My yeast and human genomics lab investigates lipid storage diseases as well as traditional medicines with Māori & Pacific Island organisations and communities.
Victoria University of Wellington
Joined May 2018
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Congratulations to Storm for defending her PhD thesis! Ngā mihi nui (thank you) @manucaddie for starting this project---inspiring research with Hikurangi Bioactives. From @WellingtonUni @VicUniWgtn to @Columbia --best wishes Storm on your postdoc with @RebeccaHaeusler.
#Indigenous knowledge + #Yeast #genomics + Bioactivity-guided #metabolomics = Molecular insight into #ethnobotany
Sweet collaboration of healers & scientists @Seeseei1 @djjgresham @Pdorrestein1 @GNPS_UCSD @darachm among others.
pnas.org/content/118/45/e210…
Absolutely loved chasing this fungus around the Americas for my PhD. Parasite to some, delicacy to others. Collected from teosinte in Mexico, that was cool, but maize domestication wiped out the pre-domestication fungal population history.
royalsocietypublishing.org/d…
Congrats HY, Nieng and others on your very nice paper. And thank you for alluding to our @jlipidres paper showing the connections between NPC1 and COVID-19 jlr.org/content/early/2020/0…
Our #COVID19 #SARSCoV2 paper is published @jlipidres. Antiviral activity & lipid dysregulation in rare disease identifies new treatments.
bit.ly/2AeNdpf
@Columbia @VicUniWgtn @SzabiMarka @nnpdf @NiemannPickUK @inpda_org @RareDisordersNZ @NiemannPickOz @ChiefSciAdvisor
Yes so much to learn from rare diseases particularly the lysosomal storage diseases. eg very good insight from Niemann-Pick type C disease. Image here from our preprint
osf.io/92f3s
My kid had a #StrangerThings lockdown birthday. Happy birthday to all the kids around the world who had birthdays in #COVID19 isolation.
First of many zoom lab meetings. We missed a few people due to their jobs being essential. Not sure what chatting was going on during the meeting (zoom in to the orange).
Great point Ethan. This commonality likely means a lot for mechanism. We just published a preprint that expands on this---too much to learn from rare diseases like NPC disease. osf.io/92f3s/
When you have time to cook a present from a student that finished her MSc thesis in my lab in 2017. Her thesis results were published @jbiolchem & downloaded 3200 times. That’s about the number of tasty bites of this leg of lamb. Thank you Natalie.
jbc.org/content/292/11/4395.…
Insight into #COVID19 #SARSCoV2 #pandemic from a rare disease #cholesterol #lysosome #chloroquine
@Columbia @VicUniWgtn @taminraj1 @SzabiMarka
Preprint osf.io/92f3s
@nnpdf @NiemannPickUK @inpdr_tweets @inpda_org @RareDisordersNZ @NiemannPickOz @OSFramework
Lab is officially closed for the 4 week lockdown of new zealand. Time to take down COVID-19. No more nice views of the city from the lab. Time to work from home and do sunset walks close to home with family.
Good call @jacindaardern moving to national lockdown. Ditto that said my class at @VicUniWgtn. Stay well everyone and please follow the lockdown rules.
Thank you everybody. My wish is to win the lotto tomorrow and fund high risk research in our lab. @cintyadelrio @tia_haira @taminraj1
Gene(sis): Contemporary Art Explores Human Genomics could be a contender. It traveled around in 2003-2004 (UC-Berkeley, Univ of Washington, Univ of Minnesota). Really good getting people to ask questions that are still being asked 15 years later. Sign me up for your course.
#plantbiology job in New Zealand! My department is hiring (teaching & research, permanent aka hired with tenure). Diversity of people&topics encouraged eg #mycorrhizal #medicinal #syntheticbiology #plantpathology #genomic #genetic. bit.ly/3513JDW go.nature.com/2YtixbK
Boys 9 year old sunfish team @IslandBayUnited would RT if they could. They scream you are best all whites defender ever. Here's a pic when we saw you play this year.
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Oh to be @cshlmeetings #cshhist19 #yeastresearch to share our new #geneticinteractionnetwork #systemsbiology #geneticbackground paper. Much more to yeast than S288C.
@YeastCourseCSHL
@UdPrfrNAgo
@DunhamLab
@abarysh
@djjgresham
@yeastgenome
@gsherloc
nature.com/articles/s41540-0…
New #statin #epistasis #geneticinteractionnetwork #networkscience #networkmedicine #systemsbiology #geneticbackground #genomics #drugdiscovery #yeast paper from our lab! 👍👍 students. @ENiktab @MWC_CoRE @VicUniWgtn @Nature_NPJ @nresearchnews nature.com/articles/s41540-0…
