PostDoc in the Kulathu lab Ubiquitin and friends enthusiast
Dundee
Joined June 2016
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SAVE THE DATE! The @EMBO workshop "Ubiquitin and Ubiquitin-like proteins in Health and Disease" will be on September 2026. Exciting line up of talks and an amazing location!
Organized by @YKulathu @polosimona1 Yifat Merbl and Claudio Joazeiro
#ubiquitin #UBL #Conference
Rachel O Dea retweeted
Interested in Ubiquitin, Parkinson’s disease therapy, mitochondria or DUB inhibitors? This preprint may be for you:
We show how the deubiquitinase USP30 can specifically be inhibited & introduce a framework for DUB ligandability.
biorxiv.org/content/10.1101/…
Thread👇 – with movie!!
Delighted to say I have been awarded a MSCA/UKRI funded postdoctoral fellowship to investigate UFMylation at specific sites with
@YKulathu
. Looking forward to having a new favourite UBL.
@MSCActions
@UKRI_News @mrcppu
Great body of work defining the intricacies of how PLK1 regulates CENP-A deposition at centromeres. Congratulations on the pre-print @DuccioConti and everyone involved!
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Rachel O Dea retweeted
New paper by the @maltegersch group in @angew_chem : N-Cyanopiperazines as Specific Covalent Inhibitors of theDeubiquitinating Enzyme UCHL1 #chemicalbiology #drugdiscovery
onlinelibrary.wiley.com/doi/…
Fantastic work led by Zhou in our group, see below his facile semisynthetic method for fluorescent tools which paved the way for an in-depth understanding of SUMO specificity and revealed some more secrets about my favourite DUBs (USP36 and USP16). @MalteGersch @mpimoph @J_A_C_S
Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases
@J_A_C_S @isciverse #Chemistry #chemed #scicomm #news #Technology #Tech #NewsBreak #research #science #AcademicTwitter
pubs.acs.org/doi/10.1021/jac…
Interested in the secret lives of DUBs (Or what made us so happy)? See below how we characterised surprising activity of 2 DUBs with a toolkit for the Ubl protein Fubi and found a new aspect of a ribosome protein maturation.nature.com/articles/s41589-0… @nature @mpimoph @MalteGersch
Versatile enzymes: Mechanism of Fubi cross-reactive deubiquitinases for ribosomal protein maturation - published by the @MalteGersch Group in @Nature Chemical Biology #ubiquitin #chemicalbiology
nature.com/articles/s41589-0…
Travel has started. Great to be returning to the fantastic Edinburgh DUB focused conference. Looking forward to the stories! @BiochemSoc #biochemevent
Rachel O Dea retweeted
Great #Campuslauf @TU_Dortmund ! We had lots of fun! And congrats to @AliciaPeschel @intein lab who ranked 5th in the women's category! #running
Rachel O Dea retweeted
Big thanks to the organizing committee and CONGRATULATIONS to all the awardees of the Ubiquitin & Friends Symposium 2023 👏👏👏 #ubfriends2023
Thanks so much to the organisers and attendees for the great conference! It was a fun couple of days with inspiring science and people 😊
2 days filled with excellent talks, great posters, exciting science, and lively discussions. It's been such a pleasure and honor to host this amazing crowd of people at our #ubfriends2023 Ubiquitin & Friends Symposium 2023!
Rachel O Dea retweeted
HAPPENING TOMORROW! PhD Researchers and Supporters will be demonstrating outside the library at 11am.
Why should you come? A thread:
#PGRsDeserveBetter
#phdlife
#CostOfLivingCrisis
@PWO_Ireland
@DeptofFHed
@uniofgalway
(1/7)
Rachel O Dea retweeted
Our team cycled 5556 kilometres in 3 weeks at the #Stadtradeln @stadtdortmund We will continue and are already looking forward to the next event! #ClimateAction
Rachel O Dea retweeted
Can’t wait to hear them tell Djokovic tomorrow that his smile has lit up the tournament #USOpen
Rachel O Dea retweeted
ITS OUT!! Go watch the video for ‘Dreams’ here youtu.be/Jv4MYqzg-P4 @SAFEIreland txt SAFE to 50300 to donate 4euro & share open.spotify.com/track/60toI…
Rachel O Dea retweeted
List of virtual and in person conferences/meetings in the field of DNA repair and genome stability: docs.google.com/spreadsheets…
