
🇺🇸🇩🇪 Claude Code Degenerate. Aerospace, Hardware investor @IndicatorFund. Former Head of Intl and Crypto @robinhoodapp . 出海 investor @plaudAI, @ManusAI
London
Joined August 2007
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Yes, AI is rapidly advancing mathematics (and theoretical physics problems that are essentially mathematical). Like Ramanujan’s notebooks, human mathematicians will spend months (years?) poring over the stream of papers that AI effortlessly generates, hoping to verify and understand them, probably until math itself (via Lean) becomes a branch of computer science like almost everything else.
However, after math and physics, there is still a next scientific frontier: chemistry, and especially biology and medicine.
I mean, it was already the frontier, but it’s the next one too. AI can crush deterministic math problems on the computer, but biomedicine is a highly empirical, noisy, multivariate, and yet often predictable domain.
Thus, AI radically increases our ambitions in biomedicine. All the omics data, all the messy literature, it can all be synthesized and analyzed in a flash. This is what the labs mean when they talk about curing all diseases. The tooling is available to take cracks at biomedical problems previously thought impossible.
Midjourney is doing this, Chan Zuckerberg is doing this, Anthropic is doing this, but there will be so much more.
Patrick retweeted
Replying to @straits_times
Why is everyone acting like this is a forest fire issue when its clearly annual burning of palm oil plantations, by companies domiciled IN Singapore.
what’s the point of diluted, fee-bearing ETF wrappers, when you can just buy perps?
Replying to @financialsamura @nico_laqua
At the moment, the exposures to those two are via total return swaps on the perpetual futures.
Patrick retweeted
Interesting chart.🤔
The seventh edition of our Top 100 Consumer AI Apps is here.
New this time: a revenue leaderboard, alongside the usual web and mobile traffic rankings.
Three years ago we published the first edition. ChatGPT was #1, Claude was unranked, and the entire category was chatbots, image generators, and not much else.
In today's edition:
- ChatGPT still holds the throne, now with 1B+ monthly actives on mobile
- Claude has climbed to #3 on web with nearly 1B monthly visits
- The category has expanded to vibe coding (Lovable, Cursor, Replit), music (Suno), design (Figma), voice (ElevenLabs), video (Higgsfield, Kling), agents (Manus), and even hardware (Plaud)
Full breakdown from @omooretweets: a16z.news/p/top-100-consumer…
Patrick retweeted
Explaining the Catholic Church to Godless AI researchers:
Imagine a lab thats spent 2000 years working on alignment
LFG @BaijuBhatt @TomLinford and team
Reason-1 has successfully separated from @SpaceX's Falcon 9. Cowboy Space is officially in orbit.
Initial operations are underway. Stay tuned for updates.
Another epic exit for the @RobinhoodApp mafia
Big and very exciting news: @parafinHQ is joining @stripe.
We started Parafin in 2020 because the small businesses that power the economy were the hardest ones to finance. Six years later, with $3B+ funded to 60,000+ SMBs, we're taking the mission to Stripe's scale.
Huge congratulations to our team, investors and supporters. To our customers: nothing changes about our commitment to you. It only gets better from here.
More from me, @vineetgoel92, and the team
Use @ManusAI Studio to create your own World of Warcraft Forever tools!
This summer, Manus spun back out of Meta and was repurchased by its existing investors. Chris and I had a choice to get back involved and put our sale proceeds back into the company. We agreed and couldn’t be more excited. We are in the early innings of an agentic future, and Manus is one of the greatest product execution teams we’ve ever met.
We’re excited to see them announce major new products today, including Cue, Manus 2.0, and Manus Studio - all of which sit at the cutting edge of agentic work.



























