What will it take to turn AI-designed molecules into antibiotics that reach patients? In our new piece in @ScienceTM @NewsfromScience, we discuss how AI is helping us discover and design small-molecule and peptide antimicrobials, and the work still needed to bring them to the clinic. Better data, rigorous testing, and careful evaluation of safety will be essential, alongside clear regulatory pathways. We want to use machines to better understand biology and turn that knowledge into new treatments for drug-resistant infections. This will take people working together across disciplines. Many thanks to Aarti Krishnan, @Hanqun_CAO, and James J. Collins for the fantastic collaboration. Read: science.org/doi/10.1126/scit… @CBE_Penn @PennMicro @UPennIBI @UPENN_ITMAT @pennbioeng @PennEngineers @PennChemistry @PicsUpenn @MIT_IMES @MITdeptofBE @MITEngineering @wyssinstitute @broadinstitute