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Amazing! 👏👏👏👏 Michigan, get out and VOTE for Mike Rogers on Tuesday. The stakes could not be higher.

🫀 Can coronary atherosclerosis actually regress? Our new randomized FLOWPROMOTE trial analysis, published TODAY in JAMA Cardiology, shows remarkable coronary plaque regression with intensive LDL-C lowering! Atherosclerosis is not necessarily a one-way process. 📄 JAMA Cardiology: doi.org/10.1001/jamacardio.2… #Atherosclerosis #LDL #Cardiology #CCTA

It doesn’t make sense to me that a lake can be that high up.

BREAKING: Star Trek actor Patrick Stewart has died at 86

I'm starting to sense a divide in the tech industry: - People thriving on autonomy who are reinventing how they work and what tools they use with AI: LOTS of work, but they're enjoying it and getting very efficient - People used to being mentored / trained / or simply told what to do and how. Frustrated with the lack of guidance from management on what to do with AI; also frustrated by seeing some of their peers thriving; increasingly bitter about AI and the state of the industry, as a whole Neither group seems to be aware that there's another group, or have empathy for the other group

🚨 South Asians have a heart attack risk double that of Europeans, and standard risk calculators cannot see it coming. Same cholesterol number. Twice the danger. "But the data says otherwise." And no, it is not just genetics. I am a cardiologist. I have treated hundreds of Desi patients with heart disease in their 40s who were told their labs looked fine. 🩺 Here is what the science actually says. The UK Biobank followed patients for 11 years. South Asians had a hazard ratio of 2.03 for heart attack, revascularization, or stroke compared to Europeans. The US and UK risk calculators predicted nearly identical risk for both groups. That gap is why the AHA and ACC added South Asian ancestry as a risk-enhancing factor in 2018. 🔬 Same risk factors. Earlier and heavier. INTERHEART studied 52 countries and found nine modifiable risk factors explain about 90% of heart attacks worldwide. Those factors hit South Asians just as hard per unit. They just show up more often and earlier. Median age of first heart attack is 53 in South Asians versus 58.8 everywhere else. 🫀 The cholesterol myth. A normal LDL number does not mean a safe Desi patient. The INTERHEART lipid substudy found South Asians had the highest ApoB and lowest ApoA-1 of any group studied, for the same LDL reading. ApoB to ApoA-1 ratio predicted heart attacks better than LDL ever could. CETP enzyme activity runs 30% higher in South Asians, even after adjusting for BMI and waist size. 🩺 The thin-fat phenotype. Looking slim does not mean metabolically healthy. South Asians carry more liver and muscle fat and less lean mass at the same or lower BMI. One UK study found 30% more intramuscular triglyceride than BMI-matched Europeans. This starts in the womb. Indian birth cohorts show low birth weight plus rapid childhood catch-up growth predicts adult diabetes and heart disease decades later. 💓 Blood pressure and diabetes move faster. UK Biobank data show South Asians hit systolic 130 by age 40. East Asians do not get there until 49. Nearly 20% of South Asians are hypertensive by 40. The LOLIPOP study found type 2 diabetes three times more common in South Asians, 17.7% versus 5.9%. ⚠️ More events, less visible plaque. SHARE found South Asians had the highest cardiovascular disease rate at 11%, versus 5% in Europeans, despite Europeans showing slightly more carotid thickening. South Asians had higher fibrinogen, homocysteine, and Lp(a). A real clotting tendency, not just plaque volume, drives events. 🔸 Fair counterpoint. When you adjust for 18 risk factors, the excess risk shrinks from 2x to about 1.45x. Genetics found so far look similar to Europeans. Most of this gap is modifiable. A real unexplained residual risk still remains. 🔸 Desi women are under-treated, not lower risk. The DILWALE registry proves it. ❤️ Bottom line: A normal LDL does not mean a safe Desi patient. It is not just genetics. Get ApoB and Lp(a) tested, not just a standard lipid panel. Control blood pressure starting in your 30s, not your 50s. Lift weights. Move more. Eat Mediterranean-style, not low-fat. Use statins, ezetimibe, or PCSK9 inhibitors when the numbers say so. These are proven tools, not supplements promising to clean your arteries. A Kaiser Permanente program targeting these exact factors cut revascularization by two-thirds and mortality by 60%. A patient who gets ApoB tested and treats it aggressively in their 30s can avoid the heart attack that would have hit at 53. That is the difference between prevention and a bypass. If you are Desi and your doctor only checked your LDL, what else are they missing? #Cardiology #HeartDisease #HeartHealth #CardiovascularHealth #ApoB #SouthAsianHealth #Lpa #PreventiveCardiology #MetabolicHealth #LifestyleMedicine

FORBIDDEN STUDIOS PRESENTS: MIGHTY ZION ORANGE RANGER 🍊⚡ Straight from the lost archives of 1995 Saturday morning television. It's morphin' time.

did you know your samsung tv has a service called rmdemon (that's not a typo, demon not daemon) that starts a PACKET LOGGER on your network. what possible legitimate use case could there be here, samsung?

Trying to check if this works.. And shows up as a line of characters cutting across The post #̢̛ͥ̀̽̽ͨ̌̓͆̇̀̽ͦͨͫͯ̏̎̇̈̚͜҉̕͢͏͡҉̸̶̛͢͡҉̵̨̭̳̘̹̫͔͖̜̠͖̫̲̖̱̤̻̖͉͢͞͡ͅͅ͏̸̷̢͑̊̀̐ͣͭͭ̉͂ͨ̽͒̊̎͛ͪ̊̎ͩͧ̀͝͠͠͏̸̵̵̷̵

The local Japanese community wanting reassurance that some foreign property flipper (who never mentions the reason why he's bought & sold all those properties) is not repeating the patterns of foreigners who break property laws is risk management, not open discrimination.

Totally normal. Totally, totally normal.

This is, unreservedly, my favorite account of an ambassador behaving badly, from a diplomatic oral history site. I read this years ago and cannot forget it, and you won’t either. (If they made this a movie, it’d be R rated.) adst.org/2015/06/this-woman-…

🚨#BREAKING: Absolutely WILD footage has emerged from Atlanta where an apartment complex now uses "robot security dogs" to patrol the area at night. The robot dogs also seem to speak in Indian accents to the residents. I've never seen anything like this before... insane!!!

AFTER THE SHIP SANK IN STRAIT OF HORMUZ, THE CONTAINERS RELEASED UNSEALED PERFMUES INTO THE SEA Does MAGA still believe Trump controls the Strait of Hormuz?

Sternenko is now reporting that in the last hour, Starlink restrictions have been tightened further, with communication with drones now being lost at just 60-70 km/h, compared to the earlier 161 km/h.