Biotech scientist driven to discover new treatments for rare diseases. I’m here for all things mitochondria & Virginia Tech sports.
Blacksburg, VA
Joined December 2017
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New publication looking at mitochondrial structure<->function in heart pathology. 3-D reconstructions compared networked mitochondrial cristae (yellow) to cristae 'orphaned' from network (red). Rewarding collaboration with @ShaikhLab and others!
nature.com/articles/s42003-0…
Dr. David A. Brown retweeted
Hokie Nation, we got our guy 🤝
Coach Franklin’s here to win 🏆
➡️ vthoki.es/25JFHire
🏆 vthoki.es/yAik5
Dr. David A. Brown retweeted
The best we've ever s33n.
The second four-time first teamer in @accwbb history 🫡
4x First Team
3x All-Defensive
Dr. David A. Brown retweeted
GOOD MORNING.
BAD DAY TO BE A WAHOO‼️
GOT A HOME GAME IN CHARLOTTESVILLE TODAY 😤
BE EARLY 🤝
BE LOUD 🗣️
MAKE AN IMPACT 🫡 – at Newark, NJ
Let’s Go! We’ve got a caravan heading to #cassellnorth.
Dr. David A. Brown retweeted
Mitt Romney on what's influencing his vote in November besides policy: character. “Having a president who is so defaulted of character would have an enormous impact on the character of America. And for me that's the primary consideration," he tells me.
Dr. David A. Brown retweeted
The @HokiesWBB team finished the regular season 15-0 in Cassell Coliseum. That’s how you #DefendTheCassell @CassellGuardVT 🏰
Let’s Go Hokies! #baconsheriff and I will be there, loud and early!
Dr. David A. Brown retweeted
You heard it here, ESPN College Gameday in Blacksburg! Be there this Sunday at 11 AM 😎
Game tips off at 2 PM vs North Carolina 🏀
#ThisIsHome | @HokiesWBB
Hard to describe how excited my family and the #baconsheriff are for @HokiesWBB this weekend. Let’s go Hokies!
Dr. David A. Brown retweeted
New from the lab!
Mitochondria from an aged mouse model of Duchenne muscular dystrophy have impaired creatine metabolism and oxidized mitochondrial CK (thiol labeling).
Targeting mitochondria with the peptide SBT-20 rescued mitochondrial creatine metabolism + lowered H2O2. 1/3
Disrupted cardiac bioenergetics linked to oxidized mitochondrial creatine kinase are rescued by the mitochondrial-targeting peptide ... biorxiv.org/cgi/content/shor… #biorxiv_physio
EPIC win by the @HokiesWBB today. Bonus with my son captured in the moment! He laid out his outfit like the first day of school this morning. Go Hokies! #Hokies
Dr. David A. Brown retweeted
All Senate Dems Republicans that
see reason
🤝
Shutting down the government is crazy, actually
Dr. David A. Brown retweeted
Fantastic day @MRCMouseNetwork Industry event to launch the @The_MRC Business Engagement Fund. Huge opportunities exist for @MRCMouseNetwork to catalyse clinical translation of experimental medicines through commercial partnerships.
Dr. David A. Brown retweeted
We identified a compound that binds the IF1 groove of ATP Synthase and inhibits ATP hydrolysis. In cells with impaired respiratory function, inhibition of ATP hydrolysis by CV can increase cellular ATP content even without restoring respiratory function
embopress.org/doi/full/10.15…