@PetersonLab

Official twitter feed of the Peterson Lab at the University of Massachusetts Medical School

 Worcester, MA
umassmed.edu/petersonlab/
Joined May 2015
  • Tweets276
  • Following329
  • Followers662
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A couple of pics from our lab “Unhappy Hours” the past two weeks. Had to furlough some excellent researchers due to funding ‘issues’ not of my making…
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The PetersonLab is moving to BlueSky! Our X account is going away, so come see us there @PetersonLab.bsky.social
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The PetersonLab just joined Bluesky! Come on over!
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🚨 TENURE-TRACK Faculty Opportunity The Genome Integrity Program @UMassChan umassmed.edu/genomeintegrity… Join us exploring DNA replication/repair with Core services supporting your cutting-edge research. 🔗 Learn more: academicjobsonline.org/ajo/j… #Genomics #FacultyJobs #Research #Science

Genome Integrity

Genome Integrity, UMass Chan Medical School. Genome integrity, DNA, RNA, DNA damage, DNA replication, replication stress, replication gaps (Gaps), single stranded DNA (ssDNA), Double stranded DNA...

umassmed.edu
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UMass Chan Medical represented at the 2023 AAAS Fellows Forum #AAAS #MaryMunson #UmassChan
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BioRxiv: Revised Mechanism of Hydroxyurea Induced Cell Cycle Arrest and an Improved Alternative dlvr.it/T3cq4C
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In @elife: Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C doi.org/10.7554/eLife.94869. Finally out! A great collaboration with Priit Eek and Song Tan.

Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by...

Nucleosome recognition by the SWR1C chromatin remodeling enzyme requires both nucleosomal acidic patches.

elifesciences.org
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Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch dlvr.it/T375vD
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Fantastic cryoEM structure of the SRCAP-nucleosome complex from the Wang and Xu groups. We finally see all the subunits! Yu et al. Cell Discovery (2024) 10:15 Cell Discovery doi.org/10.1038/s41421-023-0…
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Peterson lab “holiday” party. Another great year!
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Peterson lab lunch!
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Only 7 years, but all of these students and postdocs have moved on. One of the satisfying and sad parts of being a PI m.facebook.com/story.php?sto…

Craig Peterson

Peterson lab at Stone Cow Brewery!

m.facebook.com
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Congratulations to Dr Alex Baier - halfway to his MD/PhD!
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We observed how Sirt6 interacts with the nucleosome, by engaging with the DNA, acidic-patch, H3 and H2A C-terminal tail. /3
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The dynamic behavior of Sirt6 provides clues for how it can deacetylate both H3K9 and H3K56 /4
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I’m excited to share a new manuscript on Sirtuin6-nucleosome structure, a result of a great collaboration between @PetersonLab, Song Tan’s, and @valendraica labs. /1 biorxiv.org/content/10.1101/…
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Very very sad news.
J. Tushir-Singh, Ph.D.
@TushirSingh_Lab11 Feb 2023
Just sharing another sad news with the scientific community. The Pioneering molecular biologist Dr. Michael Green, M.D. Ph.D., HHMI and NAS member from Umass Med. School, passed away today with a stroke. Dr. Green revolutionized our understanding of transcription factors. RIP
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Nice to be able to have a lab holiday lunch again!
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Peterson Lab retweeted
Joe Loparo@JoeLoparo18 Nov 2022
This feels like posting into the abyss but for any of you that are still following along... our manuscript with @PetersonLab on the mechanism of SWR1C-mediated H2A.Z deposition is now out in Nature Comms. rdcu.be/cZUup
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Our smFRET study on H2A.Z deposition is finally out in Nature Communications! It took nearly 10 months but I think the final product was worth the pain. Fantastic collaboration with Joe Loparo and Andrew Moreno at HMS. nature.com/articles/s41467-0…

H2A.Z deposition by SWR1C involves multiple ATP-dependent steps

Nature Communications - The multi-subunit SWR1C remodeler deposits histone variant H2A.Z at nucleosomes flanking protein-coding genes. Here the authors use single-molecule and ensemble...

nature.com
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