Group Leader—Developmental Molecular Genetics Lab and NHMRC Emerging Leadership Fellow at Mater Research Institute-UQ. Mama of 2. She/her. Views my own.
Brisbane, Queensland, AUS
Joined May 2009
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🐭🧬Our paper on locus-specific mouse L1 activity and regulation, led by the indomitable @Patricia_Grds is out @genomeresearch!🧬🐭
This study evolved from a simple question: what defines the mutagenic potential of a new L1 copy in vivo?
genome.cshlp.org/cgi/content…
A thread:
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Congratulations to multi-talented PhD student Renee Chu, who won the overall competition AND People’s Choice at the @UQmedicine 3MT final, using a thoughtful analogy to describe her research on jumping genes in early development 🧬🧫
Renee will represent @materresearch, @UQmedicine, and #mobileDNA enthusiasts everywhere at the University final later this year! #scicomm #3MT
Sandy Richardson retweeted
The impact of LINE-1 retrotransposons on neurobiology is not fully understood. Our new research in @NatureNeuro sheds light on LINE-1 activity in PV interneurons, sparking fresh perspectives on its role in neurobiology. #neuronaldiversity #neurogenetics
nature.com/articles/s41593-0…
Sandy Richardson retweeted
The Andalusian Government (south Spain) has opened a call for 3-year postdoctoral positions.
If you would like to join my lab at the @ipbln_csic in Granada to investigate the regulation and impact of human mobile DNA, please contact me with an EOI.
See more details below.
Sandy Richardson retweeted
Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites dlvr.it/T2nkWJ
Sandy Richardson retweeted
Interested in L1 retrotransposon regulation in development?
Check out AEpiA member @RichardsonL1Lab's recent paper in @genomeresearch "Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development"
genome.cshlp.org/content/ear…
Sandy Richardson retweeted
Illuminating talk by @RichardsonL1Lab
Transcriptional regulation of Heritable activity of L1 activity in preimplantation embryonic development
Work of @Patricia_Grds from @Faulkner_Lab group
#EMBOMobileGenome
Together, our results suggest an interplay between L1 transcription initiation and de novo DNA methylation during differentiation in the early embryo, potentially involving YY1 or its binding sites within the L1 5’UTR.
Excited to gain mechanistic insight into this process!
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This study represents a huge amount of work by @Patricia_Grds, @Faulkner_Lab, and the most wonderful group of co-authors you could ask for: @Dory_genome, @MischaLundberg, @FranciscoJSL2, @gabriela_bodea, @_adamewing.
💗 and gratitude to all involved!
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