@RoopsieK

Integrated Ph.D. student @SamratLabMohali @IiserMohali

sites.google.com/view/roopali-khanna-iiser-mohali/home
Joined April 2021
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  • Following529
  • Followers354
Gorgeous academic block and library area of our beautiful IISER Mohali campus in the twilight as dusk fell after a rainy day.
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Indranil Banerjee@indranilb4uSep 20
Delighted to share our latest publication in EMBO Reports, led by @kajalGupta1995 Here, we identify the WASH complex as a previously unknown mediator of flu virus entry and reveal how TRIM62 regulates this complex. @DBS_IISERM @IiserMohali @emboreports link.springer.com/article/10…

TRIM62 facilitates influenza A virus entry by regulating WASH-dependent endosomal trafficking

EMBO Reports - Endocytosis enables efficient cargo uptake while restricting uncontrolled cellular entry, yet how this balance is enforced during endocytic uptake remains poorly understood. Using...

link.springer.com
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Santosh Satbhai@santosh7bhaiSep 11
Honoured & happy to share dat my profile article is published in @NewPhyt A privilege to have my research journey & work featured in such a prestigious journal. Gr8ful to everyone who has supported & inspired me along d way. @sbslab_IISERM @IiserMohali doi.org/10.1111/nph.71582

Santosh B. Satbhai

Santosh B. Satbhai, Indian Institute of Science Education and Research (IISER) Mohali (India).

nph.onlinelibrary.wiley.com
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Happy to share our Indo-French @IFCPAR collaborative work on Henipavirus IDPs with @LonghiSonia & coworkers in Montpellier & Marseille published in Protein Science. Congrats to @Harshita3110 (my former BS-MS student), @anuja_walimbe & colleagues in France. onlinelibrary.wiley.com/doi/…
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Happy #FluorescenceFriday! Sharing a picosecond time-resolved confocal fluorescence image & decay profiles of nucleoli (granular component) in a live mammalian cell recorded on a time-resolved single-molecule confocal fluorescence microscope in our lab by @Arpita195 & @RoopsieK.
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Sayanta Mahapatra@DrSMahapatraJun 16
A novel recipe to obtain ultra-pure full-length Tau for co-factor-free/induced aggregation for high-res studies. Thanks @WalczakMAA, co-lead Ruiheng, and co-authors
https://www.cell.com/star-protocols/fulltext/S2666-1667(26)00270-4

ALT https://www.cell.com/star-protocols/fulltext/S2666-1667(26)00270-4

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Happy to share our latest preprint. biorxiv.org/content/10.64898…
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Dr. Arpita Singh @Arpita195 (National Postdoctoral Fellow in our lab) is attending an EMBO Symposium on "Cellular Mechanisms Driven by Phase Separation" starting today at EMBL Heidelberg, Germany. She will present her new results on nucleolar condensates. embl.org/about/info/course-a…

Cellular mechanisms driven by phase separation

embl.org
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Swastik PG@PgSwastikMay 18
Thrilled to share my first first-author preprint from my PhD! 🎉 We asked, can a low cost, FDA-approved α1-AR blocker reverse Alzheimer's disease at the molecular level? In the TgF344-AD rat model: YES- and the effect is strikingly sex-dependent. bioRxiv: biorxiv.org/content/10.64898…
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Catalyst@ayusmansenMay 5
Great work by @ShandilyaEkta and @Xiaotianlxt. From passive, receptor-based delivery to dynamic, energy-responsive targeting. Chemotaxis of ATPase-Powered Nanoparticles up Extra- and Intracellular ATP Gradients | Nano Letters pubs.acs.org/doi/10.1021/acs…

Chemotaxis of ATPase-Powered Nanoparticles up Extra- and Intracellular ATP Gradients

Abstract. Guiding synthetic nanomaterials toward specific cells and subcellular organelles remains a critical challenge for targeted therapeutics. Here, we

