Medicine, Oncology, Policy host @VPrasadMDMPH https://xitter.cf/t.co/EhAIcGSW2Z @vkprasadlab https://xitter.cf/t.co/7TCrcu2j7V Videos https://xitter.cf/t.co/psQR3fM5V9…

San Francisco, CA
Joined August 2018
In honor of the 1 year anniversary of Malignant book, we are releasing a free, 10 lecture series on cancer, drug policy, & EBM @VPrasadMDMPH gave it to fellows for years! Now to all Here is Lecture 1 - Lay of the Land [Thread will link to all lectures] youtube.com/watch?v=RjS0T_FK…
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“Prespecified descriptive OS analysis.” Those words should give us pause. Calling this a “positive OS result” in a phase 3 trial manuscript is misleading when OS was outside the formal testing strategy. The results are encouraging, but an OS benefit has not been formally demonstrated in this analysis. I’m surprised this framing passed journal review. Oncologists and patients shouldn’t need to close-read a manuscript like English professors to understand whether a trial formally demonstrated an OS benefit. Put the bottom line up front. @Timothee_MD @oncology_bg @SusanGKomen @BCRFcure @OncoAlert @Annals_Oncology @myESMO @ASCO @AACR @SABCSSanAntonio
📢 #ESMO26 concomitant paper - Overall survival with adjuvant ribociclib plus nonsteroidal aromatase inhibitor in patients with high-risk HR+/HER2– early breast cancer: Six-year follow-up of the NATALEE trial. 🔗shorturl.at/AsvoB @LoiSher
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Apparently, following the money becomes less appealing when the trail leads home. This guy’s own family made millions inside the academic biomedical system whose funding arrangements he defends. His mother was a medical school dean at Cornell with a salary near or above seven figures and a lavishly compensated bureaucrat at a Harvard hospital. His father made millions working inside NIH. They were powerful, rich insiders in the establishment he now protects. Now he likely stands to inherit a family fortune. The status quo he promotes made his family rich and could ultimately make him even richer. His outrage conveniently stops at his own doorstep.
He's trying to run, but Congress should not let him hide. Calley Means worked the laws from the inside to benefit his own company, making millions of dollars.
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Calley Means resigns due to frustration with lack of MAHA progress. politico.com/news/2026/10/22…
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Founder Mode: People who cure their own cancer 8 questions to ask
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We have finished sharing our nine free "How to Not Get Fooled by the Medical Literature." Today, on @Sensible__Med, we post the first of nine lecture for paid subscribers. Join us. It is a fun set of lectures. You will definitely learn a ton! sensible-med.com/p/episode-1…
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NEW: A few years ago, Scott Gottlieb was helping the Biden administration censor conservatives on Twitter for Pfizer. Last year, he was saying that Robert F. Kennedy was unqualified and lambasted plans for higher vaccine standards. This year, he's back in the inner circle at FDA. Gottlieb endorsed Overton and his two top aides at FDA spoke with Overton before her confirmation hearing. Kennedy's leadership was once seen as a direct rebuke of the censorship and Big Pharma capture that defined the COVID era. A lot has changed.
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Pope Leo's lung cancer Thoughts not reflected in media reports
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Terrance Tao's Cancer/AI analogy
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Phase 1 trials for medical AI
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My review of You Can See Everything
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Pope Leo's Cancer - 3 possibilities
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For healthy people (or those with common conditions, e.g. HTN), genomic knowledge has little to no practical value via @VPrasadMDMPH drvinayprasad.com/p/genomics…
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Nice little historical reminder from @VPrasadMDMPH that, good as genome sequencing is, the promise of "customized medicines for everyone" has not really come out at all. drvinayprasad.com/p/genomics…
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Define irony, given his role in one of largest research scandals while at Duke documentcloud.org/documents/…
Trust and Science The scientific method is the best tool we have for arriving at truth. It is not much good for building trust — just look at the news. Is there a way to “science” our way to closing the trust gap? #STATSummit
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STAT has turned defending the biomedical status quo into a business model. It convenes conferences to trot out the same failed establishment figures, packages their talking points as news, and publishes hit pieces against people trying to change the system. Now it brings back Califf to disparage DOGE. Apparently talking straight means giving establishment hacks another microphone to explain why disturbing their preferred arrangements is a national catastrophe. I’d be more interested in hearing these people account for their own failed leadership.
The fmr FDA commissioners are ready to, as I like to say, sit crooked and talk straight. Right away, Rob Califf says that he thinks DOGE will go down as “one of the biggest disasters in American history.” #STATSummit
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How did Fauci become the best paid bureaucrat in history? His diary shows he was an expert swamp creature. When he was fighting with CDC Director Rochelle Walensky: - He fed a hit piece about her to the New York Times, then consoled her about that very same New York Times hit piece! - He recommended a top to bottom review of CDC - He went over her head at HHS (Sean Mccluskie) and the White House (Courtney Rowe) for greater control
In his diary, Anthony Fauci called the CDC “truly a dysfunctional organization.” He kept that criticism out of his book, even though he had recommended Rochelle Walensky as CDC director. But he made sure to note it in his diary.
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Interview between @AlexBerenson and @VPrasadMDMPH
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Without the study, 14000 newborns, will go without it for the first 6 weeks.
BREAKING: Hepatitis B vaccine trial backed by RFK Jr. moves forward in Guinea-Bissau, with 7,000 newborns set to go without the vaccine for their first 6 weeks of life.
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"the clinical consequences weren’t measured at all."
Researchers have found that within two months of infection, measles wiped out 11 to 73 percent of the range of antibodies children had acquired over their lifetimes. Our Ask A Doctor columnist explains the consequences of catching measles: wapo.st/4zmSy5Z
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This is why Science does not deserve the enormous amount of federal funding it receives. Rather than focusing on science, its editors promote fluffy, woke commentary about personal identity and social agendas. A scientific journal’s role is to advance science, not lend scientific prestige to the editors’ preferred social causes.
"I did not need to disguise the constraints of my career to prove I was a devoted mother, just as I do not need to disguise the demands of motherhood to prove I am a serious scientist." #ScienceWorkingLife scim.ag/4xUARcY
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