PhD | Integration of computational approaches with diverse wet lab techniques to develop novel genetically-encoded fluorescent sensors.
Zürich, Schweiz
Joined January 2022
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Interested in neurotransmitters , neuropeptides, GPCRs, and other transmembrane proteins ? The Patriarchi lab is looking for highly motivated PhD students as well as Master students.
Don’t miss that opportunity to work in a pioneering sensor development lab.
👇
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Ralph Gradisch retweeted
Congratulations to this year's Dora Brücke-Teleky Award winners:
🏆 1st prize: Lena Nohava
🏆 2nd prize: @THendrikx1
🏆 3rd prize: @RalphGradisch
On 24 June, they will present their work in the Jugendstilhörsaal at #MedUniVienna. Register now! ➡ bit.ly/3AwLdTD
ALT Lena Nohava, Tim Hendrikx und Ralph Gradisch
Ralph Gradisch retweeted
We're hiring! If you're interested in neuroscience, pharmacology and toxicology, please check out this opportunity to join our team as a PhD candidate: fens.org/careers/job-market/…
We will also be at #FENS2024 in Vienna!
Ralph Gradisch retweeted
Our lab is looking for a part-time (50% FTE) Research Assistant to help out with lab management and cloning. Looking for someone with a MSc degree and good DNA cloning experience. message or email me if interested
Delighted having contributed to this work showcasing the association of de novo variants in GABRA4 with neurological phenotypes.
Hopefully increasing clinical awareness!
nature.com/articles/s41431-0…
Ralph Gradisch retweeted
Our lab is accepting applications for new PhD students to work on super exciting protein engineering projects! Apply :)
Time-lagged Independent Component Analysis and the construction of Markov State Models allowed the quantification of the free energy landscape associated with the serotonin transporter‘s path of occlusion. Congrats to @AlvesLeti95 and @lazzarin_erika!
onlinelibrary.wiley.com/doi/…
Our recently published article in @NatuComms is receiving attention !
Link below : 👇
The principles of #serotonin transport have been identified by a research group led by Thomas Stockner from #MedUniVienna, creating a potential basis for the development of novel drugs with improved selectivity and fewer adverse effects. ➡ bit.ly/3UsBjPu
@NatureComms
Interested in the opportunities and advancements of GPCR-based genetically-encoded fluorescent indicators ? Must read !
Happy to see our new Review out!
Engineering, applications, and future perspectives of GPCR‐based genetically encoded fluorescent indicators for neuromodulators - Rohner - Journal of Neurochemistry - Wiley Online Library onlinelibrary.wiley.com/doi/…
Ralph Gradisch retweeted
An amazing collaborative paper from my time as PhD within the @MoltagDK was published today in @NatureComms! Thanks to everybody involved, especially @RalphGradisch, for the excellent teamwork!🎉
Check it out here 👇⚗️
#chemistry #research #natcomm
nature.com/articles/s41467-0…
Ralph Gradisch retweeted
Happy to share our most recent publication. we found that mephedrone induces partial release via the human dopamine transporter- but full release via via the human serotonin transporter. With @MarcoNiello @SitteHarald @gwrud sciencedirect.com/science/ar…
Finally, our preprint got published online!
A wonderful collaborative work proposing a ligand coupling mechanism of the serotonin transporter that distinguishes substrates, partial substrates, and inhibitors!
Here’s the link:
researchsquare.com/article/r…
Ralph Gradisch retweeted
We are looking forward to seeing you in Sunday River for the 2024 GRC on Membrane Transport Proteins!
Great Science, Great Community, lot of fun! 🤯
Registration and details here:
grc.org/membrane-transport-p…
grc.org/membrane-transport-p…
Join us for the 2024 Membrane Transport Proteins GRC July 21-26 in Maine, USA! @GordonConf @Khoshbouei_lab @hannepoulsen @MarcoNiello @OlgaBoudker @zfreyberg @BotanicGeek @martens_chloe @camcdevitt @JoeMindell @kenton_swartz @LabPinkett @e_girardi @DrSusieLIngram1 @JavitchLab
It’s always nice watching @MarcoNiello rocking the stage talking about the dopamine transporter and psychoactive drugs 🤟
Perfectly organised by @SitteHarald @NeuroTransETN
#BrainInFlux #Gaia #Porto
Ralph Gradisch retweeted
Interested in living in Copenhagen? We are hiring!
Open position as a PhD student with interests in the structure and function of the human dopamine transporter. Please share.
@neuroscience_dk @UCPH_health
candidate.hr-manager.net/App…
Ralph Gradisch retweeted
Retweets are welcome and of course applications, especially from female students! :)
If you know someone looking for a PhD to develop #ML methods for chemical applications, preferably photochemistry, spread the word! tinyurl.com/2p935dfv
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Ralph Gradisch retweeted
The first non Tool-dev paper from our lab. With super postdoc Masaya Harada and in collaboration with @DeBurdakov we investigated DA inputs in the LH
Stimulation of VTA dopamine inputs to LH upregulates orexin neuronal activity in a DRD2-dependent manner biorxiv.org/cgi/content/shor… #bioRxiv
Exceptional place, exciting talks as well as discussions - with amazing friends @MarcoNiello @felixpmayer @lazzarin_erika ! Thanks to the organisers and whole serotonin society @5HT_Society !!
Looking forward to seeing everyone in Vienna.
Transporter addicts, attention! Fresh off the press @NatureComms : first structural insights of the SLC22 family - OCT3 (SLC22A3)
nature.com/articles/s41467-0…
Congrats to all collaborators 🥳
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Ralph Gradisch retweeted
We have an open Postdoc position in lung cancer at the Medical University of Vienna, Vienna, Austria
Apply here!
fwf.ac.at/en/service/fwf-job…
Please, RT
