Ngo Lab at UQ. Investigating mechanisms of neurodegeneration and ageing. Researching across the clinic and the lab.
Brisbane, Queensland
Joined July 2018
- Tweets344
- Following261
- Followers349
- Likes363
Ngo Lab Group retweeted
Delivering and expressing a gene in cells is usually a messy (heterogeneous) process. The messiness interferes with research and applications such as gene therapy.
In two new papers, we introduce a toolbox of synthetic miRNA-based control circuits that enable more precise, gene dosage-invariant gene expression, and show how they improve a mouse model of Rett syndrome gene therapy:
biorxiv.org/content/10.1101/… ,led by @RongrongDu123 and @MichaelJAFlynn
biorxiv.org/content/10.1101/… , led by @MichaelJAFlynn and Acacia Mayfield, in collaboration with Viviana Gradinaru.
Ngo Lab Group retweeted
I'm behind @broadinstitute's benchmarking efforts led by Sami and team. While our preliminary work took a different approach and strategy, we ended up demonstrating the same findings.
Stay tuned. More on this soon.
biorxiv.org/content/10.1101/…
biorxiv.org/content/10.1101/…
Ngo Lab Group retweeted
Are you a Civil, Electrical, Mechatronic or Telecommunications Engineering Graduate? Apply now to launch your career at Powerlink Queensland with the 2025 Graduate Program.
At Powerlink we get to work on some exciting projects. With amazing career development opportunities and a broad range of inclusive benefits, there are so many graduate possibilities at Powerlink.
But don’t just take our word for it… Meet Eugene and find out more what he thinks the coolest things are about being part of the Powerlink graduate program.
Applications for our 2025 Graduate Program MUST CLOSE Sunday, 24th of March 2024 at 11:59pm.
Find out more and apply now at bit.ly/490h8wS
At Powerlink, graduate possibilities start with us.
#graduateprogram #graduates #everypossibility #careers #electricalengineering #operationaltechnology #engineering
#civilengineering #mechatronicengineering #telecommunications #womeninengineering #transmissioncareers #careersintransmission #careersinpower #careers #workwithus #applynow
Ngo Lab Group retweeted
New review by my colleagues 🥳
The endolysosomal pathway and ALS/FTD: Trends in Neurosciences cell.com/trends/neuroscience…
Ngo Lab Group retweeted
#FDAapproves treatment of amyotrophic lateral sclerosis (ALS) associated with a mutation in the SOD1 gene: fda.gov/drugs/news-events-hu…
ALT Graphic of a man in a wheelchair wearing jeans and an orange jacket. He is outside in a parking lot with a tree and a building behind him. Blue FDA logo in the bottom right corner
Ngo Lab Group retweeted
Well worth a listen if @WrayNaomi is presenting
Don't miss the #FREE @NatureGenet webcast on polygenic scores with @WrayNaomi and @minouye271! Register here: go.nature.com/3GzwoFQ
Ngo Lab Group retweeted
So proud to have my first first-author paper, Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T, published in @JOSS_TheOJ with @Fred_Steyn @NgoShyuan Rob Henderson, Christine Guo @sbollmann_MRI Jurgen Fripp @MarkusBarth2 and @thomcat992 ✨🎉🧠
Just published in JOSS: 'Open-Source Hypothalamic-ForniX (OSHy-X) Atlases and Segmentation Tool for 3T and 7T' doi.org/10.21105/joss.04368
Ngo Lab Group retweeted
Not long to go now before the start of day 3 of the #ANZMNDsym. A great lineup of speakers. Thank you @MND_RIA and @FightMND for putting together a great program.
Ngo Lab Group retweeted
What a fantastic first session and panel discussion for this morning on #TDP43 #ANZMNDSym @adamkeithwalker @EmmaLScotter @Rebecca_SanGlia, @molly_swanson Marco Morsch, Aaron Russell, and Catherine Blizzard
Ngo Lab Group retweeted
Fantastic morning listening to personal experiences and researcher updates in the first session - MND Care and Research #ANZMNDSym
Ngo Lab Group retweeted
We're taking time this #InternationalWomensDay to showcase some of our amazing women researchers. Meet Jeryn Chang (@JerynChang) who is working on Motor Neuron Disease #MND
#IWD #InternationalWomensDay2022
Ngo Lab Group retweeted
Out @Nature!
TDP-43 path induces crucial synaptic UNC13A mis-splicing and loss. ALS risk SNPs exacerbate this, worsening disease progression.
We uncover the elusive UNC13A risk SNP mechanism, suggesting patients may do better if we correct UNC13A splicing.
nature.com/articles/s41586-0…
Ngo Lab Group retweeted
Culmination of our studies over the past decade has led to a mechanistic and preclinical study out in @jclinicalinvest. We developed a non-muscle targeted #LGMD 2B #genetherapy that safely improved muscle fibre repair and muscle health jci.org/articles/view/141295…
Ngo Lab Group retweeted
Hi amazing graduate students! Come join our lab as a #postdoctoral fellow on funded projects to engage in the exciting cell biology of #neurodegeneration and links to #AxonalTransport, endolysosomal biology #liquidphase separation, amongst others! #prion @Alzheimers Please RT :)
Ngo Lab Group retweeted
Apply for the 2022 Scott Sullivan MND Research Fellowship.
Enhance collaborations between clinical and basic MND Research
Only open to those currently or planning to work in Qld.
Must be <12years post higher degree.
Closes at 6:00pm AEST Thurs 23rd Sept.
ow.ly/eu2350G1ffG
Ngo Lab Group retweeted
New book published today. My sis has built on her academic book to make a book for carers. Such an important topic for quality of life. "Why dementia makes communication difficult" @Cardiffuni @DementiaAus
bookdepository.com/Why-Demen…
Ngo Lab Group retweeted
Could funding help your #research move from the idea's board to clinical practice?
The 2021 Clinical Innovation Grant Round could support your new or current research.
Find out more - wesleyresearch.org.au/grant-…
#GivingHope & #ChangingLives #helptoday #wesleyresearch
Ngo Lab Group retweeted
Using human patient cells and a knockin mouse model, our recent study has demonstrated that Rab7 mutation in CMT2B induces mitochondrial fragmentation through Drp1. Mitochondria dysfunction in Charcot Marie Tooth 2B Peripheral Sensory Neuropathy biorxiv.org/content/10.1101/…
Ngo Lab Group retweeted
Cognitive deficits in people who have recovered from COVID-19 thelancet.com/journals/eclin…
Ngo Lab Group retweeted
We are recruiting a new neuroscience postdoc! Our lab at the Florey Institute of Neuroscience and Mental Health (@TheFlorey) is on the dynamic University of Melbourne (@unimelb) campus in Parkville. For other details, and to apply, please see: floreyinstitute.applynow.net…. Please RT!