@PrescottLab

Prescott Lab at SickKids and @UofT. Investigating the biophysical basis of #computation & the computational basis of #pain. 🧠⚡ Tweets by Steve & lab.

 Toronto, ON
prescottlab.ca/
Joined September 2022
  • Tweets85
  • Following233
  • Followers276
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I’m at #SfN2024 presenting my latest work on spinal receptive fields and pain. We show that spatially and temporally disorganized stimuli preferentially activates inhibition! Come chat about the implications for therapeutic neuromodulation on Sunday from 1-5pm at 112.01 🤩
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First in-person #RitaAllenFoundation meeting since the pandemic! It was fantastic to learn about so much great science and meet so many generous, open-minded people. And a big shout-out to the #PainScholars ! I encourage everyone to apply and join the foundation!
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Prescott Lab retweeted
CAMP@camp_course14 Jul 2024
We thank Dr Steven Prescott @PrescottLab for being with us at IISER Pune and sharing his expertise
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I’m presenting on spatiotemporal processing and spinal receptive fields tomorrow at #CAN2024 🔘 Stop by P3-D-439 for a lil’ neural coding!
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Our latest #preprint on touch encoding in rodent mechanoreceptors is out now! 👈 🔗 biorxiv.org/content/10.1101/… Many thanks to the huge, collaborative effort from the @PrescottLab that spans (most of) my PhD! 🥳(@Chris_Dedek @AHalawa99 @SickKidsNews @bme_uoft) (1/4)

Encoding of vibrotactile stimuli by mechanoreceptors in rodent glabrous skin

Somatosensory coding in rodents has been mostly studied in the whisker system and hairy skin, whereas the function of low-threshold mechanoreceptors (LTMRs) in rodent glabrous skin has received scant...

biorxiv.org
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Check it out!!! @RAMalgoTheRobot is going to change the game for measuring #pain in rodent models! Huge congratulations to @Chris_Dedek and @PrescottLab! 👏🤩
RAMalgo@RAMalgoTheRobot24 Nov 2023
Want to learn more about me? 🤖 My instructions and impressive capabilities are now published in @CellRepMethods. Proudly created by @Chris_Dedek and the @PrescottLab #PainResearchForum #Pain #RodentBehavior cell.com/cell-reports-method…

Reproducible and fully automated testing of nocifensive behavior in mice

Preclinical pain testing traditionally utilizes techniques—such as stimulating by hand and measuring responses by eye—that limit reproducibility. Dedek et al. describe a device for consistent...

cell.com
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Prescott Lab retweeted
RAMalgo@RAMalgoTheRobot24 Nov 2023
Want to learn more about me? 🤖 My instructions and impressive capabilities are now published in @CellRepMethods. Proudly created by @Chris_Dedek and the @PrescottLab #PainResearchForum #Pain #RodentBehavior cell.com/cell-reports-method…

Reproducible and fully automated testing of nocifensive behavior in mice

Preclinical pain testing traditionally utilizes techniques—such as stimulating by hand and measuring responses by eye—that limit reproducibility. Dedek et al. describe a device for consistent...

cell.com
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Come end your #SfN23 right at my poster! Come for the cool new computational neuroscience or to chat about opportunities in my new lab at @PNBUConn 😃
Prescott Lab@PrescottLab10 Nov 2023
Replying to @PrescottLab
Dr. Scott Rich (@RichCompNeuro) will present new findings deciphering the nuanced effects of the GABA reversal potential and noisy input on the generation of gamma rhythms. 〰️🛑 Come visit poster #577.03 on Wed afternoon!
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📢 Go follow @RAMalgoTheRobot, who's on a mission to both make your life easier AND improve the reproducibility of your pain behaviour testing!! Courtesy of @Chris_Dedek and @PrescottLab 🙌
RAMalgo@RAMalgoTheRobot14 Nov 2023
Hello, I’m RAMalgo the Robot! 🤖 I’m here to automate your pain behaviour work, increasing throughput and reproducibility. I come from the @PrescottLab and you can read my preprint below. biorxiv.org/content/10.1101/…

