Senior Research Fellow @ University of Otago | Studying CRISPR | 🇳🇿
Dunedin City, New Zealand
Joined July 2017
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It's out🎉Super happy to share our story on the incredible #CRISPR-Cas I-D complex and its mysterious small subunit. Excellent work by @Tess_M_McBride & @AtomicPaparazzo. Shout-out to @davidwtaylorjr, @akhello & @PeterFineran! sciencedirect.com/science/ar…
Rob Fagerlund retweeted
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs.
Plant, Bacterial, Archaeal Bioeng
Custom Lab Hardware
Turn Key Genetic Design
Please RT 💚
Rob Fagerlund retweeted
Deadline Extension for Abstract Submissions
Good news! The deadline for abstract submissions has been extended to Monday 28 October. This is your chance to showcase your research by submitting either an oral or poster presentation for CRISPR 2025.
#crispr #crispr2025 #phage
Rob Fagerlund retweeted
Happy to share our latest story revealing how type III CRISPR-Cas ancillary effectors tactically inhibit translation to combat phage infections: science.org/doi/10.1126/scie…. Here is a thread covering major points: (1/9)
Rob Fagerlund retweeted
If you're after some light reading to start your week, here's a short piece I wrote for The Conversation (@ConversationEDU) on our recent anti-#CRISPR regulation work and its relevance for understanding #phage–host interactions:
theconversation.com/viruses-…
Congrats @ShaharnC 🙌🙌🙌
Congratulations to @ShaharnC from @microtago, @otago, 🇳🇿, who was awarded an IUBMB Travel Fellowship to present her research at the @bmh2024Melb Congress in Melbourne, 🇦🇺.
Rob Fagerlund retweeted
👋🏻 I'm absolutely glee-ridden to finally see our study on the RNA- and DNA-binding anti-CRISPR repressor Aca2 published in @Nature. 🥳 This unassuming little helix–turn–helix protein packs quite the punch! 🧶👇🏻
rdcu.be/dNl45
Rob Fagerlund retweeted
Couple of recent publications from our group!!
1) Awesome work from post-doc Will Jowsey showing how drug-resistance in Mtb alters tolerance to cell wall inhibitors!
doi.org/10.1093/jacamr/dlae0…
(1/2)
Rob Fagerlund retweeted
In our new paper at Cell (@CellCellPress), we reveal secrets of how the third form of life, archaea, make energy. We uncover new lineages of hydrogen-using enzymes, both minimal and complex. These help archaea thrive in all sorts of extreme environments. sciencedirect.com/science/ar…
Rob Fagerlund retweeted
🎉 Excited to share our latest paper in @cellhostmicrobe! Huge congrats to amazing co-first @FabBenz & @SarahCamara94 (in my profile pic! 🥂) for pushing this work from start to finish! 🚀
1/5
🔗sciencedirect.com/science/ar…
Rob Fagerlund retweeted
Excited to see our work out now in @cellhostmicrobe ! 🤩 huge team effort, kudos to everyone involved, especially @FabBenz & @rafapinilla92 ! 🫶
🎉 Excited to share our latest paper in @cellhostmicrobe! Huge congrats to amazing co-first @FabBenz & @SarahCamara94 (in my profile pic! 🥂) for pushing this work from start to finish! 🚀
1/5
🔗sciencedirect.com/science/ar…
Rob Fagerlund retweeted
I am thrilled to share my latest work, out today in @Nature. This project started ~18 months ago as a blueprint for my own lab, which will start at @ISTAustria in July, but not have been possible without the support of @davidwtaylorjr & the whole team
nature.com/articles/s41586-0…
Rob Fagerlund retweeted
I'm so happy to share our SpRY-Cas9 story in its final form! Congratulations to first author @GraceHibshman - it was a great collaboration with a diverse team led by @davidwtaylorjr, including @IlyaFinkelstein and many others... 1/n
rdcu.be/dGkLq
Rob Fagerlund retweeted
A couple of delays, but finally managed to attend my induction as a new Fellow of the Royal Society of New Zealand @royalsocietynz @microtago @otago Thanks to all the students, staff and collaborators who enable us to do fun research!
Rob Fagerlund retweeted
Cellular repair of DNA breaks enables editing of the human genome.
Do human cells repair RNA breaks, and can we use it to edit transcriptomes?
Our work with @ANemudraia and @WiedenheftLab is now online in @ScienceMagazine!
#ScienceResearch
science.org/doi/10.1126/scie…
Rob Fagerlund retweeted
Great to see this out! Always a great time working with the dream team @davidwtaylorjr @PeterFineran @palermo_lab @RobFagerlund and my co-first authors @EvanASchwartz and Mohd Ahsan.
Great work by former grad student @EvanASchwartz and postdoc @jpkbravo @TexasScience @ut_mbs and Mohd Ahsan @palermo_lab in @NatureComms! Couldn’t happen without long time collaborators @RobFagerlund and @PeterFineran @otago. link.springer.com/10.1038/s4…
Rob Fagerlund retweeted
Great work by former grad student @EvanASchwartz and postdoc @jpkbravo @TexasScience @ut_mbs and Mohd Ahsan @palermo_lab in @NatureComms! Couldn’t happen without long time collaborators @RobFagerlund and @PeterFineran @otago. link.springer.com/10.1038/s4…
🤩 Excited to share our story on the special type III-Dv CRISPR-Cas system 😎 This system has many interesting features, like multiple gene fusions that simplify the protein and crRNA components, programmable RNA cleavage and a neat seed window for target specificity...
Great work by former grad student @EvanASchwartz and postdoc @jpkbravo @TexasScience @ut_mbs and Mohd Ahsan @palermo_lab in @NatureComms! Couldn’t happen without long time collaborators @RobFagerlund and @PeterFineran @otago. link.springer.com/10.1038/s4…
Further, using a combo of structural, biochemical and molecular dynamic approaches, we show new insight into how type III systems cleave RNA 😱 A must read for type III aficionados 🤓 I hope you enjoy 🎈
This was a fun collaboration with @davidwtaylorjr @palermo_lab @PeterFineran with brilliant work by first authors @EvanASchwartz @jpkbravo @Ahsan09966804 🙌