Boliviano & Paceño Bolivarista, aventurero, padre Biomedical scientist, world citizen, coffee addict, soccer & tennis fan Opinions are my own

Montréal, Québec
Joined April 2016
Congrats to the team at @ArrowheadPharma! This is a major milestone in the field, with opportunity for continued improvement! Great news for patients!
Today we announced interim Phase 1/2a clinical data for ARO-MAPT. The results represent an important step in clinical validation of our TRiM platform for delivering siRNA to the central nervous system. Join today’s webinar to learn more: bit.ly/3VMXyCD
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A united Canada is a stronger Canada. 🇨🇦
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$ARWR stunning data. Exceeds all expectations. Time for reflection.
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Seriously, let’s find #Exercizumab!🏃‍♀️ Over a year since the landmark @CDNCancerTrials #CHALLENGE study was published @NEJM …and we can’t seem to implement! Thanks to @nytimes for keeping this in front of the public and our patients. It Can Keep Cancer in Remission. Why Is No One Talking About It? nytimes.com/2026/10/06/well/…
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📣Lung Ambition Awards Announcement: Meet the 2026 Lung Ambition Awards Winners! Learn more about the Canadian-based program and the research that is focused on improving equitable access to #lungcancer care and diagnostics. youtu.be/QF2OqHGb2z8 @AstraZenecaCA @LungAmbition
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Lung cancer patients who received an mRNA COVID-19 vaccine within a few months of immunotherapy lived nearly twice as long as unvaccinated patients. sciencenews.org/article/canc…
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Could your skills help strengthen Canada’s economy and public services? We are seeking experienced professionals in these categories: • health care and social services professionals • medical doctors, researchers and senior managers with Canadian work experience • tradespersons • educators • professionals in science, technology, engineering and mathematics (STEM) occupations • professionals in transport occupations • workers with French-language proficiency Learn more about Express Entry categories: bit.ly/3SX2ujF
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RNA therapeutics: current status and future directions nature.com/articles/s41392-0…
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$ALNY first to liver $ARWR first to lung $ALNY first to intrathecal CNS $ARWR first to adipocytes $ARWR first to CNS via subQ?
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$ARWR presented at Cantor today. CFO Daniel Abel and our top shot, Andy Davis, SVP, Cardiovascular/Metabolic Franchise Head were present. My takeaways: 👉 if FDA would approve PlozaSiran for sHTG today, we would be ready to launch 👉 product ready, sales team ready, processes ready, 20'000 doctors identified, thousands of patients known, very good feedback from payers - not just for FCS patients, even if we look for sHTG patients! 👉 we will start focusing on patients above Trig's 880 (1 Mil US patients) but we hear that doctors also want to prevent first AP for patients between 500 - 880 Trig's!! 👉 NO! licensing deals planned, maybe for some smaller markets. We sell PlozaSiran and ZodaSiran on our own!! Good thing! 👉 PlozaSiran is REALLY superior than tryngolza 👉 We are excited about DimerPA, AROMAPT, AROINHBE and AROALK7! 👉 No changes in data disclosure for those 4 candidates 👉 September for DimerPA and AROMAPT 👉 Q4 for ALK7 and INHBE
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A Canadian economy that could be expected to shrink with the growing hostility of its largest trading partner is instead growing stronger. thestar.com/business/opinion…
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Canada has what the world wants. And the world is choosing to invest in Canada.   In 2025, Canada attracted $93.2 billion in foreign direct investment – our best year for FDI in nearly two decades.   That investor confidence reflects Canada’s strengths: our position as a stable and reliable trading partner, a highly educated workforce, abundant natural resources, and access to 51 global markets and 1.5 billion consumers.   We’re building on that momentum by hosting the first-ever Canada Investment Summit this fall – bringing together global investors to unlock new opportunities, strengthen partnerships and reinforce Canada’s position as a premier destination for investment.   Read the FDI Report 2025: investcanada.ca/FDIReport202…
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$ARWR great to see that Co today did not inflate (initial) plozasiran sales potential: >880 and 500-880 with prior Hx. It's all up to execution now and maybe look beyond US. I also expect a few off-label 500-880 uses out of the vast pool of sHTG subjects. If I had 800, but no prior Hx, I'd want to do anything to avoid painful AP. Rare to see such honesty. Sign of confidence.
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Breaking News: At the European Society of Cardiology Congress (ESC), we presented Phase 3 SHASTA-3 & SHASTA-4 data demonstrating our investigational siRNA therapy reduced acute pancreatitis events in patients with severe hypertriglyceridemia. Learn more: arrowheadpharma.com/en-us/ne…
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The name Lake Ontario comes from the Wendat word Ontari’io, which, appropriately, means “the lake is beautiful, the lake is big”. The name is more than 400 years old, predating both the Confederation of Canada and the Declaration of Independence of the United States of America. We know that America is changing. Their trading relationships, their foreign policies, their national monuments, their hydronyms. Canadians also know that naming reality means calling it Lake Ontario – then, now and always.
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We are looking for skilled workers to help strengthen the Canadian economy and address labour shortages in key sectors. Here are the Express Entry categories where we are seeking experienced professionals to compliment our workforce: • medical doctors, researchers and senior managers with Canadian work experience • health care and social services professionals • tradespersons • educators • professionals in science, technology, engineering and mathematics (STEM) occupations • professionals in transport occupations • workers with French-language proficiency Find out how Express Entry category-based rounds of invitations work: bit.ly/3SX2ujF
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