@PeTompa

Professor of molecular biology @VIBLifeSciences and @VUBrussel. Cofounder of New Equilibrium Biosciences. Active in the field of #IDPs and #LLPS

 Brussels
tompalab.sites.vib.be/en
Joined December 2022
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Application of polystyrene sulfonate (PSS) for inhibiting toxicity of ALS/FTD-linked dipeptide repeats (#DPRs) biorxiv.org/content/10.1101/… I am thrilled to share our work on targeting #C9orf72 #ALS/#FTD-related #LLPS/#condensation of DPRs by an #FDA-approved drug, #PSS.

Application of polystyrene sulfonate (PSS) for inhibiting toxicity of ALS/FTD-linked dipeptide...

The expansion of GGGGCC (G4C2) repeats in the noncoding region of C9orf72 is the most common genetic cause of familial and sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia...

biorxiv.org
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Peter Tompa retweeted
Tamas Lazar@LazTamas4 Apr 2023
📰📊 Our lab is proud to share a preprint (Van Nerom et al. 2023) about pathological #LLPS of #G3BP1 in presence of #ALS/#FTD-linked PR/GR repeats – a study mainly led by @PeTompa. 🧬🧪🔬
bioRxiv@biorxivpreprint1 Apr 2023
C9orf72-linked arginine-rich dipeptide repeats aggravate pathological phase separation of G3BP1 biorxiv.org/cgi/content/shor… #bioRxiv
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