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Huge congratulations to Andy on the publication of his PhD work!
This was a massive team effort, thanks to the lab for helping out & collaborators: @DrCDowling @IngmarSchoen @emmamarykerr @marie_mcilroy
Read it here: rdcu.be/eyagL 🙏 @Researchirel For Funding.
A new RCSI study in @NatureComms reveals how blocking HDAC6 alters metabolism in cancer cells.
It also shows a new role for HDAC6 in regulating cells' energy pathways, making it a potential target for tumour metabolism.
Read the paper ➡️ doi.org/10.1038/s41467-025-6…
#RCSIdiscover

ALT Microscopy image of mitochondria, stained to highlight their elongated, branched structures in vivid orange and pink tones, with bright cyan areas indicating stained nuclei or other subcellular components. The background is black for contrast. Overlay includes the RCSI University of Medicine and Health Sciences crest and the RCSI Discover branding.
Triona Ní Chonghaile retweeted
75 YEARS AND THE WAIT IS OVER!!!!!
MAYO ARE FINALLY ALL-IRELAND FOOTBALL CHAMPIONS!!!!!!
📺 Watch on RTÉ2 and RTÉ Player
📻 Listen on RTÉ Radio 1
#SundayGame
Triona Ní Chonghaile retweeted
Advanced fellowship in leukemia @DanaFarber for 2027-2028, application is open. Led by @LuskinMarlise:
jobcenter.hematology.org/job…
Congratulations to @DanielAlencar_R on the publication of his paper nature.com/articles/s41467-0…. To go from a broad phenotypic screen to identifying D567 in human CD2 domain for interaction of BAS-2 with HDAC6 has taken years and numerous collaborations.
In particular, I'd like to thank David Christianson from the University of Pennsylvania for the Crystal Structures, @MMResearchIRE - activity of the SAR compounds, @wangyu39711484 - BLI measurements and @CianFDArcy -proteomics and @aisling1751 - mutagenesis. Thanks to all🙏🙏
Triona Ní Chonghaile retweeted
First genomic-based prognostic test for multiple myeloma launched in Ireland imt.ie/news/first-genomic-ba…
Triona Ní Chonghaile retweeted
Now online in @CD_AACR: Genotype-to-Phenotype Mapping of Somatic Clonal Mosaicism via Single-Cell Co-Capture of DNA Mutations and mRNA Transcripts by @dennisjyuan, @landau_lab, and colleagues doi.org/10.1158/2159-8290.CD… @nygenome @WeillCornell
Now online: Genotype-to-phenotype mapping of somatic clonal mosaicism via single-cell co-capture of DNA mutations and mRNA transcripts doi.org/10.1158/2159-8290.CD…
Triona Ní Chonghaile retweeted
Glad to share our latest paper @jclinicalinvest on targeting KIF20A on sensitizing TNBC to chemotherapy @UTSW_Pathology @utswcancer Targeting kinesin family member 20A sensitizes stem-like triple-negative breast cancer cells to standard chemotherapy jci.org/articles/view/182394
Triona Ní Chonghaile retweeted
Interested in tumour metabolism? 🧪
The Keystone Symposia "Tumour Metabolism: New Frontiers in Diet, Microbiome, and Beyond” is taking place next June. Exciting science and discussions ahead — join us there!
#KeystoneSymposia
#TumourMetabolism
#DietandCancer
Triona Ní Chonghaile retweeted
In aitheantas an tacaíocht faighte ó chomhluadar RCSI maidir lenár aidhm “oideas, cothú agus aimsiú ar son na sláinte”, cuireann sé áthas orainn léiriú inár dTuaraisc Bhliantúil an méid atá tárlaithe in RCSI le linn 2024-2025.
Féach anseo rcsi.com/annualreport
Triona Ní Chonghaile retweeted
A major step forward for personalised cancer care in Ireland.
@BreakthroCancer is a proud partner of @PrecisionOncIre as Phase 2 (€28M) launches today - doubling investment and ambition to make research part of everyday care.
breakthroughcancerresearch.i…
#MakeMoreSurvivors
Triona Ní Chonghaile retweeted
‘Patients at the table…all the way through’ inspirational @SiobhanGaynor speaking at @PrecisionOncIre P2 launch…well done Walter, Donal & co @Researchirel @donalb5 @sysbioire @ucddublin @AlCRIproject @IrishCancerSoc
Triona Ní Chonghaile retweeted
The writer, broadcaster and documentary maker Manchán Magan has died at the age of 55, his family has confirmed
rte.ie/news/2025/1003/153656…
Triona Ní Chonghaile retweeted
Excited to share a new paper and online resource from our lab published today. We developed a mass spectrometry approach that leverages genetic diversity to systematically nominate functional relationships between metabolites and proteins. nature.com/articles/s41586-0…
Triona Ní Chonghaile retweeted
Thanks so much to @LPTrustUK for supporting our new research project! This will be led by Claire Fitzgerald @ClaireFitzG18 @sysbioire @UCDMedicine with collaborators @NiTriona and Cormac Taylor @UCD_Conway . More details in the links below!
📣 We’ve supported @LPTrustUK in funding four new #BloodCancer research projects!
🔬 CAR-T therapy optimisation - Dr Barnett
🧬 SET gene research - @MariaTeresaEs
🔥 Targeting metabolism - @jbond2019
🔍 Treatment resistance - Prof Turner
Find out more at bit.ly/4lBeQKn
Triona Ní Chonghaile retweeted
#ESHALL2025 Our Team is ready to welcome you in Malahide, Ireland for the 4th Translational Research Conference on ALL!
Registration opens tomorrow at 7:30 am!
More information ➡bit.ly/4cy9jAS
Chairs: Kathrin Bernt, @CoolsJn @DombretHerve @ullawk
#ESHCONFERENCES #LEUsm
Triona Ní Chonghaile retweeted
Did you ever wonder why our marrow is located inside of our *bones*, #MedTwitter? There’s no a priori anatomical reason it should be sited there. Blood cells could form in our spleens & livers, as they do during our fetal lives; or elsewhere, as in some animals. Let’s discuss! /1































