Cancer Biologist that likes killing cells - cancer cells. A Senior Lecturer at the Royal College of Surgeons in Ireland. Comments are my own.

Ireland
Joined March 2013
Huge congratulations to Andy on the publication of his PhD work! This was a massive team effort, thanks to the lab for helping out & collaborators: @DrCDowling @IngmarSchoen @emmamarykerr @marie_mcilroy Read it here: rdcu.be/eyagL 🙏 @Researchirel For Funding.
A new RCSI study in @NatureComms reveals how blocking HDAC6 alters metabolism in cancer cells. It also shows a new role for HDAC6 in regulating cells' energy pathways, making it a potential target for tumour metabolism. Read the paper ➡️ doi.org/10.1038/s41467-025-6… #RCSIdiscover
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75 YEARS AND THE WAIT IS OVER!!!!! MAYO ARE FINALLY ALL-IRELAND FOOTBALL CHAMPIONS!!!!!! 📺 Watch on RTÉ2 and RTÉ Player 📻 Listen on RTÉ Radio 1 #SundayGame
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Oooh the green and red of Mayo..
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Advanced fellowship in leukemia @DanaFarber for 2027-2028, application is open. Led by @LuskinMarlise: jobcenter.hematology.org/job…
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In particular, I'd like to thank David Christianson from the University of Pennsylvania for the Crystal Structures, @MMResearchIRE - activity of the SAR compounds, @wangyu39711484 - BLI measurements and @CianFDArcy -proteomics and @aisling1751 - mutagenesis. Thanks to all🙏🙏
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Now online in @CD_AACR: Genotype-to-Phenotype Mapping of Somatic Clonal Mosaicism via Single-Cell Co-Capture of DNA Mutations and mRNA Transcripts by @dennisjyuan, @landau_lab, and colleagues doi.org/10.1158/2159-8290.CD… @nygenome @WeillCornell
Now online: Genotype-to-phenotype mapping of somatic clonal mosaicism via single-cell co-capture of DNA mutations and mRNA transcripts doi.org/10.1158/2159-8290.CD…
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Glad to share our latest paper @jclinicalinvest on targeting KIF20A on sensitizing TNBC to chemotherapy @UTSW_Pathology @utswcancer Targeting kinesin family member 20A sensitizes stem-like triple-negative breast cancer cells to standard chemotherapy jci.org/articles/view/182394
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Interested in tumour metabolism? 🧪 The Keystone Symposia "Tumour Metabolism: New Frontiers in Diet, Microbiome, and Beyond” is taking place next June. Exciting science and discussions ahead — join us there! #KeystoneSymposia #TumourMetabolism #DietandCancer
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Unprecedented. #ASH25 Tec-Dara in relapsed myeloma. @mvmateos
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In aitheantas an tacaíocht faighte ó chomhluadar RCSI maidir lenár aidhm “oideas, cothú agus aimsiú ar son na sláinte”, cuireann sé áthas orainn léiriú inár dTuaraisc Bhliantúil an méid atá tárlaithe in RCSI le linn 2024-2025. Féach anseo rcsi.com/annualreport
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A major step forward for personalised cancer care in Ireland. @BreakthroCancer is a proud partner of @PrecisionOncIre as Phase 2 (€28M) launches today - doubling investment and ambition to make research part of everyday care. breakthroughcancerresearch.i… #MakeMoreSurvivors
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‘Patients at the table…all the way through’ inspirational ⁦@SiobhanGaynor⁩ speaking at ⁦@PrecisionOncIre⁩ P2 launch…⁦well done Walter, Donal & co @Researchirel⁩ ⁦@donalb5⁩ ⁦@sysbioire⁩ ⁦@ucddublin⁩ ⁦@AlCRIproject⁩ ⁦@IrishCancerSoc⁩
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Excited to share a new paper and online resource from our lab published today. We developed a mass spectrometry approach that leverages genetic diversity to systematically nominate functional relationships between metabolites and proteins. nature.com/articles/s41586-0…
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Thanks so much to @LPTrustUK for supporting our new research project! This will be led by Claire Fitzgerald @ClaireFitzG18 @sysbioire @UCDMedicine with collaborators @NiTriona and Cormac Taylor @UCD_Conway . More details in the links below!
📣 We’ve supported @LPTrustUK in funding four new #BloodCancer research projects! 🔬 CAR-T therapy optimisation - Dr Barnett 🧬 SET gene research - @MariaTeresaEs 🔥 Targeting metabolism - @jbond2019 🔍 Treatment resistance - Prof Turner Find out more at bit.ly/4lBeQKn
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#ESHALL2025 Our Team is ready to welcome you in Malahide, Ireland for the 4th Translational Research Conference on ALL! Registration opens tomorrow at 7:30 am! More information ➡bit.ly/4cy9jAS Chairs: Kathrin Bernt, @CoolsJn @DombretHerve @ullawk #ESHCONFERENCES #LEUsm
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Did you ever wonder why our marrow is located inside of our *bones*, #MedTwitter? There’s no a priori anatomical reason it should be sited there. Blood cells could form in our spleens & livers, as they do during our fetal lives; or elsewhere, as in some animals. Let’s discuss! /1
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