Joined March 2019
A new study shows that a small cluster of neurons called the locus coeruleus has a specialized pathway to the brainstem that controls sound-evoked awakening with the release of norepinephrine. @LabNir @NMatosevich scim.ag/4n7G8t9
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My PhD paper is finally out! 🎉 We show how specific LC pathways shape sound-evoked awakening, revealing LC heterogeneity in action. So grateful to all the amazing people who made this possible 🙌
🚨 New paper alert! 🚨(1/6) Excited to share our work, out now in Science Advances We show that a rapid norepinephrine surge along a brainstem pathway (LC→PRN) is a key driver of sound-evoked awakenings science.org/doi/10.1126/scia…
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Tired of spending months teaching every new student how to clean and analyze sleep EEG? 🧠💤 We were too. @LabNir That's why we built SleepEEGpy- a simple open-source pipeline to make sleep EEG research faster, easier, and standardized! 👇 doi.org/10.1016/j.compbiomed…
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This looks amazing! Congrats! Will definitely read in depth and discuss in @LabNir
👉👉New paper alert from @LabLuthi ! Newly promoted Dr. Cherrad, with @GFoustoukos, @FernandezLmj and others combines stimulation of sensory neurons from the #vagus nerve with #sleep, #heartrate, temperature and #locuscoeruleus recordings @unil #FBM #Neuro
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Pupil size reveals arousal level fluctuations in human sleep nature.com/articles/s41467-0….
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Noa Matosevich retweeted
Here's our latest issue: cell.com/neuron/current The cover is for a Perspective piece by Lüthi & Nedergaard who discuss microarousals, and propose an inverted U-shaped relationship to reconcile their essential and disruptive roles: cell.com/neuron/fulltext/S08… Cover by Nadia Alzoubi
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Made it to the cover 🥹
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Finally, selective synaptic silencing using an optoGPCR PdCO demonstrated that silencing LC synapses in the PRN is sufficient in elevating sigma power in EEG during NREM sleep.
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In conclusion, we found LC heterogeneity in the context of sleep and arousal. More specifically, our work reveals a specific pathway critical to sound evoked awakenings.
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Let’s share some data! @LabNir 🧵 We’re thrilled to announce our new paper in @ScientificData featuring an open iEEG dataset from two medical centers and an ML model for detecting interictal epileptiform discharges during sleep 🧠⚡ 👉 nature.com/articles/s41597-0…
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📢My PhD work on the "Deleterious effects of social isolation on neuroendocrine-immune status and cancer progression in rats" is finally out in @BrainBehavImm! 🔗sciencedirect.com/science/ar… @of_sagol @PNIRS
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Check out the latest from our lab, an in-depth look at the neural and peripheral response to social isolation in rats. Led by the exceptional @estherina_t who is a force of nature! 💫
📢My PhD work on the "Deleterious effects of social isolation on neuroendocrine-immune status and cancer progression in rats" is finally out in @BrainBehavImm! 🔗sciencedirect.com/science/ar… @of_sagol @PNIRS
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