@NeuroStemCell

Everything about #NeuroStemCells #StemCells #BrainOrganoids Research. Curated by @DrRaulDM

Joined March 2016
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Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis ift.tt/DAd8QEL
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Induced Pluripotent Stem Cells and Their Applications in Amyotrophic Lateral Sclerosis ift.tt/iNojg3F
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High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca2+ Fluorescence Measurements in Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neuronal 2D and 3D Cultures ift.tt/u5RhO8t
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Use of in vitro derived human neuronal models to study host-parasite interactions of Toxoplasma gondii in neurons and neuropathogenesis of chronic toxoplasmosis ift.tt/p7LV2Ee

Use of in vitro derived human neuronal models to study host-parasite interactions of Toxoplasma...

Toxoplasma gondii infects approximately one-third of the world's population resulting in a chronic infection with the parasite located in cysts in neurons in the brain. In most immunocompetent hosts...

pubmed.ncbi.nlm.nih.gov
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Human neurons lacking amyloid precursor protein exhibit cholesterol-associated developmental and presynaptic deficits ift.tt/SCjq2p0
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Prediction of in vivo prenatal chlorpyrifos exposure leading to developmental neurotoxicity in humans based on in vitro toxicity data by quantitative in vitro-in vivo extrapolation ift.tt/s70HuEm
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Derivation of Sendai-Virus-Reprogrammed Human iPSCs-Neuronal Precursors: In Vitro and In Vivo Post-grafting Safety Characterization ift.tt/eK0iFvH

Derivation of Sendai-Virus-Reprogrammed Human iPSCs-Neuronal Precursors: In Vitro and In Vivo...

The critical requirements in developing clinical-grade human-induced pluripotent stem cells-derived neural precursors (hiPSCs-NPCs) are defined by expandability, genetic stability, predictable in...

pubmed.ncbi.nlm.nih.gov
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Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets ift.tt/J01D7o6
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Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders ift.tt/2jLqZDH

Protein interaction studies in human induced neurons indicate convergent biology underlying autism...

Autism spectrum disorders (ASDs) have been linked to genes with enriched expression in the brain, but it is unclear how these genes converge into cell-type-specific networks. We built a protein-pro...

pubmed.ncbi.nlm.nih.gov
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The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism ift.tt/uq8x3V0
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Optimized synthesis and pharmacological evaluation of HCN channel inhibitor EC18 ift.tt/5jtA7nl
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Functional neurological restoration of amputated peripheral nerve using biohybrid regenerative bioelectronics ift.tt/zev9Vfu

Functional neurological restoration of amputated peripheral nerve using biohybrid regenerative...

The development of neural interfaces with superior biocompatibility and improved tissue integration is vital for treating and restoring neurological functions in the nervous system. A critical factor...

pubmed.ncbi.nlm.nih.gov
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Directed differentiation of human induced pluripotent stem cells into midbrain ift.tt/YERTk2a

[Directed differentiation of human induced pluripotent stem cells into midbrain] - PubMed

HiPSCs can be effectively induced to differentiate into DAPs capable of differentiating into functional neurons both in vivo and in vitro. In rat models of PD, the transplanted hiPSCs-DAPs can...

pubmed.ncbi.nlm.nih.gov
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Human Cytomegalovirus Induces Significant Structural and Functional Changes in Terminally Differentiated Human Cortical Neurons ift.tt/47MQijH
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Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival ift.tt/KGvQMJA
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Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a pain model for analgesic drug testing ift.tt/5izaOTS

Development of a functional human induced pluripotent stem cell-derived nociceptor MEA system as a...

The control of severe or chronic pain has relied heavily on opioids and opioid abuse and addiction have recently become a major global health crisis. Therefore, it is imperative to develop new pain...

pubmed.ncbi.nlm.nih.gov
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iPSC-sEVs alleviate microglia senescence to protect against ischemic stroke in aged mice ift.tt/6PLfXh7
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Three-dimensional co-culture platform of human induced pluripotent stem cell-derived oligodendrocyte lineage cells and neurons for studying myelination ift.tt/71tAWYj

Three-dimensional co-culture platform of human induced pluripotent stem cell-derived oligodendroc...

Developing an in vitro platform to study neuron-oligodendrocyte interaction, particularly myelination, is essential to understand aberrant myelination in neuropsychiatric and neurodegenerative...

pubmed.ncbi.nlm.nih.gov
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Downregulation of Hsp90 and the antimicrobial peptide Mtk suppresses poly(GR)-induced neurotoxicity in C9ORF72-ALS/FTD ift.tt/nbWxhej
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Kv7-specific activators hyperpolarize resting membrane potential and modulate human iPSC-derived sensory neuron excitability ift.tt/m8S5hsU
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