@RichJBennett

Professor in the Molecular Microbiology and Immunology Department at Brown University

 Providence, Rhode Island
Joined October 2022
  • Tweets31
  • Following101
  • Followers109
3Media
The strategy behind one of the most successful labs in the world nature.com/articles/d41586-0…

The strategy behind one of the most successful labs in the world

Nature - One UK institute has produced a dozen Nobel laureates and biomedical breakthroughs across the board. How does Cambridge’s Laboratory of Molecular Biology do it? Our study found out.

nature.com
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Mihalis Lionakis@LionakisLab30 May 2024
Thanks @NIAIDNews for highlighting our work and for creating an environment where this bench-to-bedside work can be done!
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New Research Briefing ‘The meaning of oral bacteria in faeces’ out now. By Chen Liao & Joao Xavier. nature.com/articles/s41564-0…
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Are all microbial domination states in the intestine similar? Do all domination states predict disease & infections? Check out the @MSKCancerCenter collaboration below. @cliao345 @T19R84 @TheXavierLab @BingZhai Ana Djukovic @tsonipeled @vandenBrinkLab nature.com/articles/s41564-0…
Chen Liao@cliao3452 May 2024
Our paper on the meaning of oral bacteria in feces is out in @NatureMicrobiol ! We suggest their increased relative abundance in the gut is due to depleted gut-resident bacteria, not their active growth. Huge thanks to @T19R84, Ana, @tmhohl71, Joao, and all collaborators!
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Was awesome having Dr. Lewis Lanier (UCSF) present the third annual Dr. Christine Biron Lecture at Brown University this week and giving the history of NK cells - from their slow start to their meteoric rise! @ImmunologyAAI @brown_mmi
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Identification of an active RNAi pathway in Candida albicans | PNAS pnas.org/doi/10.1073/pnas.23…

Identification of an active RNAi pathway in Candida albicans | PNAS

RNA interference (RNAi) is a fundamental regulatory pathway with a wide range of functions, including regulation of gene expression and maintenance...

pnas.org
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Michael Fischbach
@mfgrp11 Apr 2024
How to pick a problem. Today in @CellCellPress. 1/53 cell.com/cell/fulltext/S0092…

Problem choice and decision trees in science and engineering

Scientists and engineers often spend days choosing a problem and years solving it. This imbalance limits impact. Here, we offer a framework for problem choice: prompts for ideation, guidelines for...

cell.com
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NOA - thrilled to begin a P01 with @AndrewKohLab @RichJBennett @TheXavierLab @LHooperLab and Matt Anderson (U. Wisc) to unravel how Candida interacts with the GI tract. We'll be recruiting to our collective 🍄 team. Thanks @mycoconnection for guiding us in this 2 yr odyssey. 🍾
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Check out this new article on the rapid evolution of a multicellular morphology in Candida auris. nature.com/articles/s41467-0… Congratulations @Guanghua11 @craiglewisennis and all authors!
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Hyphae promote Candida albicans fitness and commensalism in the gut nature.com/articles/s41579-0… This study shows that hyphae formation is critical for Candida albicans gut colonization in the presence of commensal bacteria owing to the production of a hyphal-associated factor.
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Richard Bennett@RichJBennett7 Mar 2024
Does filamentation and toxin production provide a benefit to the fungal pathogen Candida albicans? We investigated these properties of Candida while examining its ability to colonize the gut....
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nature
@Nature7 Mar 2024
Nature research paper: The hyphal-specific toxin candidalysin promotes fungal gut commensalism go.nature.com/3P9XarK

The hyphal-specific toxin candidalysin promotes fungal gut commensalism

Nature - Both the yeast and hyphal forms of Candida albicans enable colonization of the mammalian gut, with hyphal cells secreting the toxin candidalysin to inihibit bacteria and support fungal...

nature.com
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Does filamentation and toxin production provide a benefit to the fungal pathogen Candida albicans? We investigated these properties of Candida while examining its ability to colonize the gut....
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We show that filamentation by Candida can help it compete with bacteria in the gut, and this is due to factors such as the toxin candidalysin. We propose that this toxin has a direct role in inhibiting commensal bacteria thereby helping the fungus colonize the gut.
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This work helps explain how filamentation and candidalysin toxin provide a fitness benefit to fungal cells in the gut. Heartfelt thanks to all who contributed! @brown_mmi @sircaik @OG_coreyfrazer @BrownMedicine
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cool new less/non-toxic polyene—looks very promising! nature.com/articles/s41586-0…
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Gordon Brown@gordon_d_brown28 Jun 2023
Wonderful to have @judithberman11 join the @MRCcmm family.
MRC Centre for Medical Mycology@MRCcmm27 Jun 2023
The MRC Centre for Medical Mycology is proud to announce the appointment of @judithberman11 as an Honorary Fellow. sites.exeter.ac.uk/medicalmy…
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Mihalis Lionakis@LionakisLab22 May 2023
1/3 Thrilled to share our new paper in @CellCellPress led by @jigarvdesai on how complement component C5 promotes phagocyte survival and effector functions for protective antifungal host defense. Read here: sciencedirect.com/science/ar…
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Minju Kim@MinjuKim_uga17 May 2023
It was an amazing opportunity to give a talk in #Candida2023 representing Mitchell lab and to meet fantastic Candida people. 🍄
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