
💎 Structural biology 🛠 Protein engineering 🟠 Cytokines Postdoc @SavvidesLab, @InflamResCen & @UGent || @VIBLifeSciences
Ghent, Belgium
Joined September 2022
- Tweets45
- Following265
- Followers84
- Likes117
Iva Marković retweeted
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Iva Marković retweeted
Excited to share our newly published preview in @ImmunityCP covering recent insights into IL-18 activation! There is still much to learn about the pro(domains) and conf(ormations) of IL-1 family cytokines! @julie_andries @SavvidesLab
doi.org/10.1016/j.immuni.202…
Iva Marković retweeted
Read the preprint bit.ly/3QpiUk1 describing a milestone in our de novo antibody design efforts.
Our pipeline can now design high-affinity and stable antibodies in a single round!
Fantastic collaboration with @lab_serrano
@SavvidesLab & Maarten Dewilde @KU_Leuven
Iva Marković retweeted
biorxiv.org/content/10.1101/…
A prodigious effort and interdisciplinary collaborative work by @VIB_Switch_Lab at @VIBLifeSciences @KU_Leuven , @lab_serrano at @CRGenomica, @SavvidesLab at @VIBLifeSciences @InflamResCen @ugent, and Maarten Dewilde Lab @KU_Leuven
Happy to share the #preprint on #denovo #antibody design in a single round yielding stable Abs with high affinity:
lnkd.in/ew5ATYHy
Grateful to be part of great collaboration efforts betwen @VIB_Switch_Lab @KU_Leuven @CRGenomica @InflamResCen @VIBLifeSciences @ugent – at Ghent, Belgium
Iva Marković retweeted
Training the next generations of scientists in experimental structural biology. We are grateful to
@synchroSOLEIL and @Proxima2A
for hosting our Master program in Biochemistry-Biotechnology @ugent for a practical workshop on X-ray crystallography.
Iva Marković retweeted
Delighted to share our work in @NatureSMB on #structures of IL-12/23 cytokine complexes involving the complete extracellular domains of IL-12 family receptors, jointly celebrating 30 years of IL-12 receptor #immunology and @NatureSMB
nature.com/articles/s41594-0…
Iva Marković retweeted
Great start to an inspirational #cytokines2023 at the foot of the Acropolis @CytokineSociety
Iva Marković retweeted
We are heading with a team of seven to Athens, Greece for a very exciting
#cytokines2023
Iva Marković retweeted
Registration & call for #HTCC6 bursaries is open!
For registration go to htcc6.org and take advantage of the bursary and early bird registration! @ccp4_mx
@PDBeurope @ccdc_cambridge @DougInstruments
@IUCr @IUCrJ @ECA_social @MiTeGen @formulatrix @oxcryo @rigaku
Iva Marković retweeted
📢We're recruiting! We’re putting together a research team for an exciting new project to establish Belgium’s first amyloidosis center and we have a PhD student position available. Read more/apply here: bit.ly/44tvW49
Great first days of International school of #crystallography with the focus on #StructuralDrugDesign accompanied by spectacular views from legendary #Erice! Happy to be in #Sicily representing @InflamResCen & @VIBLifeSciences 💎 – at Erice, Sicily
Iva Marković retweeted
PROXIMA 2 hosted students and tutors from the University of Ghent for practicals, tutorials and lectures covering all the steps in X-ray crystallography - crystallisation, harvesting, data collection, structure determination and Savvas Savvides' most famous crystallography quiz!
Very happy to have been part of #SICSpringtimeSchool2023 & share some of the @SavvidesLab's work on blocking #TSLP and learn more about skin immunology! Huge thanks to the organizers for a great event! @skinucph @VIBLifeSciences – at Helsingør, Danmark
It's a wrap! We have rounded off the last day at #SICSpringtimeSchool 2023! It has been an intense, fun and “hyggelig” event! We thank @LEOFondet for making this possible and all of our speakers and participants for joining us from around the world! We hope to see you again soon!
Quick&touristy #Copenhagen warmup for the @skinucph Springtime School 2023 Skin #homeostasis & #inflammation in Hornbæk, Denmark. Looking forward! @LEOFondet – at Copenhagen, Denmark
Iva Marković retweeted
Check out the latest issue of @NatureSMB featuring Tsirigotaki et al. nature.com/articles/s41594-0… on the Leptin-mediated receptor complex as a cover story and additional coverage via a News & Views article
nature.com/articles/s41594-0…
Iva Marković retweeted
"De novo protein design has reached an inflection point, researchers say. AI-powered protein design is becoming very real and very usable, thanks to technological advances in the development of algorithms and the hardware that runs them."
cen.acs.org/physical-chemist…
Iva Marković retweeted
Would you like to design de novo proteins and protein machines? 💻🔬🧬 There is an open PhD position in my group! Please RT and share! Application deadline is 15th of May.

ALT A PhD student position on the topic on de novo protein design is available in the Ljubetič group at the National Institute of Chemistry in Ljubljana, Slovenia Designing dynamic and controllable feet for a de novo protein robot Proteins are nature’s nano-robots, catalysing reactions, recognising molecules, and transporting cargo. Biomimetic nanomachines have the potential to solve current real-world problems, however use is limited by existing folds and inadequate stability of natural proteins. De novo designed proteins are hyper-stable and can achieve properties and shapes not explored by evolution.
Iva Marković retweeted
Now everyone can be a protein designer! 😂
Replying to @_JosephWatson
The code is available both to download from GitHub, and also, thanks to the wonderful @sokrypton, as a Colab Notebook.
github.com/RosettaCommons/RF…
colab.research.google.com/gi…
Iva Marković retweeted
New from David Baker’s lab demonstrating de novo design and characterization of four different classes of small beta barrels.
@UWproteindesign
De novo design of small beta barrel proteins | PNAS bit.ly/3LShf4Y























