ALT Schematic of proposed cascade. Poly I:C leads to IFNa, which leads to IFNg, which induces CXCL9 in the interfollicular region. cGAMP adjuvant also induces IFNa, IFNg, and CXCL9, whereas adjuvants R848 and Flagellin induce IFNg and CXCL9 only.

ALT Immunofluorescence imaging after intracellular staining in lymph node slices. White outlines of B220+ cells (B cells), with some blue lymphoid cells (IFN-gamma producing) and a few larger, non-lymphoid pink cells (IFN-alpha producing).

ALT Experimental design: Adding IFN-gamma and/or IFN-alpha to the media over ex vivo lymph node slices induced the production of CXCL9 and/or CXCL10 in a dose-dependent manner.

ALT Graphical abstract. Vaccination with poly I:C leads to IFN-alpha and IFN-gamma production, which causes CXCL9 upregulation in the lymph node. In contrast, vaccination with alum does not induce IFN-alpha, IFN-gamma, or CXCL9.

ALT Images of lymph node tissue labeled by immunofluorescence. Breast cancer cell line (BRPKp110) in teal; B cells in green (CD19), lymphatics in purple (Lyve-1), stromal cells in grey (podoplanin).

ALT Graphical abstract: Schematic of photopatterning, with NMR spectrum showing a methacrylate peak going down, and a photopatterned earth that is less stable at higher peak heights and more stable at lower peak heights.

ALT Dedicated two-lane bike lane by the major road.

ALT Bike parking by the Metro and in front of big buildings.

ALT Giant Nutella! (had to show it again)

ALT Bamboo disposable cutlery for takeout food!

ALT Rotterdam's Cube houses! People really live in these.

ALT Mix of old and new architecture in Rotterdam.

ALT Giant Nutella jar with a pump dispenser. Amazing! 😍

ALT Pompano lab poses for Katerina's defense, smiling at camera. Katerina is in the center in white dress.