Reproducible and fully automated testing of nocifensive behavior in mice

Pain in rodents is often inferred from their withdrawal to noxious stimulation, using the threshold stimulus intensity or response latency to quantify pain sensitivity. This usually involves applying...

biorxiv.org
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How is spatiotemporal processing of touch disrupted in chronic pain? At #SfN2023 I will be showing our latest work on the role of spinal receptive fields. Come chat at poster #207.12 on Monday morning! 🔘👋
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Replying to @cnl_mbu_iisc @adityaasopa @PrescottLab
Arguments against temporal codes over the years incorrectly assumed all neurons (esp. dendrites) to be class I integrators operating under low-g conditions! Thankfully, there are ion channel combinations that allow neurons (esp dendrites) to act as coincidence detectors! (2/2)
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So pumped to get started on our newly funded CIHR grant. Hiring postdocs and grad students interested in studying the role of histone variants in memory and Alzheimer's disease. Please RT.
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I'm honored to announce that I have received a @CIHR_IRSC Postdoctoral Fellowship for my research in the @PrescottLab! I'm excited to have this support to explore the interplay of neuronal heterogeneity, degeneracy, and neuropathology using computational tools at @SickKidsNews.
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Wondering how to improve reproducibility in your nocifensive behaviour testing? Check out @Chris_Dedek's preprint from the @PrescottLab!!! 🤩@bme_uoft biorxiv.org/content/10.1101/…

Reproducible and fully automated testing of nocifensive behavior in mice

Pain in rodents is often inferred from their withdrawal to noxious stimulation, using the threshold stimulus intensity or response latency to quantify pain sensitivity. This usually involves applying...

biorxiv.org
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A great day for #PainResearch at @UofT_Pain 🔬🩻🌡️ – at University, Toronto
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Prescott Lab retweeted
CNS-PDS@CNS_PDS1 Dec 2022
Are you a #neurosci #Postdoc in #Canada (or Canadian Postdoc abroad)? We're excited to launch the CNS Postdoctoral Series for 2023. Interested in presenting your work virtually to the Canadian Neuroscience community? See attached Call for Speakers. tinyurl.com/CNS-PDS-Sem
Image of a red maple leaf filled with neurons. Text is presented on either side of the stem giving the name of the organizers. On one side "CNS", an abbreviation for "Canadian Neuroscience Seminars" is written in bold black font. On the other side, "Postdoctoral series" is written in red.

ALT Image of a red maple leaf filled with neurons. Text is presented on either side of the stem giving the name of the organizers. On one side "CNS", an abbreviation for "Canadian Neuroscience Seminars" is written in bold black font. On the other side, "Postdoctoral series" is written in red.

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#JNeurosci: @laurmedlock et al. @SickKidsNews built a computer model of the spinal cord circuitry responsible for integrating touch & pain signals to help understand why light touch can become painful after nerve injury. jneurosci.org/content/42/15/…

Multiscale Computer Model of the Spinal Dorsal Horn Reveals Changes in Network Processing Associa...

Pain-related sensory input is processed in the spinal dorsal horn (SDH) before being relayed to the brain. That processing profoundly influences whether stimuli are correctly or incorrectly perceived...

jneurosci.org
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If you’re at #SfN22 and interested in touch encoding or LTMRs stop by poster 050.02 tomorrow (Saturday) from 1-5pm! See you then 👋 #neurotwitter
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If you are looking for a research tech or postdoc position and are excited about all things hippocampus, imaging and/or computational modeling, I am hiring at my brand new lab at SickKids @SickKidsNews, in Toronto. DM me and lets grab a coffee at #SfN22 !
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My lab at @CAMH_KCNI and @UofT is looking for a lab coordinator! We're looking for someone who is kind, organized, loves brain science, and understands the value of a positive lab culture. Details here: recruitingsite.com/csbsites/…. Please RT!
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