@PeterOverby4

Danish PhD student at UBC. Researching T1 Diabetes, a Therapeutic pathway promoting β-cell survival.

 Vancouver, British Columbia
Joined October 2018
  • Tweets71
  • Following92
  • Followers150
6Media
Peter Overby retweeted
XX@bcellorg16 Jul 2023
Sporting weekend in TO.
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1/13 I’m excited to share the pre-print of the main part of my PhD project titled “Pharmacological or genetic inhibition of Scn9aprotects beta-cells while reducing insulin secretion in type 1 diabetes” Click here: biorxiv.org/content/10.1101/…

Pharmacological or genetic inhibition of Scn9a protects beta-cells while reducing insulin secretion...

Pancreatic β-cells are critical for systemic glucose homeostasis, and most of them undergo cell death during the pathogenesis of type 1 diabetes. We previously showed that a Na+ channel inhibitor,...

biorxiv.org
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12/13 We propose that Na+ channels play a crucial role in the hyperexcitability observed in beta-cells when exposed to high glucose, and suggest that targeting Na+ channels could be a promising approach to modulate this hyperexcitability.
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13/13 In summary, we believe that carbamazepine have the potential to be promising repurposed drugs for enhancing beta-cell survival in type 1 diabetes. However, it is important to note that further studies are required to optimize the drugs' activity and selectivity.
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Replying to @PeterOverby4
@PeterOverby4 giving his talk at #ABC2023
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Replying to @SisSkovsoe
@SisSkovsoe⁩ and ⁦@PeterOverby4⁩ paper is this week’s Featured Article in ⁦@TheEndoSociety⁩ journal Endocrinology! It describes how a Cre knockin NOD mouse line designed as a research tool actually prevented type 1 diabetes in its own. academic.oup.com/endo

Endocrinology | Oxford Academic

An official journal of the Endocrine Society. Publishes novel research and mechanistic studies on regulation of receptor/hormone signals, gene expression, development, function, and disease at the...

academic.oup.com
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We are hiring a post doc. If you have an interest in Molecular Biology, Primary Cilia, alpha cells and islet biology, this might be the perfect position for you. candidate.hr-manager.net/App…
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Strategic wording from @UBC’s survey on allocation of yet another tuition increase. ‘Understanding’ student affordability? It isn’t affordable. Invest in actually fixing it, which wasn’t an option. Do better. #PhDlife
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🚨🚨The University of Michigan Caswell Diabetes Institute is recruiting new faculty to join us in lovely Ann Arbor. Please RT, apply, or share with colleagues who might be interested! #GoBlue diabetes.med.umich.edu/event…
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Peter Overby retweeted
Jamie Chu@CMJamieChu19 Sep 2022
Excited for all the exciting talks #EASD2022 @EASDnews! Come attend my talk Tuesday, 20th, OP6 11:15 am, titled "Quantification of the dynamics of Ins2 gene activity". Grateful to @JimJohnsonSci and organizers for the opportunity to present! easd.org/virtualmeeting/home…
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