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Our site was knocked offline earlier today due to a large spike in harmful traffic from Brazil hitting our directory. To alleviate strain on the server and protect our data, traffic from Brazil is temporarily blocked. Our site is now more stable, and we will unblock Brazil ASAP.

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Image of the Week! Submitted by: Yuri Musizzano, M.D. Directory Profile: pathologyoutlines.com/direct… Subspecialty: Placenta Diagnosis: Chronic villitis of unknown etiology with avascular villi #PathTwitter #PathologyOutlines

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Our office is closed today, December 25th. We will return to regular business hours tomorrow, December 26th. ✨ Happy Holidays! #HappyHolidays #PathTwitter #PathologyOutlines

Which of the following is the most likely diagnosis? A. ALK positive histiocytosis B. Erdheim-Chester disease C. Extranodal Rosai-Dorfman disease D. Inflammatory myofibroblastic tumor E. Juvenile xanthogranuloma Answer: buff.ly/3P3clm3 #PathTwitter #PathologyOutlines

Image Quiz! A 41 year old woman underwent a core needle biopsy for a 3 cm breast mass discovered on her first screening mammogram. The lesional spindle cells show the CD68 immunostaining pattern seen below; they are also positive for ALK and negative for SMA and desmin. (Cont.)

Mark your calendar for the Kameda Pathology Seminar, featuring Dr. Nat Pernick as a guest speaker, on December 25 at 18:00 JST! Participate online from anywhere or attend in person in Tokyo. Register for online or onsite attendance: buff.ly/49OSeBC #Pathology #Tokyo

Case: pathologyoutlines.com/caseof…

Although the lesion remained stable over a 1 year follow up, the patient underwent surgery due to an increased frequency of seizures. The lesion was completely removed; the patient is in good health with no evidence of recurrence 1 year after surgery. What's your diagnosis?

Case of the Month: A 32 year old woman with a clinical history of complex partial type seizures underwent a brain MRI, which showed a 2 cm solid cystic lesion without contrast enhancement in the left temporal lobe.

Thank you for being part of our directory, @ashappunnoose86!

Image of the Week! Submitted by: Asha Peedikayil Punnoose, M.D. Directory Profile: buff.ly/4iHMVb1 Subspecialty: Pediatric Diagnosis: Nephroblastoma #PathTwitter #PathologyOutlines #PediPath