pubs.acs.org
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In a collaborative study led by @Krishanpal_K published in @CellReports, we show that phase separation of Plasmodium falciparum Heterochromatin Protein 1 is essential for heterochromatin formation and malaria virulence gene control. Congrats to the team!! cell.com/cell-reports/fullte…
Krishanpal Karmodiya@Krishanpal_KMar 22
Excited to share our latest work @CellReports! We show how PfHP1 phase separation is key to malaria virulence gene control. cell.com/cell-reports/fullte… Brilliant work by @MamatharaniV & the team. Thx @mahipal_ganji, @SamratLabMohali & Till Voss for a great collab! Thx @IISERPune.
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To all our dear friends, colleagues, students, staff, collaborators, supporters, well-wishers, and academic associates: Wish you and your family a very happy, prosperous, productive, peaceful, joyous, and healthy New Year 2026. - The Mukhopadhyay Lab
Samrat Mukhopadhyay@SamratLabMohali29 Dec 2025
On this day, 17 years ago, Dec 29, 2008, I joined the IISER Mohali faculty. It's been an exciting journey. I learned a lot from many whom I interacted with. My students have made my scientific expedition very enjoyable. My experience has surpassed my expectations. Thank you all🙏
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Catch our latest publication in @NatureComms where Indigo, a classic dye is reimagined as an extreme photocatalyst with a very broad excited state redox window @DCS_IISERMOHALI. Huge thanks to @dm_lab for his initial support. nature.com/articles/s41467-0…

Dramatic expansion of bimodal redox window of indigo by two-electron redox processes

Nature Communications - Indigo is an extremely popular molecule in dye industry, however, its use in photochemical transformations is surprisingly scarce. This report explores its photocatalytic...

nature.com
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Miao Yu@MiaoooYu13 Dec 2025
How liquid-like is the nuclear pore barrier?🍝𖣐 Our new preprint shows that FG-NUPs exhibit nanosecond-scale, liquid-like mobility in living cells. 💧⚡O-GlcNAcylation and an importin-β gradient keep the FG network liquid-like, reconciling nuclear pore complex models.
bioRxiv Biophysics@biorxiv_biophys12 Dec 2025
O-GlcNAcylation and an importin-β radial gradient keep the FG barrier liquid in live-cell nuclear pores biorxiv.org/content/10.64898… #biorxiv_biophys

O-GlcNAcylation and an importin-β radial gradient keep the FG barrier liquid in live-cell nuclear...

The nuclear pore complex (NPC) regulates the molecular traffic between nucleus and cytoplasm.[1][1],[2][2] Its permeability barrier is formed by intrinsically disordered proteins (IDPs) known as...

biorxiv.org
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Proud to share our new study nw online in @NewPhyt! We showed dat the PEP2–PEPR2 signaling module plays a key role in Fe-deficiency responses and root growth in Arabidopsis. Gr8ful to @DBTIndia for the support. @DBS_IISERM @IiserMohali doi.org/10.1111/nph.70792 @sbslab_IISERM

Danger‐associated peptide modulates iron deficiency signaling and root growth in Arabidopsis

Iron (Fe) is an essential micronutrient for plants and humans, with plants being a primary dietary Fe source. Fe availability significantly affects plant health, development, and yield. Its deficie...

nph.onlinelibrary.wiley.com
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Happy to share our latest paper published in PCCP (Physical Chemistry Chemical Physics) @PCCP @RoySocChem. Congratulations to my PhD student, @Jaspreet_Tiet @TIETofficial. Thanks to ANRF-POWER and MoE-STARS for supporting our research. Here's the link: pubs.rsc.org/en/content/arti…
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Subhabrata Maiti@Subhachem12 Nov 2025
Happy to share our just published @NatureComms article from @IiserMohali @DCS_IISERMOHALI Thanks to @ANRFIndia for funding. Hard work done by @Rishiram7777 Niranjani @NandhaEttikkan #ReactionDiffusion based system nature.com/articles/s41467-0…

A chemoenzymatic reaction-diffusion system with local inhibition and distal activation

Nature Communications - Achieving spatiotemporal gating of signals is desirable for mimicking of biological processes, but is challenging to achieve in synthetic systems. Here, the authors report a...

nature.com
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I’m thrilled to share that our latest work, led by PhD scholar @_Das_Priyanka, is published in @embojournal! Using a bacterial mutant library screen, we identified that bacterial-induced ROS extends C. elegans lifespan by disrupting its iron homeostasis. embopress.org/doi/full/10.10…
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ShorterLab@ShorterLab8 Nov 2025
Phase separation to buffer growth-mediated dilution in synthetic circuits: Cell cell.com/cell/fulltext/S0092…
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Rachna Chaba@ChabaRachna5 Nov 2025
Excited to share Deeptodeep’s PhD work biorxiv.org/cgi/content/shor… Congrats on first & co-corr. authorship! We uncover redox switch as a novel mode of activation of E. coli envelope protease DegP that enables it to integrate various stress cues @caughtnd_act @DBS_IISERM @IiserMohali
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