@ProteomOX
tdi.ox.ac.uk/research/research/tdi-mass-spectrometry-laboratory/mass-spectrometry
Joined August 2022
  • Tweets17
  • Following8
  • Followers36
2Media
Oxford Discovery Proteomics retweeted
CAMS Oxford Institute@CAMS_COI_Ox30 Apr 2024
New paper from COI Researchers @kesslerlabox, @BenediktKessler, @Zhu_L_Oxford, @AndreasDamiano2 identifies Ubiquitin C-terminal hydrolase UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia. Read more here:camsoxford.ox.ac.uk/news/nlr…

NLRP3 Inflammasome “DUBbed” by UCH-L1, affecting IL-1β production in macrophages and microglia

A Cell Reports study led by Prof. Benedikt Kessler provides an intricate time-resolved molecular map of different phases of NLRP3 inflammasome activation and unveils ubiquitin C-terminal hydrolase 1...

camsoxford.ox.ac.uk
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Congratulations to the Kessler group and #proteomics team for their new paper in @LSAjournal doi.org/10.26508/lsa.2023022…
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Fantastic new #ALS paper from our collaborators using #DIA #proteomics of cerebrospinal fluid onlinelibrary.wiley.com/doi/…

Data‐independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and...

Dellar et al. explored the utility of library-free data-independent acquisition mass spectrometry for proteomic profiling of cerebrospinal fluid in amyotrophic lateral sclerosis, achieving high...

onlinelibrary.wiley.com
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Oxford Discovery Proteomics retweeted
Kessler Group Oxford@kesslerlabox24 Jan 2024
Replying to @DrAndyBlackford @MolecularCell
Great collaboration with @DrAndyBlackford and the @ProteomOX team with @Chapman_lab_UK @MRC_WIMM @CAMS_COI_Ox @CmdOxford
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Oxford Discovery Proteomics retweeted
Kessler Group Oxford@kesslerlabox1 Dec 2023
Cutting-edge #plasma_proteomics showcased by Iolanda Vendrell @ProteomOX @CmdOxford @NDMOxford ow.ly/Uf8X50Q6jYu
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Oxford Discovery Proteomics retweeted
Roman Fischer@RomanFi1391177424 Nov 2023
Immensely proud that our story on #spatial #proteomics is finally out! Many thanks to the team, #Bruker, #NatureCommunications and the reviewers …it was quite a journey…much more of this to come! doi.org/10.1038/s41467-023-4… #proteomics #CancerResearch @ndmoxford @proteomox

Deep topographic proteomics of a human brain tumour

Nature Communications - Ultrasensitive, spatially-resolved proteomics techniques allow mapping the organisation of healthy and diseased tissues. Here, the authors develop a workflow for...

nature.com
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thelancet.com/journals/landi… New study helping to differentiate between bacterial infections in febrile children #proteomics #SomaScan #antibiotics

A multi-platform approach to identify a blood-based host protein signature for distinguishing...

This study has led to the identification of a protein signature that could be ultimately developed into a blood-based point-of-care diagnostic test for rapidly diagnosing bacterial and viral infect...

thelancet.com
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Fantastic new #Parkinsons research on #αsynuclein #ubiquitination from collaboration with @GeorgeTofaris lab. Read it at @ScienceAdvances: science.org/doi/10.1126/scia…

Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its...

De novo ubiquitinated α-synuclein is targeted to endosomes via NBR1 and ESCRT I-III for lysosomal degradation.

science.org
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Christmas has come early!🎄🎅🎁 We're unwrapping our new #Thermo #Orbitrap Ascend and Vanquish Neo #proteomics #massspectrometry
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Join us tomorrow at the Bruker Proteomics and PaSER Workshop at the Malmaison Hotel, followed by a tour of the TDI lab! Register here: bruker.com/en/landingpages/b…

eXceed Event: Local Seminars Europe, Middle East and Africa

Join our local seminars taking place in various countries and get first-hand information about Bruker’s latest news for different application areas.

bruker.com
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We're hiring! Looking for a new postdoc to join our proteomics team - apply here: my.corehr.com/pls/uoxrecruit…
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Great new #multiomics #proteomics collab study of #macrophages in #HermanskyPudlakSyndrome #IBD nature.com/articles/s41385-0…

Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to...

Mucosal Immunology - Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism

nature.com
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Two fantastic new #proteomics papers in collaboration with the Vincent/Gentleman and Simon groups at the Kennedy Institute of Rheumatology @KirOxford and @KingsCollegeLon: nature.com/articles/s41467-0… sciencedirect.com/science/ar… @aksimonlab @NatureComms @ActaBio @GentlemanLab

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T...

Nature Communications - Autophagy is known to impact CD4+ T cell proliferation but the identity of autophagosomal components remain unclear. Here the authors leverage a transgenic mouse model...

nature.com
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Oxford Discovery Proteomics retweeted
Kessler Group Oxford@kesslerlabox11 Aug 2022
HT-MS maps the sepsis plasma proteome and clinical subgroups in 2622 patients @proteomOX @KnightGenetics @RomanFi13911774 @philcmsms @CmdOxford @NDM medrxiv.org/content/10.1101/…

High-throughput mass spectrometry maps the sepsis plasma proteome and differences in response

Sepsis, the dysregulated host response to infection causing life-threatening organ dysfunction, is an unmet global health challenge. Here we apply high-throughput tandem mass spectrometry to deline...

medrxiv.org
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The CellenONE has arrived! Single cell #proteomics is coming to Oxford @Cellenion
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Proteomics and proteome network analysis of CSF in ALS patients. Our collaboration with Alexander Thomas and Martin Turner featured in special issue “Multi-omics, Epigenomics and Computational Analysis of Neurodegenerative Disorders”. frontiersin.org/articles/10.…

Frontiers | Network Analysis of the CSF Proteome Characterizes Convergent Pathways of Cellular...

Background: Amyotrophic lateral sclerosis is a clinical syndrome with complex biological determinants, but which in most cases is characterised by TDP-43 pat...

frontiersin.org
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New paper on ELTD1 containing extracellular vesicles inducing angiogenesis in collaboration with Helen Sheldon/Adrian Harris. onlinelibrary.wiley.com/doi/…

ELTD1 is present in extracellular vesicles derived from endothelial cells as a cleaved extracellu...

ELTD1/ADGRL4 is an adhesion GPCR with an important role in angiogenesis. We recently identified a role for ELTD1 in wound repair and inflammation. Activation of ELTD1 in endothelial cells results in...

isevjournals.onlinelibrary.wiley.com
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