@Passa_lab

A young team at the University of Milan having fun with organic synthesis and medicinal chemistry!

 Department of Chemistry UniMi
sites.unimi.it/passalab/members/
Joined December 2023
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8Media
We are thrilled to announce our latest publication in Nature Communications, detailing the rational drug discovery of new candidates aimed at restoring physiological microtubule interactions. You can have a look at: nature.com/articles/s41467-0… @LaStatale
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Passalab retweeted
EurJOC@EurJOC19 Feb 2024
A Green Approach to Nucleophilic Aromatic Substitutions of Nicotinic Esters in Cyrene by Andrea Citarella, Valerio Fasano, and co-workers (@valeriofasano @Passa_lab @LaStatale) onlinelibrary.wiley.com/doi/…
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Our group exploits the chemistry of boronic acids to access novel functionalized scaffolds!
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We also work on the treatment of neurodegenerative diseases such as retromer stabilization!
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Our group is interested in the development of more efficient methods for the synthesis and functionalization of heterocycles!
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Our research also focuses on the development of novel PROTACs!
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In the last couple of years, we have developed novel SARS-CoV-2 Mpro Inhibitors with Anticoronavirus Activity!
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The total synthesis of natural products, especially cannabinoids, is at the heart of our research!
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A project our group is interested in is the synthesis of self-assembled nannoparticles and conjugates for drug delivery!
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