DNA. It found a Cas protein works w/ a membrane protein 👇to stop infection in bacteria. What?? @mitchellrayoco1 @arica_vanderwal @kellogg_liz   urmc.info/Vy
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That’s a wrap of #2023RNASymposium! An event for the books showcasing a long standing collaboration between these amazing RNA scientists from @TheRNAInstitute & Univ of Rochester Medical Center @BerglundLab @Wagnerlab_RNA @belfort_lab @MaquatLab @begley_lab Dave Mathews
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Using guide RNA, scientists found a way to make some genetic mutations "invisible." The findings in @MolecularCell are helping the search for treatments for #CysticFibrosis & #neurofibromatosis Read: urmc.info/QA @CF_Foundation @GilbertFamilyFd #URochesterResearch
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A big congrats to Lynne Maquat for winning the 2023 Gruber Genetics Prize for her discovery of nonsense-mediated mRNA decay (NMD) in humans! She shares the prize w/ Allan Jacobson from @UMassChan 👏👏 #URochesterResearch #GruberPrize @The_Gruber_Fdtn @Genetics2023 @GeneticsGSA
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Congrats, Dr. Maquat!!!! #RNA #URochesterResearch
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Registration for #CSHAsia meeting on the Now and Future of #RNATherapeutics (csh-asia.org/?content/1309) at Awaji 🇯🇵 in June2023 is now opened! Abstracts submission by April 14! #RNA #mRNA #siRNA #antisense #RNAtranslation #Geneediting #liposome #RNADrugs #mRNAvaccines
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Our next Dean’s Lecture Series event is happening Monday, Dec. 12 and features our very own RNA expert Lynne Maquat, Ph.D. (@MaquatLab). Details here: urmc.info/DS.
It's @AlexanderHewko 's birthday celebration-- and an extra spooky birthday cake for Halloween made by RAP Xavier Rambout in the @MaquatLab! #Halloween
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Read here about the exciting research we are doing on #FragileX with the Pröschel lab, Sakano lab, and @TeliasLab! #URochesterResearch
Q: What do a molecular biologist, neurotologist, geneticist, neuroscientist, & a vision scientist have in common? A: #FragileX research & it's happening @UofR👇 Learn more in our latest newsletter➡️bit.ly/3CSagD2 #URochesterResearch #RareDisease @MaquatLab @TeliasLab
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Congrats, Dave! #URochesterResearch
Dave Matthews and his team of biophysics, biology, chemistry & physics students (a few pictured 👇) earned a @NIGMS MIRA grant (Maximizing Investigators' Research Award) to study RNA structure modeling using physics & sequence comparison. Congrats! #URochesterResearch @UofR  👏
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Congrats, @Wagnerlab_RNA!
Research from @Wagnerlab_RNA 👇& the Tong lab @Columbia reveals the presence of IP6 in the Integrator Cleavage Module. The work in @NatureComms opens up cellular signaling as a potential regulator of Integrator’s transcriptional control #URochesterResearch urmc.info/x9
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BREAKING NEWS: The 2022 #NobelPrize in Physiology or Medicine has been awarded to Svante Pääbo “for his discoveries concerning the genomes of extinct hominins and human evolution.”
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Grad students and postdocs: Check out this conference designed to help women in higher education push through barriers to reach their career goals. Hosted by @UofR's Institutional Office of Equity & Inclusion ➡️bit.ly/3Be1LRQ
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Celebrating 50 yrs of Joan!!! 🥳 Awesome to see so many trainees and friends 😁.
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